Full text data of FAM49B
FAM49B
[Confidence: low (only semi-automatic identification from reviews)]
Protein FAM49B (L1)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Protein FAM49B (L1)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q9NUQ9
ID FA49B_HUMAN Reviewed; 324 AA.
AC Q9NUQ9; Q96AZ5; Q9NZE7;
DT 27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-OCT-2000, sequence version 1.
DT 22-JAN-2014, entry version 90.
DE RecName: Full=Protein FAM49B;
DE AltName: Full=L1;
GN Name=FAM49B; ORFNames=BM-009;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Bone marrow;
RX PubMed=11042152; DOI=10.1101/gr.140200;
RA Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G.,
RA Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W.,
RA Tao J., Huang Q.-H., Zhou J., Hu G.-X., Gu J., Chen S.-J., Chen Z.;
RT "Cloning and functional analysis of cDNAs with open reading frames for
RT 300 previously undefined genes expressed in CD34+ hematopoietic
RT stem/progenitor cells.";
RL Genome Res. 10:1546-1560(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], AND VARIANT LYS-169.
RA Petroziello J., Carter P.;
RT "Expression profiling in NSCLC.";
RL Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Placenta;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT LYS-169.
RC TISSUE=Brain, Kidney, and Lung;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- SIMILARITY: Belongs to the FAM49 family.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF64265.1; Type=Frameshift; Positions=65, 90, 126, 169, 172, 252, 292;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AF208851; AAF64265.1; ALT_FRAME; mRNA.
DR EMBL; AY598320; AAT06731.1; -; mRNA.
DR EMBL; AK002059; BAA92062.1; -; mRNA.
DR EMBL; BC003599; AAH03599.1; -; mRNA.
DR EMBL; BC016345; AAH16345.1; -; mRNA.
DR EMBL; BC017297; AAH17297.1; -; mRNA.
DR RefSeq; NP_001243692.1; NM_001256763.1.
DR RefSeq; NP_057707.3; NM_016623.4.
DR UniGene; Hs.126941; -.
DR ProteinModelPortal; Q9NUQ9; -.
DR IntAct; Q9NUQ9; 1.
DR MINT; MINT-2819889; -.
DR STRING; 9606.ENSP00000350710; -.
DR PhosphoSite; Q9NUQ9; -.
DR DMDM; 52782794; -.
DR PaxDb; Q9NUQ9; -.
DR PeptideAtlas; Q9NUQ9; -.
DR PRIDE; Q9NUQ9; -.
DR DNASU; 51571; -.
DR Ensembl; ENST00000401979; ENSP00000384880; ENSG00000153310.
DR Ensembl; ENST00000517654; ENSP00000430674; ENSG00000153310.
DR Ensembl; ENST00000519110; ENSP00000429078; ENSG00000153310.
DR Ensembl; ENST00000519540; ENSP00000429499; ENSG00000153310.
DR Ensembl; ENST00000519824; ENSP00000429150; ENSG00000153310.
DR Ensembl; ENST00000522746; ENSP00000428117; ENSG00000153310.
DR Ensembl; ENST00000523509; ENSP00000429802; ENSG00000153310.
DR GeneID; 51571; -.
DR KEGG; hsa:51571; -.
DR UCSC; uc003yss.4; human.
DR CTD; 51571; -.
DR GeneCards; GC08M130853; -.
DR H-InvDB; HIX0007786; -.
DR HGNC; HGNC:25216; FAM49B.
DR HPA; HPA009076; -.
DR neXtProt; NX_Q9NUQ9; -.
DR PharmGKB; PA134990565; -.
DR eggNOG; NOG301387; -.
DR HOGENOM; HOG000007560; -.
DR HOVERGEN; HBG057586; -.
DR InParanoid; Q9NUQ9; -.
DR OMA; RDDSNCC; -.
DR OrthoDB; EOG7FXZZN; -.
DR PhylomeDB; Q9NUQ9; -.
DR GenomeRNAi; 51571; -.
DR NextBio; 55396; -.
DR PRO; PR:Q9NUQ9; -.
DR ArrayExpress; Q9NUQ9; -.
DR Bgee; Q9NUQ9; -.
DR CleanEx; HS_FAM49B; -.
DR Genevestigator; Q9NUQ9; -.
DR GO; GO:0005929; C:cilium; IEA:Ensembl.
DR InterPro; IPR009828; DUF1394.
DR PANTHER; PTHR12422; PTHR12422; 1.
DR Pfam; PF07159; DUF1394; 1.
PE 1: Evidence at protein level;
KW Complete proteome; Polymorphism; Reference proteome.
FT CHAIN 1 324 Protein FAM49B.
FT /FTId=PRO_0000187060.
FT VARIANT 169 169 N -> K.
FT /FTId=VAR_019704.
SQ SEQUENCE 324 AA; 36748 MW; EE370E3D170A6E38 CRC64;
MGNLLKVLTC TDLEQGPNFF LDFENAQPTE SEKEIYNQVN VVLKDAEGIL EDLQSYRGAG
HEIREAIQHP ADEKLQEKAW GAVVPLVGKL KKFYEFSQRL EAALRGLLGA LTSTPYSPTQ
HLEREQALAK QFAEILHFTL RFDELKMTNP AIQNDFSYYR RTLSRMRINN VPAEGENEVN
NELANRMSLF YAEATPMLKT LSDATTKFVS ENKNLPIENT TDCLSTMASV CRVMLETPEY
RSRFTNEETV SFCLRVMVGV IILYDHVHPV GAFAKTSKID MKGCIKVLKD QPPNSVEGLL
NALRYTTKHL NDETTSKQIK SMLQ
//
ID FA49B_HUMAN Reviewed; 324 AA.
AC Q9NUQ9; Q96AZ5; Q9NZE7;
DT 27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-OCT-2000, sequence version 1.
DT 22-JAN-2014, entry version 90.
DE RecName: Full=Protein FAM49B;
DE AltName: Full=L1;
GN Name=FAM49B; ORFNames=BM-009;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Bone marrow;
RX PubMed=11042152; DOI=10.1101/gr.140200;
RA Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G.,
RA Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W.,
RA Tao J., Huang Q.-H., Zhou J., Hu G.-X., Gu J., Chen S.-J., Chen Z.;
RT "Cloning and functional analysis of cDNAs with open reading frames for
RT 300 previously undefined genes expressed in CD34+ hematopoietic
RT stem/progenitor cells.";
RL Genome Res. 10:1546-1560(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], AND VARIANT LYS-169.
RA Petroziello J., Carter P.;
RT "Expression profiling in NSCLC.";
RL Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Placenta;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT LYS-169.
RC TISSUE=Brain, Kidney, and Lung;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- SIMILARITY: Belongs to the FAM49 family.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF64265.1; Type=Frameshift; Positions=65, 90, 126, 169, 172, 252, 292;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AF208851; AAF64265.1; ALT_FRAME; mRNA.
DR EMBL; AY598320; AAT06731.1; -; mRNA.
DR EMBL; AK002059; BAA92062.1; -; mRNA.
DR EMBL; BC003599; AAH03599.1; -; mRNA.
DR EMBL; BC016345; AAH16345.1; -; mRNA.
DR EMBL; BC017297; AAH17297.1; -; mRNA.
DR RefSeq; NP_001243692.1; NM_001256763.1.
DR RefSeq; NP_057707.3; NM_016623.4.
DR UniGene; Hs.126941; -.
DR ProteinModelPortal; Q9NUQ9; -.
DR IntAct; Q9NUQ9; 1.
DR MINT; MINT-2819889; -.
DR STRING; 9606.ENSP00000350710; -.
DR PhosphoSite; Q9NUQ9; -.
DR DMDM; 52782794; -.
DR PaxDb; Q9NUQ9; -.
DR PeptideAtlas; Q9NUQ9; -.
DR PRIDE; Q9NUQ9; -.
DR DNASU; 51571; -.
DR Ensembl; ENST00000401979; ENSP00000384880; ENSG00000153310.
DR Ensembl; ENST00000517654; ENSP00000430674; ENSG00000153310.
DR Ensembl; ENST00000519110; ENSP00000429078; ENSG00000153310.
DR Ensembl; ENST00000519540; ENSP00000429499; ENSG00000153310.
DR Ensembl; ENST00000519824; ENSP00000429150; ENSG00000153310.
DR Ensembl; ENST00000522746; ENSP00000428117; ENSG00000153310.
DR Ensembl; ENST00000523509; ENSP00000429802; ENSG00000153310.
DR GeneID; 51571; -.
DR KEGG; hsa:51571; -.
DR UCSC; uc003yss.4; human.
DR CTD; 51571; -.
DR GeneCards; GC08M130853; -.
DR H-InvDB; HIX0007786; -.
DR HGNC; HGNC:25216; FAM49B.
DR HPA; HPA009076; -.
DR neXtProt; NX_Q9NUQ9; -.
DR PharmGKB; PA134990565; -.
DR eggNOG; NOG301387; -.
DR HOGENOM; HOG000007560; -.
DR HOVERGEN; HBG057586; -.
DR InParanoid; Q9NUQ9; -.
DR OMA; RDDSNCC; -.
DR OrthoDB; EOG7FXZZN; -.
DR PhylomeDB; Q9NUQ9; -.
DR GenomeRNAi; 51571; -.
DR NextBio; 55396; -.
DR PRO; PR:Q9NUQ9; -.
DR ArrayExpress; Q9NUQ9; -.
DR Bgee; Q9NUQ9; -.
DR CleanEx; HS_FAM49B; -.
DR Genevestigator; Q9NUQ9; -.
DR GO; GO:0005929; C:cilium; IEA:Ensembl.
DR InterPro; IPR009828; DUF1394.
DR PANTHER; PTHR12422; PTHR12422; 1.
DR Pfam; PF07159; DUF1394; 1.
PE 1: Evidence at protein level;
KW Complete proteome; Polymorphism; Reference proteome.
FT CHAIN 1 324 Protein FAM49B.
FT /FTId=PRO_0000187060.
FT VARIANT 169 169 N -> K.
FT /FTId=VAR_019704.
SQ SEQUENCE 324 AA; 36748 MW; EE370E3D170A6E38 CRC64;
MGNLLKVLTC TDLEQGPNFF LDFENAQPTE SEKEIYNQVN VVLKDAEGIL EDLQSYRGAG
HEIREAIQHP ADEKLQEKAW GAVVPLVGKL KKFYEFSQRL EAALRGLLGA LTSTPYSPTQ
HLEREQALAK QFAEILHFTL RFDELKMTNP AIQNDFSYYR RTLSRMRINN VPAEGENEVN
NELANRMSLF YAEATPMLKT LSDATTKFVS ENKNLPIENT TDCLSTMASV CRVMLETPEY
RSRFTNEETV SFCLRVMVGV IILYDHVHPV GAFAKTSKID MKGCIKVLKD QPPNSVEGLL
NALRYTTKHL NDETTSKQIK SMLQ
//