Full text data of TPM1
TPM1
[Confidence: high (present in two of the MS resources)]
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
B7Z596
ID B7Z596_HUMAN Unreviewed; 275 AA.
AC B7Z596;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
read moreDT 22-JAN-2014, entry version 29.
DE SubName: Full=Tropomyosin alpha-1 chain;
DE SubName: Full=cDNA FLJ55130, highly similar to Rattus norvegicus tropomyosin 1, alpha (Tpm1), transcript variant 8, mRNA;
GN Name=TPM1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16572171; DOI=10.1038/nature04601;
RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA Nusbaum C.;
RT "Analysis of the DNA sequence and duplication history of human
RT chromosome 15.";
RL Nature 440:671-675(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT "NEDO human cDNA sequencing project focused on splicing variants.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
CC -!- SIMILARITY: Belongs to the tropomyosin family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AC079328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK298625; BAH12832.1; -; mRNA.
DR RefSeq; XP_005254703.1; XM_005254646.1.
DR UniGene; Hs.133892; -.
DR UniGene; Hs.602995; -.
DR ProteinModelPortal; B7Z596; -.
DR SMR; B7Z596; 7-226.
DR PRIDE; B7Z596; -.
DR Ensembl; ENST00000560959; ENSP00000453724; ENSG00000140416.
DR GeneID; 7168; -.
DR UCSC; uc010uif.2; human.
DR HGNC; HGNC:12010; TPM1.
DR HOVERGEN; HBG107404; -.
DR ChiTaRS; TPM1; human.
DR NextBio; 35479675; -.
DR ArrayExpress; B7Z596; -.
DR GO; GO:0015629; C:actin cytoskeleton; IDA:HPA.
DR GO; GO:0005737; C:cytoplasm; IDA:HPA.
DR InterPro; IPR000533; Tropomyosin.
DR Pfam; PF00261; Tropomyosin; 1.
DR PRINTS; PR00194; TROPOMYOSIN.
DR PROSITE; PS00326; TROPOMYOSIN; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Complete proteome; Reference proteome.
SQ SEQUENCE 275 AA; 31753 MW; 449EE4040F0D2CC7 CRC64;
MAGSSSLEAV RRKIRSLQEQ ADAAEERAGT LQRELDHERK LRETAEADVA SLNRRIQLVE
EELDRAQERL ATALQKLEEA EKAADESERG MKVIESRAQK DEEKMEIQEI QLKEAKHIAE
DADRKYEEVA RKLVIIESDL ERAEERAELS EGQVRQLEEQ LRIMDQTLKA LMAAEDKYSQ
KEDRYEEEIK VLSDKLKEAE TRAEFAERSV TKLEKSIDDL EGKILSSVFS LILMVEYQPG
KTIFQFKGIH IDTLLCTCTF FLCVLWGFSL WLLNS
//
ID B7Z596_HUMAN Unreviewed; 275 AA.
AC B7Z596;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
read moreDT 22-JAN-2014, entry version 29.
DE SubName: Full=Tropomyosin alpha-1 chain;
DE SubName: Full=cDNA FLJ55130, highly similar to Rattus norvegicus tropomyosin 1, alpha (Tpm1), transcript variant 8, mRNA;
GN Name=TPM1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16572171; DOI=10.1038/nature04601;
RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA Nusbaum C.;
RT "Analysis of the DNA sequence and duplication history of human
RT chromosome 15.";
RL Nature 440:671-675(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT "NEDO human cDNA sequencing project focused on splicing variants.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
CC -!- SIMILARITY: Belongs to the tropomyosin family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AC079328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK298625; BAH12832.1; -; mRNA.
DR RefSeq; XP_005254703.1; XM_005254646.1.
DR UniGene; Hs.133892; -.
DR UniGene; Hs.602995; -.
DR ProteinModelPortal; B7Z596; -.
DR SMR; B7Z596; 7-226.
DR PRIDE; B7Z596; -.
DR Ensembl; ENST00000560959; ENSP00000453724; ENSG00000140416.
DR GeneID; 7168; -.
DR UCSC; uc010uif.2; human.
DR HGNC; HGNC:12010; TPM1.
DR HOVERGEN; HBG107404; -.
DR ChiTaRS; TPM1; human.
DR NextBio; 35479675; -.
DR ArrayExpress; B7Z596; -.
DR GO; GO:0015629; C:actin cytoskeleton; IDA:HPA.
DR GO; GO:0005737; C:cytoplasm; IDA:HPA.
DR InterPro; IPR000533; Tropomyosin.
DR Pfam; PF00261; Tropomyosin; 1.
DR PRINTS; PR00194; TROPOMYOSIN.
DR PROSITE; PS00326; TROPOMYOSIN; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Complete proteome; Reference proteome.
SQ SEQUENCE 275 AA; 31753 MW; 449EE4040F0D2CC7 CRC64;
MAGSSSLEAV RRKIRSLQEQ ADAAEERAGT LQRELDHERK LRETAEADVA SLNRRIQLVE
EELDRAQERL ATALQKLEEA EKAADESERG MKVIESRAQK DEEKMEIQEI QLKEAKHIAE
DADRKYEEVA RKLVIIESDL ERAEERAELS EGQVRQLEEQ LRIMDQTLKA LMAAEDKYSQ
KEDRYEEEIK VLSDKLKEAE TRAEFAERSV TKLEKSIDDL EGKILSSVFS LILMVEYQPG
KTIFQFKGIH IDTLLCTCTF FLCVLWGFSL WLLNS
//