Full text data of ZBTB8OS
ZBTB8OS
(ARCH)
[Confidence: low (only semi-automatic identification from reviews)]
Protein archease (Protein ZBTB8OS; Zinc finger and BTB domain-containing opposite strand protein 8)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Protein archease (Protein ZBTB8OS; Zinc finger and BTB domain-containing opposite strand protein 8)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q8IWT0
ID ARCH_HUMAN Reviewed; 167 AA.
AC Q8IWT0; Q5TGK5; Q6PDA1; Q8IWS9; Q8NEV6; Q8NEV7;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAY-2007, sequence version 2.
DT 22-JAN-2014, entry version 81.
DE RecName: Full=Protein archease;
DE AltName: Full=Protein ZBTB8OS;
DE AltName: Full=Zinc finger and BTB domain-containing opposite strand protein 8;
GN Name=ZBTB8OS; Synonyms=ARCH;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
RA Alliel P.M., Goudou D., Bitoun M., Langlois C., Rieger F., Seddiqi N.,
RA Perin J.P.;
RT "Structure, expression and sequence comparison of human and murine
RT archease.";
RL Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A.,
RA Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K.,
RA Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D.,
RA Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G.,
RA Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M.,
RA Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J.,
RA Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M.,
RA Loveland J., Lovell J., Lush M.J., Lyne R., Martin S.,
RA Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S.,
RA Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C.,
RA Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z.,
RA Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E.,
RA Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A.,
RA Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R.,
RA Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V.,
RA Beck S., Rogers J., Bentley D.R.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION.
RX PubMed=15162483; DOI=10.1002/prot.20141;
RA Canaves J.M.;
RT "Predicted role for the archease protein family based on structural
RT and sequence analysis of TM1083 and MTH1598, two proteins structurally
RT characterized through structural genomics efforts.";
RL Proteins 56:19-27(2004).
RN [5]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, MASS SPECTROMETRY, AND
RP CLEAVAGE OF INITIATOR METHIONINE.
RX PubMed=19413330; DOI=10.1021/ac9004309;
RA Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,
RA Mohammed S.;
RT "Lys-N and trypsin cover complementary parts of the phosphoproteome in
RT a refined SCX-based approach.";
RL Anal. Chem. 81:4493-4501(2009).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8IWT0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8IWT0-2; Sequence=VSP_024926;
CC -!- SIMILARITY: Belongs to the archease family.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM34477.1; Type=Erroneous initiation;
CC Sequence=AAN75223.1; Type=Erroneous initiation;
CC Sequence=AAN75224.1; Type=Erroneous initiation;
CC Sequence=CAI20020.1; Type=Erroneous initiation;
CC Sequence=CAI20021.1; Type=Erroneous initiation;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AY099493; AAM34477.1; ALT_INIT; mRNA.
DR EMBL; AY099494; AAM34478.1; -; mRNA.
DR EMBL; AY151084; AAN75223.1; ALT_INIT; mRNA.
DR EMBL; AY151085; AAN75224.1; ALT_INIT; mRNA.
DR EMBL; AL033529; CAI20020.1; ALT_INIT; Genomic_DNA.
DR EMBL; AC114489; CAI20020.1; JOINED; Genomic_DNA.
DR EMBL; AL033529; CAI20021.1; ALT_INIT; Genomic_DNA.
DR EMBL; AC114489; CAI20021.1; JOINED; Genomic_DNA.
DR EMBL; BC058843; AAH58843.1; -; mRNA.
DR RefSeq; NP_848642.1; NM_178547.2.
DR UniGene; Hs.655921; -.
DR ProteinModelPortal; Q8IWT0; -.
DR SMR; Q8IWT0; 29-157.
DR IntAct; Q8IWT0; 3.
DR STRING; 9606.ENSP00000417677; -.
DR PhosphoSite; Q8IWT0; -.
DR DMDM; 146286037; -.
DR PaxDb; Q8IWT0; -.
DR PRIDE; Q8IWT0; -.
DR DNASU; 339487; -.
DR Ensembl; ENST00000373501; ENSP00000362600; ENSG00000176261.
DR GeneID; 339487; -.
DR KEGG; hsa:339487; -.
DR CTD; 339487; -.
DR GeneCards; GC01M033065; -.
DR H-InvDB; HIX0028669; -.
DR HGNC; HGNC:24094; ZBTB8OS.
DR HPA; HPA044835; -.
DR HPA; HPA045317; -.
DR HPA; HPA046315; -.
DR HPA; HPA046331; -.
DR neXtProt; NX_Q8IWT0; -.
DR PharmGKB; PA142670540; -.
DR eggNOG; COG1371; -.
DR HOVERGEN; HBG104905; -.
DR InParanoid; Q8IWT0; -.
DR GenomeRNAi; 339487; -.
DR NextBio; 97428; -.
DR PRO; PR:Q8IWT0; -.
DR ArrayExpress; Q8IWT0; -.
DR Bgee; Q8IWT0; -.
DR CleanEx; HS_ZBTB8OS; -.
DR Genevestigator; Q8IWT0; -.
DR Gene3D; 3.55.10.10; -; 1.
DR InterPro; IPR002804; Archease.
DR InterPro; IPR023572; Archease_dom.
DR PANTHER; PTHR12682; PTHR12682; 1.
DR Pfam; PF01951; Archease; 1.
DR ProDom; PD012969; PD012969; 1.
DR SUPFAM; SSF69819; SSF69819; 1.
PE 1: Evidence at protein level;
KW Acetylation; Alternative splicing; Complete proteome;
KW Reference proteome.
FT INIT_MET 1 1 Removed.
FT CHAIN 2 167 Protein archease.
FT /FTId=PRO_0000285950.
FT MOD_RES 2 2 N-acetylalanine.
FT VAR_SEQ 110 167 EVKVLSIDQRNFKLRSIGWGEEFSLSKHPQGTEVKAITYSA
FT MQVYNEENPEVFVIIDI -> VGRRIFIVQAPSGNRSQSNN
FT IFSNAGL (in isoform 2).
FT /FTId=VSP_024926.
FT CONFLICT 51 51 E -> V (in Ref. 1; AAM34478).
FT CONFLICT 76 76 V -> A (in Ref. 1; AAM34478).
FT CONFLICT 93 93 L -> S (in Ref. 1; AAM34478).
FT CONFLICT 119 119 R -> G (in Ref. 1; AAM34478).
FT CONFLICT 137 137 H -> R (in Ref. 1; AAM34478).
SQ SEQUENCE 167 AA; 19491 MW; 26EC7F03CA7B42F1 CRC64;
MAQEEEDVRD YNLTEEQKAI KAKYPPVNRK YEYLDHTADV QLHAWGDTLE EAFEQCAMAM
FGYMTDTGTV EPLQTVEVET QGDDLQSLLF HFLDEWLYKF SADEFFIPRE VKVLSIDQRN
FKLRSIGWGE EFSLSKHPQG TEVKAITYSA MQVYNEENPE VFVIIDI
//
ID ARCH_HUMAN Reviewed; 167 AA.
AC Q8IWT0; Q5TGK5; Q6PDA1; Q8IWS9; Q8NEV6; Q8NEV7;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAY-2007, sequence version 2.
DT 22-JAN-2014, entry version 81.
DE RecName: Full=Protein archease;
DE AltName: Full=Protein ZBTB8OS;
DE AltName: Full=Zinc finger and BTB domain-containing opposite strand protein 8;
GN Name=ZBTB8OS; Synonyms=ARCH;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
RA Alliel P.M., Goudou D., Bitoun M., Langlois C., Rieger F., Seddiqi N.,
RA Perin J.P.;
RT "Structure, expression and sequence comparison of human and murine
RT archease.";
RL Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A.,
RA Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K.,
RA Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D.,
RA Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G.,
RA Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M.,
RA Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J.,
RA Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M.,
RA Loveland J., Lovell J., Lush M.J., Lyne R., Martin S.,
RA Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S.,
RA Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C.,
RA Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z.,
RA Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E.,
RA Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A.,
RA Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R.,
RA Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V.,
RA Beck S., Rogers J., Bentley D.R.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION.
RX PubMed=15162483; DOI=10.1002/prot.20141;
RA Canaves J.M.;
RT "Predicted role for the archease protein family based on structural
RT and sequence analysis of TM1083 and MTH1598, two proteins structurally
RT characterized through structural genomics efforts.";
RL Proteins 56:19-27(2004).
RN [5]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, MASS SPECTROMETRY, AND
RP CLEAVAGE OF INITIATOR METHIONINE.
RX PubMed=19413330; DOI=10.1021/ac9004309;
RA Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,
RA Mohammed S.;
RT "Lys-N and trypsin cover complementary parts of the phosphoproteome in
RT a refined SCX-based approach.";
RL Anal. Chem. 81:4493-4501(2009).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8IWT0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8IWT0-2; Sequence=VSP_024926;
CC -!- SIMILARITY: Belongs to the archease family.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM34477.1; Type=Erroneous initiation;
CC Sequence=AAN75223.1; Type=Erroneous initiation;
CC Sequence=AAN75224.1; Type=Erroneous initiation;
CC Sequence=CAI20020.1; Type=Erroneous initiation;
CC Sequence=CAI20021.1; Type=Erroneous initiation;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AY099493; AAM34477.1; ALT_INIT; mRNA.
DR EMBL; AY099494; AAM34478.1; -; mRNA.
DR EMBL; AY151084; AAN75223.1; ALT_INIT; mRNA.
DR EMBL; AY151085; AAN75224.1; ALT_INIT; mRNA.
DR EMBL; AL033529; CAI20020.1; ALT_INIT; Genomic_DNA.
DR EMBL; AC114489; CAI20020.1; JOINED; Genomic_DNA.
DR EMBL; AL033529; CAI20021.1; ALT_INIT; Genomic_DNA.
DR EMBL; AC114489; CAI20021.1; JOINED; Genomic_DNA.
DR EMBL; BC058843; AAH58843.1; -; mRNA.
DR RefSeq; NP_848642.1; NM_178547.2.
DR UniGene; Hs.655921; -.
DR ProteinModelPortal; Q8IWT0; -.
DR SMR; Q8IWT0; 29-157.
DR IntAct; Q8IWT0; 3.
DR STRING; 9606.ENSP00000417677; -.
DR PhosphoSite; Q8IWT0; -.
DR DMDM; 146286037; -.
DR PaxDb; Q8IWT0; -.
DR PRIDE; Q8IWT0; -.
DR DNASU; 339487; -.
DR Ensembl; ENST00000373501; ENSP00000362600; ENSG00000176261.
DR GeneID; 339487; -.
DR KEGG; hsa:339487; -.
DR CTD; 339487; -.
DR GeneCards; GC01M033065; -.
DR H-InvDB; HIX0028669; -.
DR HGNC; HGNC:24094; ZBTB8OS.
DR HPA; HPA044835; -.
DR HPA; HPA045317; -.
DR HPA; HPA046315; -.
DR HPA; HPA046331; -.
DR neXtProt; NX_Q8IWT0; -.
DR PharmGKB; PA142670540; -.
DR eggNOG; COG1371; -.
DR HOVERGEN; HBG104905; -.
DR InParanoid; Q8IWT0; -.
DR GenomeRNAi; 339487; -.
DR NextBio; 97428; -.
DR PRO; PR:Q8IWT0; -.
DR ArrayExpress; Q8IWT0; -.
DR Bgee; Q8IWT0; -.
DR CleanEx; HS_ZBTB8OS; -.
DR Genevestigator; Q8IWT0; -.
DR Gene3D; 3.55.10.10; -; 1.
DR InterPro; IPR002804; Archease.
DR InterPro; IPR023572; Archease_dom.
DR PANTHER; PTHR12682; PTHR12682; 1.
DR Pfam; PF01951; Archease; 1.
DR ProDom; PD012969; PD012969; 1.
DR SUPFAM; SSF69819; SSF69819; 1.
PE 1: Evidence at protein level;
KW Acetylation; Alternative splicing; Complete proteome;
KW Reference proteome.
FT INIT_MET 1 1 Removed.
FT CHAIN 2 167 Protein archease.
FT /FTId=PRO_0000285950.
FT MOD_RES 2 2 N-acetylalanine.
FT VAR_SEQ 110 167 EVKVLSIDQRNFKLRSIGWGEEFSLSKHPQGTEVKAITYSA
FT MQVYNEENPEVFVIIDI -> VGRRIFIVQAPSGNRSQSNN
FT IFSNAGL (in isoform 2).
FT /FTId=VSP_024926.
FT CONFLICT 51 51 E -> V (in Ref. 1; AAM34478).
FT CONFLICT 76 76 V -> A (in Ref. 1; AAM34478).
FT CONFLICT 93 93 L -> S (in Ref. 1; AAM34478).
FT CONFLICT 119 119 R -> G (in Ref. 1; AAM34478).
FT CONFLICT 137 137 H -> R (in Ref. 1; AAM34478).
SQ SEQUENCE 167 AA; 19491 MW; 26EC7F03CA7B42F1 CRC64;
MAQEEEDVRD YNLTEEQKAI KAKYPPVNRK YEYLDHTADV QLHAWGDTLE EAFEQCAMAM
FGYMTDTGTV EPLQTVEVET QGDDLQSLLF HFLDEWLYKF SADEFFIPRE VKVLSIDQRN
FKLRSIGWGE EFSLSKHPQG TEVKAITYSA MQVYNEENPE VFVIIDI
//