Full text data of C6orf211
C6orf211
[Confidence: low (only semi-automatic identification from reviews)]
UPF0364 protein C6orf211
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UPF0364 protein C6orf211
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q9H993
ID CF211_HUMAN Reviewed; 441 AA.
AC Q9H993; Q96FC6; Q9UFY5;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAR-2001, sequence version 1.
DT 22-JAN-2014, entry version 85.
DE RecName: Full=UPF0364 protein C6orf211;
GN Name=C6orf211;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Teratocarcinoma;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=14574404; DOI=10.1038/nature02055;
RA Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
RA Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
RA Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
RA Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
RA Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
RA Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
RA Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
RA Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
RA Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
RA Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
RA Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
RA Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
RA Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
RA Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
RA Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
RA Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
RA Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
RA McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
RA Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
RA Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
RA Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
RA Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
RA Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
RA Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
RA Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
RA Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
RA Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
RA Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
RT "The DNA sequence and analysis of human chromosome 6.";
RL Nature 425:805-811(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT ARG-77.
RC TISSUE=Lymph;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-238.
RC TISSUE=Fetal kidney;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,
RA Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,
RA Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [5]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, MASS SPECTROMETRY, AND
RP CLEAVAGE OF INITIATOR METHIONINE.
RX PubMed=19413330; DOI=10.1021/ac9004309;
RA Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,
RA Mohammed S.;
RT "Lys-N and trypsin cover complementary parts of the phosphoproteome in
RT a refined SCX-based approach.";
RL Anal. Chem. 81:4493-4501(2009).
RN [6]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-40, AND MASS SPECTROMETRY.
RX PubMed=19608861; DOI=10.1126/science.1175371;
RA Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M.,
RA Walther T.C., Olsen J.V., Mann M.;
RT "Lysine acetylation targets protein complexes and co-regulates major
RT cellular functions.";
RL Science 325:834-840(2009).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [8]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, AND MASS SPECTROMETRY.
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E.,
RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K.,
RA Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-
RT terminal acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- INTERACTION:
CC O00422:SAP18; NbExp=1; IntAct=EBI-1046033, EBI-1044156;
CC -!- SIMILARITY: Belongs to the UPF0364 family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AK022972; BAB14339.1; -; mRNA.
DR EMBL; AL590543; CAI10942.1; -; Genomic_DNA.
DR EMBL; BC011348; AAH11348.1; -; mRNA.
DR EMBL; AL110241; CAB53692.2; -; mRNA.
DR PIR; T14772; T14772.
DR RefSeq; NP_001273491.1; NM_001286562.1.
DR RefSeq; NP_078849.1; NM_024573.2.
DR UniGene; Hs.15929; -.
DR ProteinModelPortal; Q9H993; -.
DR SMR; Q9H993; 4-434.
DR IntAct; Q9H993; 1.
DR STRING; 9606.ENSP00000356263; -.
DR PhosphoSite; Q9H993; -.
DR DMDM; 74752737; -.
DR PaxDb; Q9H993; -.
DR PeptideAtlas; Q9H993; -.
DR PRIDE; Q9H993; -.
DR DNASU; 79624; -.
DR Ensembl; ENST00000367294; ENSP00000356263; ENSG00000146476.
DR GeneID; 79624; -.
DR KEGG; hsa:79624; -.
DR UCSC; uc003qok.1; human.
DR CTD; 79624; -.
DR GeneCards; GC06P151773; -.
DR H-InvDB; HIX0006300; -.
DR HGNC; HGNC:17872; C6orf211.
DR HPA; HPA003004; -.
DR HPA; HPA005819; -.
DR neXtProt; NX_Q9H993; -.
DR PharmGKB; PA134870747; -.
DR eggNOG; NOG84915; -.
DR HOGENOM; HOG000172710; -.
DR HOVERGEN; HBG054833; -.
DR InParanoid; Q9H993; -.
DR OMA; QGKDFMN; -.
DR OrthoDB; EOG7XSTDB; -.
DR PhylomeDB; Q9H993; -.
DR GenomeRNAi; 79624; -.
DR NextBio; 68701; -.
DR ArrayExpress; Q9H993; -.
DR Bgee; Q9H993; -.
DR CleanEx; HS_C6orf211; -.
DR Genevestigator; Q9H993; -.
DR InterPro; IPR002791; DUF89.
DR Pfam; PF01937; DUF89; 1.
DR SUPFAM; SSF111321; SSF111321; 1.
PE 1: Evidence at protein level;
KW Acetylation; Complete proteome; Polymorphism; Reference proteome.
FT INIT_MET 1 1 Removed.
FT CHAIN 2 441 UPF0364 protein C6orf211.
FT /FTId=PRO_0000230795.
FT MOD_RES 2 2 N-acetylalanine.
FT MOD_RES 40 40 N6-acetyllysine.
FT VARIANT 73 73 K -> N (in dbSNP:rs35036943).
FT /FTId=VAR_053090.
FT VARIANT 77 77 P -> R (in dbSNP:rs17850732).
FT /FTId=VAR_025791.
FT VARIANT 150 150 G -> E (in dbSNP:rs35734927).
FT /FTId=VAR_053091.
FT VARIANT 154 154 S -> A (in dbSNP:rs34437617).
FT /FTId=VAR_053092.
FT VARIANT 161 161 H -> P (in dbSNP:rs36037706).
FT /FTId=VAR_053093.
FT VARIANT 264 264 I -> V (in dbSNP:rs35989216).
FT /FTId=VAR_053094.
FT VARIANT 317 317 A -> T (in dbSNP:rs35972078).
FT /FTId=VAR_053095.
FT CONFLICT 120 121 MY -> ID (in Ref. 3; AAH11348).
FT CONFLICT 148 148 F -> S (in Ref. 4; CAB53692).
FT CONFLICT 173 173 D -> Y (in Ref. 3; AAH11348).
FT CONFLICT 220 220 F -> Y (in Ref. 4; CAB53692).
SQ SEQUENCE 441 AA; 51172 MW; 3BE4D15528FDFC4E CRC64;
MAVVPASLSG QDVGSFAYLT IKDRIPQILT KVIDTLHRHK SEFFEKHGEE GVEAEKKAIS
LLSKLRNELQ TDKPFIPLVE KFVDTDIWNQ YLEYQQSLLN ESDGKSRWFY SPWLLVECYM
YRRIHEAIIQ SPPIDYFDVF KESKEQNFYG SQESIIALCT HLQQLIRTIE DLDENQLKDE
FFKLLQISLW GNKCDLSLSG GESSSQNTNV LNSLEDLKPF ILLNDMEHLW SLLSNCKKTR
EKASATRVYI VLDNSGFELV TDLILADFLL SSELATEVHF YGKTIPWFVS DTTIHDFNWL
IEQVKHSNHK WMSKCGADWE EYIKMGKWVY HNHIFWTLPH EYCAMPQVAP DLYAELQKAH
LILFKGDLNY RKLTGDRKWE FSVPFHQALN GFHPAPLCTI RTLKAEIQVG LQPGQGEQLL
ASEPSWWTTG KYGIFQYDGP L
//
ID CF211_HUMAN Reviewed; 441 AA.
AC Q9H993; Q96FC6; Q9UFY5;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAR-2001, sequence version 1.
DT 22-JAN-2014, entry version 85.
DE RecName: Full=UPF0364 protein C6orf211;
GN Name=C6orf211;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Teratocarcinoma;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=14574404; DOI=10.1038/nature02055;
RA Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
RA Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
RA Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
RA Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
RA Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
RA Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
RA Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
RA Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
RA Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
RA Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
RA Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
RA Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
RA Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
RA Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
RA Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
RA Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
RA Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
RA McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
RA Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
RA Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
RA Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
RA Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
RA Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
RA Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
RA Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
RA Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
RA Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
RA Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
RT "The DNA sequence and analysis of human chromosome 6.";
RL Nature 425:805-811(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT ARG-77.
RC TISSUE=Lymph;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-238.
RC TISSUE=Fetal kidney;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,
RA Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,
RA Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [5]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, MASS SPECTROMETRY, AND
RP CLEAVAGE OF INITIATOR METHIONINE.
RX PubMed=19413330; DOI=10.1021/ac9004309;
RA Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,
RA Mohammed S.;
RT "Lys-N and trypsin cover complementary parts of the phosphoproteome in
RT a refined SCX-based approach.";
RL Anal. Chem. 81:4493-4501(2009).
RN [6]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-40, AND MASS SPECTROMETRY.
RX PubMed=19608861; DOI=10.1126/science.1175371;
RA Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M.,
RA Walther T.C., Olsen J.V., Mann M.;
RT "Lysine acetylation targets protein complexes and co-regulates major
RT cellular functions.";
RL Science 325:834-840(2009).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [8]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, AND MASS SPECTROMETRY.
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E.,
RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K.,
RA Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-
RT terminal acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- INTERACTION:
CC O00422:SAP18; NbExp=1; IntAct=EBI-1046033, EBI-1044156;
CC -!- SIMILARITY: Belongs to the UPF0364 family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AK022972; BAB14339.1; -; mRNA.
DR EMBL; AL590543; CAI10942.1; -; Genomic_DNA.
DR EMBL; BC011348; AAH11348.1; -; mRNA.
DR EMBL; AL110241; CAB53692.2; -; mRNA.
DR PIR; T14772; T14772.
DR RefSeq; NP_001273491.1; NM_001286562.1.
DR RefSeq; NP_078849.1; NM_024573.2.
DR UniGene; Hs.15929; -.
DR ProteinModelPortal; Q9H993; -.
DR SMR; Q9H993; 4-434.
DR IntAct; Q9H993; 1.
DR STRING; 9606.ENSP00000356263; -.
DR PhosphoSite; Q9H993; -.
DR DMDM; 74752737; -.
DR PaxDb; Q9H993; -.
DR PeptideAtlas; Q9H993; -.
DR PRIDE; Q9H993; -.
DR DNASU; 79624; -.
DR Ensembl; ENST00000367294; ENSP00000356263; ENSG00000146476.
DR GeneID; 79624; -.
DR KEGG; hsa:79624; -.
DR UCSC; uc003qok.1; human.
DR CTD; 79624; -.
DR GeneCards; GC06P151773; -.
DR H-InvDB; HIX0006300; -.
DR HGNC; HGNC:17872; C6orf211.
DR HPA; HPA003004; -.
DR HPA; HPA005819; -.
DR neXtProt; NX_Q9H993; -.
DR PharmGKB; PA134870747; -.
DR eggNOG; NOG84915; -.
DR HOGENOM; HOG000172710; -.
DR HOVERGEN; HBG054833; -.
DR InParanoid; Q9H993; -.
DR OMA; QGKDFMN; -.
DR OrthoDB; EOG7XSTDB; -.
DR PhylomeDB; Q9H993; -.
DR GenomeRNAi; 79624; -.
DR NextBio; 68701; -.
DR ArrayExpress; Q9H993; -.
DR Bgee; Q9H993; -.
DR CleanEx; HS_C6orf211; -.
DR Genevestigator; Q9H993; -.
DR InterPro; IPR002791; DUF89.
DR Pfam; PF01937; DUF89; 1.
DR SUPFAM; SSF111321; SSF111321; 1.
PE 1: Evidence at protein level;
KW Acetylation; Complete proteome; Polymorphism; Reference proteome.
FT INIT_MET 1 1 Removed.
FT CHAIN 2 441 UPF0364 protein C6orf211.
FT /FTId=PRO_0000230795.
FT MOD_RES 2 2 N-acetylalanine.
FT MOD_RES 40 40 N6-acetyllysine.
FT VARIANT 73 73 K -> N (in dbSNP:rs35036943).
FT /FTId=VAR_053090.
FT VARIANT 77 77 P -> R (in dbSNP:rs17850732).
FT /FTId=VAR_025791.
FT VARIANT 150 150 G -> E (in dbSNP:rs35734927).
FT /FTId=VAR_053091.
FT VARIANT 154 154 S -> A (in dbSNP:rs34437617).
FT /FTId=VAR_053092.
FT VARIANT 161 161 H -> P (in dbSNP:rs36037706).
FT /FTId=VAR_053093.
FT VARIANT 264 264 I -> V (in dbSNP:rs35989216).
FT /FTId=VAR_053094.
FT VARIANT 317 317 A -> T (in dbSNP:rs35972078).
FT /FTId=VAR_053095.
FT CONFLICT 120 121 MY -> ID (in Ref. 3; AAH11348).
FT CONFLICT 148 148 F -> S (in Ref. 4; CAB53692).
FT CONFLICT 173 173 D -> Y (in Ref. 3; AAH11348).
FT CONFLICT 220 220 F -> Y (in Ref. 4; CAB53692).
SQ SEQUENCE 441 AA; 51172 MW; 3BE4D15528FDFC4E CRC64;
MAVVPASLSG QDVGSFAYLT IKDRIPQILT KVIDTLHRHK SEFFEKHGEE GVEAEKKAIS
LLSKLRNELQ TDKPFIPLVE KFVDTDIWNQ YLEYQQSLLN ESDGKSRWFY SPWLLVECYM
YRRIHEAIIQ SPPIDYFDVF KESKEQNFYG SQESIIALCT HLQQLIRTIE DLDENQLKDE
FFKLLQISLW GNKCDLSLSG GESSSQNTNV LNSLEDLKPF ILLNDMEHLW SLLSNCKKTR
EKASATRVYI VLDNSGFELV TDLILADFLL SSELATEVHF YGKTIPWFVS DTTIHDFNWL
IEQVKHSNHK WMSKCGADWE EYIKMGKWVY HNHIFWTLPH EYCAMPQVAP DLYAELQKAH
LILFKGDLNY RKLTGDRKWE FSVPFHQALN GFHPAPLCTI RTLKAEIQVG LQPGQGEQLL
ASEPSWWTTG KYGIFQYDGP L
//