Full text data of FAM96A
FAM96A
[Confidence: low (only semi-automatic identification from reviews)]
MIP18 family protein FAM96A
Note: presumably soluble (membrane word is not in UniProt keywords or features)
MIP18 family protein FAM96A
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q9H5X1
ID FA96A_HUMAN Reviewed; 160 AA.
AC Q9H5X1; A6NKS1; B2R5F8; B7Z8Z5;
DT 02-MAY-2002, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAR-2001, sequence version 1.
DT 22-JAN-2014, entry version 88.
DE RecName: Full=MIP18 family protein FAM96A;
GN Name=FAM96A;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Brain, and Trachea;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16572171; DOI=10.1038/nature04601;
RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA Nusbaum C.;
RT "Analysis of the DNA sequence and duplication history of human
RT chromosome 15.";
RL Nature 440:671-675(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E.,
RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K.,
RA Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-
RT terminal acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
RN [7]
RP X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 31-157, SUBUNIT, SUBCELLULAR
RP LOCATION, ZINC-BINDING SITES, AND TISSUE SPECIFICITY.
RX PubMed=22683786; DOI=10.1107/S0907444912006592;
RA Chen K.E., Richards A.A., Ariffin J.K., Ross I.L., Sweet M.J.,
RA Kellie S., Kobe B., Martin J.L.;
RT "The mammalian DUF59 protein Fam96a forms two distinct types of
RT domain-swapped dimer.";
RL Acta Crystallogr. D 68:637-648(2012).
CC -!- FUNCTION: May play a role in chromosome segregation through
CC establishment of sister chromatid cohesion (By similarity).
CC -!- SUBUNIT: Monomer and homodimer. Interacts with CIAO1.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9H5X1-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9H5X1-2; Sequence=VSP_042683;
CC Note=No experimental confirmation available;
CC -!- TISSUE SPECIFICITY: Substantially enriched in macrophages.
CC -!- SIMILARITY: Belongs to the MIP18 family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AK026528; BAB15496.1; -; mRNA.
DR EMBL; AK304202; BAH14131.1; -; mRNA.
DR EMBL; AK312171; BAG35105.1; -; mRNA.
DR EMBL; AC021541; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471082; EAW77661.1; -; Genomic_DNA.
DR EMBL; CH471082; EAW77662.1; -; Genomic_DNA.
DR EMBL; BC008865; AAH08865.1; -; mRNA.
DR RefSeq; NP_001014812.1; NM_001014812.1.
DR RefSeq; NP_115607.1; NM_032231.4.
DR UniGene; Hs.439548; -.
DR PDB; 2M5H; NMR; -; A=28-160.
DR PDB; 3UX2; X-ray; 1.80 A; A=31-157.
DR PDB; 3UX3; X-ray; 1.80 A; A/B=31-157.
DR PDBsum; 2M5H; -.
DR PDBsum; 3UX2; -.
DR PDBsum; 3UX3; -.
DR ProteinModelPortal; Q9H5X1; -.
DR SMR; Q9H5X1; 31-157.
DR IntAct; Q9H5X1; 1.
DR MINT; MINT-1435495; -.
DR STRING; 9606.ENSP00000300030; -.
DR PhosphoSite; Q9H5X1; -.
DR DMDM; 20455359; -.
DR PaxDb; Q9H5X1; -.
DR PRIDE; Q9H5X1; -.
DR Ensembl; ENST00000300030; ENSP00000300030; ENSG00000166797.
DR Ensembl; ENST00000380290; ENSP00000369644; ENSG00000166797.
DR Ensembl; ENST00000557835; ENSP00000454079; ENSG00000166797.
DR GeneID; 84191; -.
DR KEGG; hsa:84191; -.
DR UCSC; uc002amt.1; human.
DR CTD; 84191; -.
DR GeneCards; GC15M064364; -.
DR H-InvDB; HIX0012334; -.
DR HGNC; HGNC:26235; FAM96A.
DR HPA; HPA040459; -.
DR neXtProt; NX_Q9H5X1; -.
DR PharmGKB; PA142671829; -.
DR eggNOG; COG5133; -.
DR HOGENOM; HOG000157065; -.
DR HOVERGEN; HBG029509; -.
DR InParanoid; Q9H5X1; -.
DR OMA; QVKLQRC; -.
DR OrthoDB; EOG7034J5; -.
DR PhylomeDB; Q9H5X1; -.
DR ChiTaRS; FAM96A; human.
DR GenomeRNAi; 84191; -.
DR NextBio; 73586; -.
DR PRO; PR:Q9H5X1; -.
DR ArrayExpress; Q9H5X1; -.
DR Bgee; Q9H5X1; -.
DR CleanEx; HS_FAM96A; -.
DR Genevestigator; Q9H5X1; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR InterPro; IPR002744; DUF59.
DR Pfam; PF01883; DUF59; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Alternative splicing; Chromosome partition;
KW Complete proteome; Cytoplasm; Metal-binding; Reference proteome; Zinc.
FT CHAIN 1 160 MIP18 family protein FAM96A.
FT /FTId=PRO_0000212689.
FT METAL 89 89 Zinc 1; shared with dimeric partner.
FT METAL 89 89 Zinc 2; shared with dimeric partner.
FT METAL 123 123 Zinc 1; shared with dimeric partner.
FT METAL 123 123 Zinc 2; shared with dimeric partner.
FT METAL 150 150 Zinc 1; shared with dimeric partner.
FT METAL 150 150 Zinc 2; shared with dimeric partner.
FT METAL 153 153 Zinc 1; shared with dimeric partner.
FT METAL 153 153 Zinc 2; shared with dimeric partner.
FT VAR_SEQ 97 160 GLCLRVKLQRCLPFKHKLEIYISEGTHSTEEDINKQINDKE
FT RVAAAMENPNLREIVEQCVLEPD -> VGNLHF (in
FT isoform 2).
FT /FTId=VSP_042683.
FT HELIX 31 44
FT STRAND 50 55
FT TURN 56 60
FT HELIX 64 66
FT STRAND 67 73
FT STRAND 76 81
FT STRAND 86 88
FT HELIX 92 107
FT STRAND 112 120
FT STRAND 122 124
FT HELIX 129 134
FT HELIX 136 144
FT HELIX 146 156
SQ SEQUENCE 160 AA; 18355 MW; 8580E4E397067319 CRC64;
MQRVSGLLSW TLSRVLWLSG LSEPGAARQP RIMEEKALEV YDLIRTIRDP EKPNTLEELE
VVSESCVEVQ EINEEEYLVI IRFTPTVPHC SLATLIGLCL RVKLQRCLPF KHKLEIYISE
GTHSTEEDIN KQINDKERVA AAMENPNLRE IVEQCVLEPD
//
ID FA96A_HUMAN Reviewed; 160 AA.
AC Q9H5X1; A6NKS1; B2R5F8; B7Z8Z5;
DT 02-MAY-2002, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAR-2001, sequence version 1.
DT 22-JAN-2014, entry version 88.
DE RecName: Full=MIP18 family protein FAM96A;
GN Name=FAM96A;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Brain, and Trachea;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16572171; DOI=10.1038/nature04601;
RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA Nusbaum C.;
RT "Analysis of the DNA sequence and duplication history of human
RT chromosome 15.";
RL Nature 440:671-675(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E.,
RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K.,
RA Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-
RT terminal acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
RN [7]
RP X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 31-157, SUBUNIT, SUBCELLULAR
RP LOCATION, ZINC-BINDING SITES, AND TISSUE SPECIFICITY.
RX PubMed=22683786; DOI=10.1107/S0907444912006592;
RA Chen K.E., Richards A.A., Ariffin J.K., Ross I.L., Sweet M.J.,
RA Kellie S., Kobe B., Martin J.L.;
RT "The mammalian DUF59 protein Fam96a forms two distinct types of
RT domain-swapped dimer.";
RL Acta Crystallogr. D 68:637-648(2012).
CC -!- FUNCTION: May play a role in chromosome segregation through
CC establishment of sister chromatid cohesion (By similarity).
CC -!- SUBUNIT: Monomer and homodimer. Interacts with CIAO1.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9H5X1-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9H5X1-2; Sequence=VSP_042683;
CC Note=No experimental confirmation available;
CC -!- TISSUE SPECIFICITY: Substantially enriched in macrophages.
CC -!- SIMILARITY: Belongs to the MIP18 family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AK026528; BAB15496.1; -; mRNA.
DR EMBL; AK304202; BAH14131.1; -; mRNA.
DR EMBL; AK312171; BAG35105.1; -; mRNA.
DR EMBL; AC021541; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471082; EAW77661.1; -; Genomic_DNA.
DR EMBL; CH471082; EAW77662.1; -; Genomic_DNA.
DR EMBL; BC008865; AAH08865.1; -; mRNA.
DR RefSeq; NP_001014812.1; NM_001014812.1.
DR RefSeq; NP_115607.1; NM_032231.4.
DR UniGene; Hs.439548; -.
DR PDB; 2M5H; NMR; -; A=28-160.
DR PDB; 3UX2; X-ray; 1.80 A; A=31-157.
DR PDB; 3UX3; X-ray; 1.80 A; A/B=31-157.
DR PDBsum; 2M5H; -.
DR PDBsum; 3UX2; -.
DR PDBsum; 3UX3; -.
DR ProteinModelPortal; Q9H5X1; -.
DR SMR; Q9H5X1; 31-157.
DR IntAct; Q9H5X1; 1.
DR MINT; MINT-1435495; -.
DR STRING; 9606.ENSP00000300030; -.
DR PhosphoSite; Q9H5X1; -.
DR DMDM; 20455359; -.
DR PaxDb; Q9H5X1; -.
DR PRIDE; Q9H5X1; -.
DR Ensembl; ENST00000300030; ENSP00000300030; ENSG00000166797.
DR Ensembl; ENST00000380290; ENSP00000369644; ENSG00000166797.
DR Ensembl; ENST00000557835; ENSP00000454079; ENSG00000166797.
DR GeneID; 84191; -.
DR KEGG; hsa:84191; -.
DR UCSC; uc002amt.1; human.
DR CTD; 84191; -.
DR GeneCards; GC15M064364; -.
DR H-InvDB; HIX0012334; -.
DR HGNC; HGNC:26235; FAM96A.
DR HPA; HPA040459; -.
DR neXtProt; NX_Q9H5X1; -.
DR PharmGKB; PA142671829; -.
DR eggNOG; COG5133; -.
DR HOGENOM; HOG000157065; -.
DR HOVERGEN; HBG029509; -.
DR InParanoid; Q9H5X1; -.
DR OMA; QVKLQRC; -.
DR OrthoDB; EOG7034J5; -.
DR PhylomeDB; Q9H5X1; -.
DR ChiTaRS; FAM96A; human.
DR GenomeRNAi; 84191; -.
DR NextBio; 73586; -.
DR PRO; PR:Q9H5X1; -.
DR ArrayExpress; Q9H5X1; -.
DR Bgee; Q9H5X1; -.
DR CleanEx; HS_FAM96A; -.
DR Genevestigator; Q9H5X1; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR InterPro; IPR002744; DUF59.
DR Pfam; PF01883; DUF59; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Alternative splicing; Chromosome partition;
KW Complete proteome; Cytoplasm; Metal-binding; Reference proteome; Zinc.
FT CHAIN 1 160 MIP18 family protein FAM96A.
FT /FTId=PRO_0000212689.
FT METAL 89 89 Zinc 1; shared with dimeric partner.
FT METAL 89 89 Zinc 2; shared with dimeric partner.
FT METAL 123 123 Zinc 1; shared with dimeric partner.
FT METAL 123 123 Zinc 2; shared with dimeric partner.
FT METAL 150 150 Zinc 1; shared with dimeric partner.
FT METAL 150 150 Zinc 2; shared with dimeric partner.
FT METAL 153 153 Zinc 1; shared with dimeric partner.
FT METAL 153 153 Zinc 2; shared with dimeric partner.
FT VAR_SEQ 97 160 GLCLRVKLQRCLPFKHKLEIYISEGTHSTEEDINKQINDKE
FT RVAAAMENPNLREIVEQCVLEPD -> VGNLHF (in
FT isoform 2).
FT /FTId=VSP_042683.
FT HELIX 31 44
FT STRAND 50 55
FT TURN 56 60
FT HELIX 64 66
FT STRAND 67 73
FT STRAND 76 81
FT STRAND 86 88
FT HELIX 92 107
FT STRAND 112 120
FT STRAND 122 124
FT HELIX 129 134
FT HELIX 136 144
FT HELIX 146 156
SQ SEQUENCE 160 AA; 18355 MW; 8580E4E397067319 CRC64;
MQRVSGLLSW TLSRVLWLSG LSEPGAARQP RIMEEKALEV YDLIRTIRDP EKPNTLEELE
VVSESCVEVQ EINEEEYLVI IRFTPTVPHC SLATLIGLCL RVKLQRCLPF KHKLEIYISE
GTHSTEEDIN KQINDKERVA AAMENPNLRE IVEQCVLEPD
//