Full text data of FAM63B
FAM63B
(KIAA1164)
[Confidence: low (only semi-automatic identification from reviews)]
Protein FAM63B
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Protein FAM63B
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q8NBR6
ID FA63B_HUMAN Reviewed; 621 AA.
AC Q8NBR6; B2RTT8; Q9ULQ6;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
read moreDT 22-JUL-2008, sequence version 2.
DT 22-JAN-2014, entry version 74.
DE RecName: Full=Protein FAM63B;
GN Name=FAM63B; Synonyms=KIAA1164;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-605 (ISOFORM 1).
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 231-621 (ISOFORM 2).
RC TISSUE=Brain;
RX PubMed=10574461; DOI=10.1093/dnares/6.5.329;
RA Hirosawa M., Nagase T., Ishikawa K., Kikuno R., Nomura N., Ohara O.;
RT "Characterization of cDNA clones selected by the GeneMark analysis
RT from size-fractionated cDNA libraries from human brain.";
RL DNA Res. 6:329-336(1999).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-94, AND MASS
RP SPECTROMETRY.
RC TISSUE=Cervix carcinoma;
RX PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA Elledge S.J., Gygi S.P.;
RT "A quantitative atlas of mitotic phosphorylation.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8NBR6-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8NBR6-2; Sequence=VSP_034719;
CC -!- SIMILARITY: Belongs to the FAM63 family.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAW77545.1; Type=Erroneous gene model prediction;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; CH471082; EAW77545.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CH471082; EAW77546.1; -; Genomic_DNA.
DR EMBL; BC140811; AAI40812.1; -; mRNA.
DR EMBL; BC144616; AAI44617.1; -; mRNA.
DR EMBL; AK075319; BAC11545.1; -; mRNA.
DR EMBL; AB032990; BAA86478.1; -; mRNA.
DR RefSeq; NP_001035540.1; NM_001040450.1.
DR RefSeq; NP_001035543.1; NM_001040453.1.
DR UniGene; Hs.591122; -.
DR ProteinModelPortal; Q8NBR6; -.
DR PhosphoSite; Q8NBR6; -.
DR DMDM; 205831477; -.
DR PaxDb; Q8NBR6; -.
DR PRIDE; Q8NBR6; -.
DR Ensembl; ENST00000450403; ENSP00000393231; ENSG00000128923.
DR Ensembl; ENST00000559228; ENSP00000452885; ENSG00000128923.
DR GeneID; 54629; -.
DR KEGG; hsa:54629; -.
DR UCSC; uc002afj.3; human.
DR CTD; 54629; -.
DR GeneCards; GC15P059063; -.
DR H-InvDB; HIX0012284; -.
DR HGNC; HGNC:26954; FAM63B.
DR HPA; HPA051103; -.
DR neXtProt; NX_Q8NBR6; -.
DR PharmGKB; PA142671873; -.
DR eggNOG; NOG307988; -.
DR HOGENOM; HOG000060219; -.
DR HOVERGEN; HBG102840; -.
DR InParanoid; Q8NBR6; -.
DR OMA; RGQYKVT; -.
DR OrthoDB; EOG7Q5HD8; -.
DR ChiTaRS; FAM63B; human.
DR GenomeRNAi; 54629; -.
DR NextBio; 57178; -.
DR PRO; PR:Q8NBR6; -.
DR ArrayExpress; Q8NBR6; -.
DR Bgee; Q8NBR6; -.
DR CleanEx; HS_FAM63B; -.
DR Genevestigator; Q8NBR6; -.
DR InterPro; IPR007518; DUF544.
DR PANTHER; PTHR18063; PTHR18063; 1.
DR Pfam; PF04424; DUF544; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Complete proteome; Phosphoprotein;
KW Reference proteome.
FT CHAIN 1 621 Protein FAM63B.
FT /FTId=PRO_0000344042.
FT COMPBIAS 508 585 Gln-rich.
FT MOD_RES 94 94 Phosphoserine.
FT VAR_SEQ 580 580 Missing (in isoform 2).
FT /FTId=VSP_034719.
SQ SEQUENCE 621 AA; 67106 MW; ED97D0BBCA6DC421 CRC64;
MESSPESLQP LEHGVAAGPA SGTGSSQEGL QETRLAAGDG PGVWAAETSG GNGLGAAAAR
RSLPDSASPA GSPEVPGPCS SSAGLDLKDS GLESPAAAEA PLRGQYKVTA SPETAVAGVG
HELGTAGDAG ARPDLAGTCQ AELTAAGSEE PSSAGGLSSS CSDPSPPGES PSLDSLESFS
NLHSFPSSCE FNSEEGAENR VPEEEEGAAV LPGAVPLCKE EEGEETAQVL AASKERFPGQ
SVYHIKWIQW KEENTPIITQ NENGPCPLLA ILNVLLLAWK VKLPPMMEII TAEQLMEYLG
DYMLDAKPKE ISEIQRLNYE QNMSDAMAIL HKLQTGLDVN VRFTGVRVFE YTPECIVFDL
LDIPLYHGWL VDPQIDDIVK AVGNCSYNQL VEKIISCKQS DNSELVSEGF VAEQFLNNTA
TQLTYHGLCE LTSTVQEGEL CVFFRNNHFS TMTKYKGQLY LLVTDQGFLT EEKVVWESLH
NVDGDGNFCD SEFHLRPPSD PETVYKGQQD QIDQDYLMAL SLQQEQQSQE INWEQIPEGI
SDLELAKKLQ EEEDRRASQY YQEQEQAAAA AAAASTQAQQ GQPAQASPSS GRQSGNSERK
RKEPREKDKE KEKEKNSCVI L
//
ID FA63B_HUMAN Reviewed; 621 AA.
AC Q8NBR6; B2RTT8; Q9ULQ6;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
read moreDT 22-JUL-2008, sequence version 2.
DT 22-JAN-2014, entry version 74.
DE RecName: Full=Protein FAM63B;
GN Name=FAM63B; Synonyms=KIAA1164;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-605 (ISOFORM 1).
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 231-621 (ISOFORM 2).
RC TISSUE=Brain;
RX PubMed=10574461; DOI=10.1093/dnares/6.5.329;
RA Hirosawa M., Nagase T., Ishikawa K., Kikuno R., Nomura N., Ohara O.;
RT "Characterization of cDNA clones selected by the GeneMark analysis
RT from size-fractionated cDNA libraries from human brain.";
RL DNA Res. 6:329-336(1999).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-94, AND MASS
RP SPECTROMETRY.
RC TISSUE=Cervix carcinoma;
RX PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA Elledge S.J., Gygi S.P.;
RT "A quantitative atlas of mitotic phosphorylation.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8NBR6-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8NBR6-2; Sequence=VSP_034719;
CC -!- SIMILARITY: Belongs to the FAM63 family.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAW77545.1; Type=Erroneous gene model prediction;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; CH471082; EAW77545.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CH471082; EAW77546.1; -; Genomic_DNA.
DR EMBL; BC140811; AAI40812.1; -; mRNA.
DR EMBL; BC144616; AAI44617.1; -; mRNA.
DR EMBL; AK075319; BAC11545.1; -; mRNA.
DR EMBL; AB032990; BAA86478.1; -; mRNA.
DR RefSeq; NP_001035540.1; NM_001040450.1.
DR RefSeq; NP_001035543.1; NM_001040453.1.
DR UniGene; Hs.591122; -.
DR ProteinModelPortal; Q8NBR6; -.
DR PhosphoSite; Q8NBR6; -.
DR DMDM; 205831477; -.
DR PaxDb; Q8NBR6; -.
DR PRIDE; Q8NBR6; -.
DR Ensembl; ENST00000450403; ENSP00000393231; ENSG00000128923.
DR Ensembl; ENST00000559228; ENSP00000452885; ENSG00000128923.
DR GeneID; 54629; -.
DR KEGG; hsa:54629; -.
DR UCSC; uc002afj.3; human.
DR CTD; 54629; -.
DR GeneCards; GC15P059063; -.
DR H-InvDB; HIX0012284; -.
DR HGNC; HGNC:26954; FAM63B.
DR HPA; HPA051103; -.
DR neXtProt; NX_Q8NBR6; -.
DR PharmGKB; PA142671873; -.
DR eggNOG; NOG307988; -.
DR HOGENOM; HOG000060219; -.
DR HOVERGEN; HBG102840; -.
DR InParanoid; Q8NBR6; -.
DR OMA; RGQYKVT; -.
DR OrthoDB; EOG7Q5HD8; -.
DR ChiTaRS; FAM63B; human.
DR GenomeRNAi; 54629; -.
DR NextBio; 57178; -.
DR PRO; PR:Q8NBR6; -.
DR ArrayExpress; Q8NBR6; -.
DR Bgee; Q8NBR6; -.
DR CleanEx; HS_FAM63B; -.
DR Genevestigator; Q8NBR6; -.
DR InterPro; IPR007518; DUF544.
DR PANTHER; PTHR18063; PTHR18063; 1.
DR Pfam; PF04424; DUF544; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Complete proteome; Phosphoprotein;
KW Reference proteome.
FT CHAIN 1 621 Protein FAM63B.
FT /FTId=PRO_0000344042.
FT COMPBIAS 508 585 Gln-rich.
FT MOD_RES 94 94 Phosphoserine.
FT VAR_SEQ 580 580 Missing (in isoform 2).
FT /FTId=VSP_034719.
SQ SEQUENCE 621 AA; 67106 MW; ED97D0BBCA6DC421 CRC64;
MESSPESLQP LEHGVAAGPA SGTGSSQEGL QETRLAAGDG PGVWAAETSG GNGLGAAAAR
RSLPDSASPA GSPEVPGPCS SSAGLDLKDS GLESPAAAEA PLRGQYKVTA SPETAVAGVG
HELGTAGDAG ARPDLAGTCQ AELTAAGSEE PSSAGGLSSS CSDPSPPGES PSLDSLESFS
NLHSFPSSCE FNSEEGAENR VPEEEEGAAV LPGAVPLCKE EEGEETAQVL AASKERFPGQ
SVYHIKWIQW KEENTPIITQ NENGPCPLLA ILNVLLLAWK VKLPPMMEII TAEQLMEYLG
DYMLDAKPKE ISEIQRLNYE QNMSDAMAIL HKLQTGLDVN VRFTGVRVFE YTPECIVFDL
LDIPLYHGWL VDPQIDDIVK AVGNCSYNQL VEKIISCKQS DNSELVSEGF VAEQFLNNTA
TQLTYHGLCE LTSTVQEGEL CVFFRNNHFS TMTKYKGQLY LLVTDQGFLT EEKVVWESLH
NVDGDGNFCD SEFHLRPPSD PETVYKGQQD QIDQDYLMAL SLQQEQQSQE INWEQIPEGI
SDLELAKKLQ EEEDRRASQY YQEQEQAAAA AAAASTQAQQ GQPAQASPSS GRQSGNSERK
RKEPREKDKE KEKEKNSCVI L
//