Full text data of DAPL1
DAPL1
(EEDA)
[Confidence: low (only semi-automatic identification from reviews)]
Death-associated protein-like 1 (Early epithelial differentiation-associated protein)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Death-associated protein-like 1 (Early epithelial differentiation-associated protein)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
A0PJW8
ID DAPL1_HUMAN Reviewed; 107 AA.
AC A0PJW8; A0PJW9; B9EIK6;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
read moreDT 05-FEB-2008, sequence version 2.
DT 22-JAN-2014, entry version 48.
DE RecName: Full=Death-associated protein-like 1;
DE AltName: Full=Early epithelial differentiation-associated protein;
GN Name=DAPL1; Synonyms=EEDA;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND VARIANT PRO-60.
RA Schulz H.L., Stojic J., Weber B.H.F.;
RT "Cloning and characterization of DAPL1.";
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT PRO-60.
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP TISSUE SPECIFICITY.
RC TISSUE=Corneal epithelium;
RX PubMed=15920738; DOI=10.1002/jcp.20433;
RA Sun L., Ryan D.G., Zhou M., Sun T.-T., Lavker R.M.;
RT "EEDA: a protein associated with an early stage of stratified
RT epithelial differentiation.";
RL J. Cell. Physiol. 206:103-111(2006).
CC -!- FUNCTION: May play a role in the early stages of epithelial
CC differentiation or in apoptosis (By similarity).
CC -!- TISSUE SPECIFICITY: Expressed in hair follicle (at protein level).
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
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DR EMBL; AY324399; AAQ93012.1; -; mRNA.
DR EMBL; CH471058; EAX11424.1; -; Genomic_DNA.
DR EMBL; BC127682; AAI27683.1; -; mRNA.
DR EMBL; BC127683; AAI27684.1; -; mRNA.
DR EMBL; BC140719; AAI40720.1; -; mRNA.
DR RefSeq; NP_001017920.2; NM_001017920.2.
DR UniGene; Hs.59761; -.
DR ProteinModelPortal; A0PJW8; -.
DR PhosphoSite; A0PJW8; -.
DR PaxDb; A0PJW8; -.
DR PRIDE; A0PJW8; -.
DR Ensembl; ENST00000309950; ENSP00000309538; ENSG00000163331.
DR GeneID; 92196; -.
DR KEGG; hsa:92196; -.
DR UCSC; uc002uaf.3; human.
DR CTD; 92196; -.
DR GeneCards; GC02P159651; -.
DR HGNC; HGNC:21490; DAPL1.
DR HPA; HPA046937; -.
DR neXtProt; NX_A0PJW8; -.
DR PharmGKB; PA134982815; -.
DR eggNOG; NOG84283; -.
DR HOGENOM; HOG000039719; -.
DR HOVERGEN; HBG005451; -.
DR OMA; LSHKFPA; -.
DR OrthoDB; EOG7RZ5SD; -.
DR PhylomeDB; A0PJW8; -.
DR GenomeRNAi; 92196; -.
DR NextBio; 77630; -.
DR PRO; PR:A0PJW8; -.
DR ArrayExpress; A0PJW8; -.
DR Bgee; A0PJW8; -.
DR CleanEx; HS_DAPL1; -.
DR Genevestigator; A0PJW8; -.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR InterPro; IPR024130; DAP1/DAPL1.
DR PANTHER; PTHR13177; PTHR13177; 1.
PE 1: Evidence at protein level;
KW Apoptosis; Complete proteome; Differentiation; Polymorphism;
KW Reference proteome.
FT CHAIN 1 107 Death-associated protein-like 1.
FT /FTId=PRO_0000316835.
FT VARIANT 60 60 L -> P (in dbSNP:rs9869).
FT /FTId=VAR_038402.
FT VARIANT 66 66 A -> T (in dbSNP:rs10497199).
FT /FTId=VAR_038403.
SQ SEQUENCE 107 AA; 11880 MW; 2BB99D8DEB3FC7C3 CRC64;
MANEVQDLLS PRKGGHPPAV KAGGMRISKK QEIGTLERHT KKTGFEKTSA IANVAKIQTL
DALNDALEKL NYKFPATVHM AHQKPTPALE KVVPLKRIYI IQQPRKC
//
ID DAPL1_HUMAN Reviewed; 107 AA.
AC A0PJW8; A0PJW9; B9EIK6;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
read moreDT 05-FEB-2008, sequence version 2.
DT 22-JAN-2014, entry version 48.
DE RecName: Full=Death-associated protein-like 1;
DE AltName: Full=Early epithelial differentiation-associated protein;
GN Name=DAPL1; Synonyms=EEDA;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND VARIANT PRO-60.
RA Schulz H.L., Stojic J., Weber B.H.F.;
RT "Cloning and characterization of DAPL1.";
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT PRO-60.
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP TISSUE SPECIFICITY.
RC TISSUE=Corneal epithelium;
RX PubMed=15920738; DOI=10.1002/jcp.20433;
RA Sun L., Ryan D.G., Zhou M., Sun T.-T., Lavker R.M.;
RT "EEDA: a protein associated with an early stage of stratified
RT epithelial differentiation.";
RL J. Cell. Physiol. 206:103-111(2006).
CC -!- FUNCTION: May play a role in the early stages of epithelial
CC differentiation or in apoptosis (By similarity).
CC -!- TISSUE SPECIFICITY: Expressed in hair follicle (at protein level).
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AY324399; AAQ93012.1; -; mRNA.
DR EMBL; CH471058; EAX11424.1; -; Genomic_DNA.
DR EMBL; BC127682; AAI27683.1; -; mRNA.
DR EMBL; BC127683; AAI27684.1; -; mRNA.
DR EMBL; BC140719; AAI40720.1; -; mRNA.
DR RefSeq; NP_001017920.2; NM_001017920.2.
DR UniGene; Hs.59761; -.
DR ProteinModelPortal; A0PJW8; -.
DR PhosphoSite; A0PJW8; -.
DR PaxDb; A0PJW8; -.
DR PRIDE; A0PJW8; -.
DR Ensembl; ENST00000309950; ENSP00000309538; ENSG00000163331.
DR GeneID; 92196; -.
DR KEGG; hsa:92196; -.
DR UCSC; uc002uaf.3; human.
DR CTD; 92196; -.
DR GeneCards; GC02P159651; -.
DR HGNC; HGNC:21490; DAPL1.
DR HPA; HPA046937; -.
DR neXtProt; NX_A0PJW8; -.
DR PharmGKB; PA134982815; -.
DR eggNOG; NOG84283; -.
DR HOGENOM; HOG000039719; -.
DR HOVERGEN; HBG005451; -.
DR OMA; LSHKFPA; -.
DR OrthoDB; EOG7RZ5SD; -.
DR PhylomeDB; A0PJW8; -.
DR GenomeRNAi; 92196; -.
DR NextBio; 77630; -.
DR PRO; PR:A0PJW8; -.
DR ArrayExpress; A0PJW8; -.
DR Bgee; A0PJW8; -.
DR CleanEx; HS_DAPL1; -.
DR Genevestigator; A0PJW8; -.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR InterPro; IPR024130; DAP1/DAPL1.
DR PANTHER; PTHR13177; PTHR13177; 1.
PE 1: Evidence at protein level;
KW Apoptosis; Complete proteome; Differentiation; Polymorphism;
KW Reference proteome.
FT CHAIN 1 107 Death-associated protein-like 1.
FT /FTId=PRO_0000316835.
FT VARIANT 60 60 L -> P (in dbSNP:rs9869).
FT /FTId=VAR_038402.
FT VARIANT 66 66 A -> T (in dbSNP:rs10497199).
FT /FTId=VAR_038403.
SQ SEQUENCE 107 AA; 11880 MW; 2BB99D8DEB3FC7C3 CRC64;
MANEVQDLLS PRKGGHPPAV KAGGMRISKK QEIGTLERHT KKTGFEKTSA IANVAKIQTL
DALNDALEKL NYKFPATVHM AHQKPTPALE KVVPLKRIYI IQQPRKC
//