Full text data of ACTR10
ACTR10
(ACTR11, ARP11)
[Confidence: low (only semi-automatic identification from reviews)]
Actin-related protein 10 (Actin-related protein 11; hARP11)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Actin-related protein 10 (Actin-related protein 11; hARP11)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q9NZ32
ID ARP10_HUMAN Reviewed; 417 AA.
AC Q9NZ32; Q9H9Y5; Q9NWY2;
DT 27-JAN-2003, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-OCT-2000, sequence version 1.
DT 22-JAN-2014, entry version 99.
DE RecName: Full=Actin-related protein 10;
DE AltName: Full=Actin-related protein 11;
DE Short=hARP11;
GN Name=ACTR10; Synonyms=ACTR11, ARP11;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Hypothalamus;
RX PubMed=10931946; DOI=10.1073/pnas.160270997;
RA Hu R.-M., Han Z.-G., Song H.-D., Peng Y.-D., Huang Q.-H., Ren S.-X.,
RA Gu Y.-J., Huang C.-H., Li Y.-B., Jiang C.-L., Fu G., Zhang Q.-H.,
RA Gu B.-W., Dai M., Mao Y.-F., Gao G.-F., Rong R., Ye M., Zhou J.,
RA Xu S.-H., Gu J., Shi J.-X., Jin W.-R., Zhang C.-K., Wu T.-M.,
RA Huang G.-Y., Chen Z., Chen M.-D., Chen J.-L.;
RT "Gene expression profiling in the human hypothalamus-pituitary-adrenal
RT axis and full-length cDNA cloning.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton (By similarity).
CC -!- SIMILARITY: Belongs to the actin family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AF220190; AAF67655.1; -; mRNA.
DR EMBL; AK000544; BAA91243.1; -; mRNA.
DR EMBL; AK022534; BAB14083.1; -; mRNA.
DR EMBL; BC011997; AAH11997.1; -; mRNA.
DR RefSeq; NP_060947.1; NM_018477.2.
DR UniGene; Hs.509451; -.
DR ProteinModelPortal; Q9NZ32; -.
DR SMR; Q9NZ32; 14-382.
DR IntAct; Q9NZ32; 6.
DR STRING; 9606.ENSP00000254286; -.
DR PhosphoSite; Q9NZ32; -.
DR DMDM; 27923739; -.
DR PaxDb; Q9NZ32; -.
DR PRIDE; Q9NZ32; -.
DR DNASU; 55860; -.
DR Ensembl; ENST00000254286; ENSP00000254286; ENSG00000131966.
DR GeneID; 55860; -.
DR KEGG; hsa:55860; -.
DR UCSC; uc001xdf.3; human.
DR CTD; 55860; -.
DR GeneCards; GC14P058666; -.
DR HGNC; HGNC:17372; ACTR10.
DR neXtProt; NX_Q9NZ32; -.
DR PharmGKB; PA134899463; -.
DR eggNOG; COG5277; -.
DR HOGENOM; HOG000034069; -.
DR HOVERGEN; HBG050578; -.
DR InParanoid; Q9NZ32; -.
DR KO; K16576; -.
DR OMA; KPIKVVQ; -.
DR SignaLink; Q9NZ32; -.
DR GenomeRNAi; 55860; -.
DR NextBio; 61151; -.
DR PRO; PR:Q9NZ32; -.
DR ArrayExpress; Q9NZ32; -.
DR Bgee; Q9NZ32; -.
DR CleanEx; HS_ACTR10; -.
DR Genevestigator; Q9NZ32; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005869; C:dynactin complex; IEA:Ensembl.
DR GO; GO:0007018; P:microtubule-based movement; IEA:Ensembl.
DR InterPro; IPR004000; Actin-related.
DR InterPro; IPR027127; Arp10.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR PANTHER; PTHR11937:SF14; PTHR11937:SF14; 1.
DR Pfam; PF00022; Actin; 1.
DR SMART; SM00268; ACTIN; 1.
PE 1: Evidence at protein level;
KW Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1 417 Actin-related protein 10.
FT /FTId=PRO_0000089131.
FT CONFLICT 53 53 R -> K (in Ref. 2; BAA91243).
FT CONFLICT 93 93 E -> K (in Ref. 2; BAA91243).
FT CONFLICT 219 219 D -> G (in Ref. 2; BAB14083).
SQ SEQUENCE 417 AA; 46307 MW; DF351A7B299DB7C1 CRC64;
MPLYEGLGSG GEKTAVVIDL GEAFTKCGFA GETGPRCIIP SVIKRAGMPK PVRVVQYNIN
TEELYSYLKE FIHILYFRHL LVNPRDRRVV IIESVLCPSH FRETLTRVLF KYFEVPSVLL
APSHLMALLT LGINSAMVLD CGYRESLVLP IYEGIPVLNC WGALPLGGKA LHKELETQLL
EQCTVDTSVA KEQSLPSVMG SVPEGVLEDI KARTCFVSDL KRGLKIQAAK FNIDGNNERP
SPPPNVDYPL DGEKILHILG SIRDSVVEIL FEQDNEEQSV ATLILDSLIQ CPIDTRKQLA
ENLVVIGGTS MLPGFLHRLL AEIRYLVEKP KYKKALGTKT FRIHTPPAKA NCVAWLGGAI
FGALQDILGS RSVSKEYYNQ TGRIPDWCSL NNPPLEMMFD VGKTQPPLMK RAFSTEK
//
ID ARP10_HUMAN Reviewed; 417 AA.
AC Q9NZ32; Q9H9Y5; Q9NWY2;
DT 27-JAN-2003, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-OCT-2000, sequence version 1.
DT 22-JAN-2014, entry version 99.
DE RecName: Full=Actin-related protein 10;
DE AltName: Full=Actin-related protein 11;
DE Short=hARP11;
GN Name=ACTR10; Synonyms=ACTR11, ARP11;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Hypothalamus;
RX PubMed=10931946; DOI=10.1073/pnas.160270997;
RA Hu R.-M., Han Z.-G., Song H.-D., Peng Y.-D., Huang Q.-H., Ren S.-X.,
RA Gu Y.-J., Huang C.-H., Li Y.-B., Jiang C.-L., Fu G., Zhang Q.-H.,
RA Gu B.-W., Dai M., Mao Y.-F., Gao G.-F., Rong R., Ye M., Zhou J.,
RA Xu S.-H., Gu J., Shi J.-X., Jin W.-R., Zhang C.-K., Wu T.-M.,
RA Huang G.-Y., Chen Z., Chen M.-D., Chen J.-L.;
RT "Gene expression profiling in the human hypothalamus-pituitary-adrenal
RT axis and full-length cDNA cloning.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton (By similarity).
CC -!- SIMILARITY: Belongs to the actin family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AF220190; AAF67655.1; -; mRNA.
DR EMBL; AK000544; BAA91243.1; -; mRNA.
DR EMBL; AK022534; BAB14083.1; -; mRNA.
DR EMBL; BC011997; AAH11997.1; -; mRNA.
DR RefSeq; NP_060947.1; NM_018477.2.
DR UniGene; Hs.509451; -.
DR ProteinModelPortal; Q9NZ32; -.
DR SMR; Q9NZ32; 14-382.
DR IntAct; Q9NZ32; 6.
DR STRING; 9606.ENSP00000254286; -.
DR PhosphoSite; Q9NZ32; -.
DR DMDM; 27923739; -.
DR PaxDb; Q9NZ32; -.
DR PRIDE; Q9NZ32; -.
DR DNASU; 55860; -.
DR Ensembl; ENST00000254286; ENSP00000254286; ENSG00000131966.
DR GeneID; 55860; -.
DR KEGG; hsa:55860; -.
DR UCSC; uc001xdf.3; human.
DR CTD; 55860; -.
DR GeneCards; GC14P058666; -.
DR HGNC; HGNC:17372; ACTR10.
DR neXtProt; NX_Q9NZ32; -.
DR PharmGKB; PA134899463; -.
DR eggNOG; COG5277; -.
DR HOGENOM; HOG000034069; -.
DR HOVERGEN; HBG050578; -.
DR InParanoid; Q9NZ32; -.
DR KO; K16576; -.
DR OMA; KPIKVVQ; -.
DR SignaLink; Q9NZ32; -.
DR GenomeRNAi; 55860; -.
DR NextBio; 61151; -.
DR PRO; PR:Q9NZ32; -.
DR ArrayExpress; Q9NZ32; -.
DR Bgee; Q9NZ32; -.
DR CleanEx; HS_ACTR10; -.
DR Genevestigator; Q9NZ32; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005869; C:dynactin complex; IEA:Ensembl.
DR GO; GO:0007018; P:microtubule-based movement; IEA:Ensembl.
DR InterPro; IPR004000; Actin-related.
DR InterPro; IPR027127; Arp10.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR PANTHER; PTHR11937:SF14; PTHR11937:SF14; 1.
DR Pfam; PF00022; Actin; 1.
DR SMART; SM00268; ACTIN; 1.
PE 1: Evidence at protein level;
KW Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1 417 Actin-related protein 10.
FT /FTId=PRO_0000089131.
FT CONFLICT 53 53 R -> K (in Ref. 2; BAA91243).
FT CONFLICT 93 93 E -> K (in Ref. 2; BAA91243).
FT CONFLICT 219 219 D -> G (in Ref. 2; BAB14083).
SQ SEQUENCE 417 AA; 46307 MW; DF351A7B299DB7C1 CRC64;
MPLYEGLGSG GEKTAVVIDL GEAFTKCGFA GETGPRCIIP SVIKRAGMPK PVRVVQYNIN
TEELYSYLKE FIHILYFRHL LVNPRDRRVV IIESVLCPSH FRETLTRVLF KYFEVPSVLL
APSHLMALLT LGINSAMVLD CGYRESLVLP IYEGIPVLNC WGALPLGGKA LHKELETQLL
EQCTVDTSVA KEQSLPSVMG SVPEGVLEDI KARTCFVSDL KRGLKIQAAK FNIDGNNERP
SPPPNVDYPL DGEKILHILG SIRDSVVEIL FEQDNEEQSV ATLILDSLIQ CPIDTRKQLA
ENLVVIGGTS MLPGFLHRLL AEIRYLVEKP KYKKALGTKT FRIHTPPAKA NCVAWLGGAI
FGALQDILGS RSVSKEYYNQ TGRIPDWCSL NNPPLEMMFD VGKTQPPLMK RAFSTEK
//