Full text data of C9orf64
C9orf64
[Confidence: low (only semi-automatic identification from reviews)]
UPF0553 protein C9orf64
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UPF0553 protein C9orf64
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q5T6V5
ID CI064_HUMAN Reviewed; 341 AA.
AC Q5T6V5; B2RPI6; Q8N2B1; Q9BT18;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
read moreDT 21-DEC-2004, sequence version 1.
DT 22-JAN-2014, entry version 76.
DE RecName: Full=UPF0553 protein C9orf64;
GN Name=C9orf64;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164053; DOI=10.1038/nature02465;
RA Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E.,
RA Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C.,
RA Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S.,
RA Babbage A.K., Babbage S., Bagguley C.L., Bailey J., Banerjee R.,
RA Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P.,
RA Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W.,
RA Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G.,
RA Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M.,
RA Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W.,
RA Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A.,
RA Frankland J.A., French L., Fricker D.G., Garner P., Garnett J.,
RA Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA Kimberley A.M., King A., Knights A., Laird G.K., Langford C.,
RA Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M.,
RA Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S.,
RA McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J.,
RA Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R.,
RA Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M.,
RA Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M.,
RA Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A.,
RA Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P.,
RA Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W.,
RA Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M.,
RA Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S.,
RA Rogers J., Dunham I.;
RT "DNA sequence and analysis of human chromosome 9.";
RL Nature 429:369-374(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain, and Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP PROTEIN SEQUENCE OF 31-38; 136-148 AND 163-172, AND MASS SPECTROMETRY.
RC TISSUE=Osteosarcoma;
RA Bienvenut W.V., Glen H., Frame M.C.;
RL Submitted (MAR-2008) to UniProtKB.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 83-341.
RC TISSUE=Amygdala;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [7]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND MASS SPECTROMETRY.
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E.,
RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K.,
RA Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-
RT terminal acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- SIMILARITY: Belongs to the UPF0553 family.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC03538.1; Type=Erroneous initiation;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AL354733; CAI16017.1; -; Genomic_DNA.
DR EMBL; CH471089; EAW62673.1; -; Genomic_DNA.
DR EMBL; BC137461; AAI37462.1; -; mRNA.
DR EMBL; BC137462; AAI37463.1; -; mRNA.
DR EMBL; BC004407; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AK090882; BAC03538.1; ALT_INIT; mRNA.
DR RefSeq; NP_115683.3; NM_032307.3.
DR UniGene; Hs.208914; -.
DR ProteinModelPortal; Q5T6V5; -.
DR STRING; 9606.ENSP00000365522; -.
DR PhosphoSite; Q5T6V5; -.
DR DMDM; 73620030; -.
DR PaxDb; Q5T6V5; -.
DR PRIDE; Q5T6V5; -.
DR DNASU; 84267; -.
DR Ensembl; ENST00000376344; ENSP00000365522; ENSG00000165118.
DR GeneID; 84267; -.
DR KEGG; hsa:84267; -.
DR UCSC; uc004anb.3; human.
DR CTD; 84267; -.
DR GeneCards; GC09M086553; -.
DR HGNC; HGNC:28144; C9orf64.
DR MIM; 611342; gene.
DR neXtProt; NX_Q5T6V5; -.
DR PharmGKB; PA134865965; -.
DR eggNOG; NOG241762; -.
DR HOGENOM; HOG000010664; -.
DR HOVERGEN; HBG054936; -.
DR InParanoid; Q5T6V5; -.
DR OMA; FSFWSEL; -.
DR OrthoDB; EOG7CK379; -.
DR GeneWiki; C9orf64; -.
DR GenomeRNAi; 84267; -.
DR NextBio; 73816; -.
DR ArrayExpress; Q5T6V5; -.
DR Bgee; Q5T6V5; -.
DR CleanEx; HS_C9orf64; -.
DR Genevestigator; Q5T6V5; -.
DR InterPro; IPR019438; DUF2419.
DR PANTHER; PTHR21314; PTHR21314; 1.
DR Pfam; PF10343; DUF2419; 1.
PE 1: Evidence at protein level;
KW Acetylation; Complete proteome; Direct protein sequencing;
KW Reference proteome.
FT CHAIN 1 341 UPF0553 protein C9orf64.
FT /FTId=PRO_0000089700.
FT MOD_RES 1 1 N-acetylmethionine.
FT CONFLICT 324 324 H -> Y (in Ref. 5; BAC03538).
SQ SEQUENCE 341 AA; 39029 MW; 50AF5A7D7197D7B2 CRC64;
MDGLLNPRES SKFIAENSRD VFIDSGGVRR VAELLLAKAA GPELRVEGWK ALHELNPRAA
DEAAVNWVFV TDTLNFSFWS EQDEHKCVVR YRGKTYSGYW SLCAAVNRAL DEGIPITSAS
YYATVTLDQV RNILRSDTDV SMPLVEERHR ILNETGKILL EKFGGSFLNC VRESENSAQK
LMHLVVESFP SYRDVTLFEG KRVSFYKRAQ ILVADTWSVL EGKGDGCFKD ISSITMFADY
RLPQVLAHLG ALKYSDDLLK KLLKGEMLSY GDRQEVEIRG CSLWCVELIR DCLLELIEQK
GEKPNGEINS ILLDYYLWDY AHDHREDMKG IPFHRIRCIY Y
//
ID CI064_HUMAN Reviewed; 341 AA.
AC Q5T6V5; B2RPI6; Q8N2B1; Q9BT18;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
read moreDT 21-DEC-2004, sequence version 1.
DT 22-JAN-2014, entry version 76.
DE RecName: Full=UPF0553 protein C9orf64;
GN Name=C9orf64;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164053; DOI=10.1038/nature02465;
RA Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E.,
RA Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C.,
RA Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S.,
RA Babbage A.K., Babbage S., Bagguley C.L., Bailey J., Banerjee R.,
RA Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P.,
RA Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W.,
RA Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G.,
RA Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M.,
RA Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W.,
RA Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A.,
RA Frankland J.A., French L., Fricker D.G., Garner P., Garnett J.,
RA Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA Kimberley A.M., King A., Knights A., Laird G.K., Langford C.,
RA Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M.,
RA Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S.,
RA McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J.,
RA Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R.,
RA Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M.,
RA Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M.,
RA Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A.,
RA Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P.,
RA Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W.,
RA Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M.,
RA Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S.,
RA Rogers J., Dunham I.;
RT "DNA sequence and analysis of human chromosome 9.";
RL Nature 429:369-374(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain, and Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP PROTEIN SEQUENCE OF 31-38; 136-148 AND 163-172, AND MASS SPECTROMETRY.
RC TISSUE=Osteosarcoma;
RA Bienvenut W.V., Glen H., Frame M.C.;
RL Submitted (MAR-2008) to UniProtKB.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 83-341.
RC TISSUE=Amygdala;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [7]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND MASS SPECTROMETRY.
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E.,
RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K.,
RA Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-
RT terminal acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- SIMILARITY: Belongs to the UPF0553 family.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC03538.1; Type=Erroneous initiation;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AL354733; CAI16017.1; -; Genomic_DNA.
DR EMBL; CH471089; EAW62673.1; -; Genomic_DNA.
DR EMBL; BC137461; AAI37462.1; -; mRNA.
DR EMBL; BC137462; AAI37463.1; -; mRNA.
DR EMBL; BC004407; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AK090882; BAC03538.1; ALT_INIT; mRNA.
DR RefSeq; NP_115683.3; NM_032307.3.
DR UniGene; Hs.208914; -.
DR ProteinModelPortal; Q5T6V5; -.
DR STRING; 9606.ENSP00000365522; -.
DR PhosphoSite; Q5T6V5; -.
DR DMDM; 73620030; -.
DR PaxDb; Q5T6V5; -.
DR PRIDE; Q5T6V5; -.
DR DNASU; 84267; -.
DR Ensembl; ENST00000376344; ENSP00000365522; ENSG00000165118.
DR GeneID; 84267; -.
DR KEGG; hsa:84267; -.
DR UCSC; uc004anb.3; human.
DR CTD; 84267; -.
DR GeneCards; GC09M086553; -.
DR HGNC; HGNC:28144; C9orf64.
DR MIM; 611342; gene.
DR neXtProt; NX_Q5T6V5; -.
DR PharmGKB; PA134865965; -.
DR eggNOG; NOG241762; -.
DR HOGENOM; HOG000010664; -.
DR HOVERGEN; HBG054936; -.
DR InParanoid; Q5T6V5; -.
DR OMA; FSFWSEL; -.
DR OrthoDB; EOG7CK379; -.
DR GeneWiki; C9orf64; -.
DR GenomeRNAi; 84267; -.
DR NextBio; 73816; -.
DR ArrayExpress; Q5T6V5; -.
DR Bgee; Q5T6V5; -.
DR CleanEx; HS_C9orf64; -.
DR Genevestigator; Q5T6V5; -.
DR InterPro; IPR019438; DUF2419.
DR PANTHER; PTHR21314; PTHR21314; 1.
DR Pfam; PF10343; DUF2419; 1.
PE 1: Evidence at protein level;
KW Acetylation; Complete proteome; Direct protein sequencing;
KW Reference proteome.
FT CHAIN 1 341 UPF0553 protein C9orf64.
FT /FTId=PRO_0000089700.
FT MOD_RES 1 1 N-acetylmethionine.
FT CONFLICT 324 324 H -> Y (in Ref. 5; BAC03538).
SQ SEQUENCE 341 AA; 39029 MW; 50AF5A7D7197D7B2 CRC64;
MDGLLNPRES SKFIAENSRD VFIDSGGVRR VAELLLAKAA GPELRVEGWK ALHELNPRAA
DEAAVNWVFV TDTLNFSFWS EQDEHKCVVR YRGKTYSGYW SLCAAVNRAL DEGIPITSAS
YYATVTLDQV RNILRSDTDV SMPLVEERHR ILNETGKILL EKFGGSFLNC VRESENSAQK
LMHLVVESFP SYRDVTLFEG KRVSFYKRAQ ILVADTWSVL EGKGDGCFKD ISSITMFADY
RLPQVLAHLG ALKYSDDLLK KLLKGEMLSY GDRQEVEIRG CSLWCVELIR DCLLELIEQK
GEKPNGEINS ILLDYYLWDY AHDHREDMKG IPFHRIRCIY Y
//
MIM
611342
*RECORD*
*FIELD* NO
611342
*FIELD* TI
*611342 CHROMOSOME 9 OPEN READING FRAME 64; C9ORF64
*FIELD* TX
CLONING
By searching for genes in a region of chromosome 9q commonly deleted in
read moreacute myeloid leukemia (AML; 601626), followed by PCR of CD34
(142230)-positive bone marrow cells, Sweetser et al. (2005) cloned
C9ORF64. The deduced protein contains 289 amino acids.
GENE STRUCTURE
Sweetser et al. (2005) determined that the C9ORF64 gene contains 4
exons.
MAPPING
By genomic sequence analysis, Sweetser et al. (2005) mapped the C9ORF64
gene to chromosome 9q21.32
*FIELD* RF
1. Sweetser, D. A.; Peniket, A. J.; Haaland, C.; Blomberg, A. A.;
Zhang, Y.; Zaidi, S. T.; Dayyani, F.; Zhao, Z.; Heerema, N. A.; Boultwood,
J.; Dewald, G. W.; Paietta, E.; Slovak, M. L.; Willman, C. L.; Wainscoat,
J. S.; Bernstein, I. D.; Daly, S. B.: Delineation of the minimal
commonly deleted segment and identification of candidate tumor-suppressor
genes in del(9q) acute myeloid leukemia. Genes Chromosomes Cancer 44:
279-291, 2005.
*FIELD* CD
Patricia A. Hartz: 8/17/2007
*FIELD* ED
mgross: 08/17/2007
*RECORD*
*FIELD* NO
611342
*FIELD* TI
*611342 CHROMOSOME 9 OPEN READING FRAME 64; C9ORF64
*FIELD* TX
CLONING
By searching for genes in a region of chromosome 9q commonly deleted in
read moreacute myeloid leukemia (AML; 601626), followed by PCR of CD34
(142230)-positive bone marrow cells, Sweetser et al. (2005) cloned
C9ORF64. The deduced protein contains 289 amino acids.
GENE STRUCTURE
Sweetser et al. (2005) determined that the C9ORF64 gene contains 4
exons.
MAPPING
By genomic sequence analysis, Sweetser et al. (2005) mapped the C9ORF64
gene to chromosome 9q21.32
*FIELD* RF
1. Sweetser, D. A.; Peniket, A. J.; Haaland, C.; Blomberg, A. A.;
Zhang, Y.; Zaidi, S. T.; Dayyani, F.; Zhao, Z.; Heerema, N. A.; Boultwood,
J.; Dewald, G. W.; Paietta, E.; Slovak, M. L.; Willman, C. L.; Wainscoat,
J. S.; Bernstein, I. D.; Daly, S. B.: Delineation of the minimal
commonly deleted segment and identification of candidate tumor-suppressor
genes in del(9q) acute myeloid leukemia. Genes Chromosomes Cancer 44:
279-291, 2005.
*FIELD* CD
Patricia A. Hartz: 8/17/2007
*FIELD* ED
mgross: 08/17/2007