Full text data of GLTPD2
GLTPD2
[Confidence: low (only semi-automatic identification from reviews)]
Glycolipid transfer protein domain-containing protein 2
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Glycolipid transfer protein domain-containing protein 2
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
A6NH11
ID GLTD2_HUMAN Reviewed; 291 AA.
AC A6NH11; A7E2T2;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
read moreDT 31-MAY-2011, sequence version 2.
DT 22-JAN-2014, entry version 49.
DE RecName: Full=Glycolipid transfer protein domain-containing protein 2;
GN Name=GLTPD2;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT the human lineage.";
RL Nature 440:1045-1049(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 70-291.
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-276, AND MASS
RP SPECTROMETRY.
RC TISSUE=Liver;
RX PubMed=19159218; DOI=10.1021/pr8008012;
RA Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.;
RT "Glycoproteomics analysis of human liver tissue by combination of
RT multiple enzyme digestion and hydrazide chemistry.";
RL J. Proteome Res. 8:651-661(2009).
CC -!- SIMILARITY: Belongs to the GLTP family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AC109333; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC150536; AAI50537.1; -; mRNA.
DR UniGene; Hs.131035; -.
DR ProteinModelPortal; A6NH11; -.
DR IntAct; A6NH11; 1.
DR STRING; 9606.ENSP00000328070; -.
DR PhosphoSite; A6NH11; -.
DR PaxDb; A6NH11; -.
DR PRIDE; A6NH11; -.
DR Ensembl; ENST00000331264; ENSP00000328070; ENSG00000182327.
DR UCSC; uc002fza.2; human.
DR GeneCards; GC17P004692; -.
DR H-InvDB; HIX0013449; -.
DR H-InvDB; HIX0135615; -.
DR HGNC; HGNC:33756; GLTPD2.
DR neXtProt; NX_A6NH11; -.
DR PharmGKB; PA162389864; -.
DR eggNOG; NOG306612; -.
DR HOGENOM; HOG000046738; -.
DR HOVERGEN; HBG100515; -.
DR InParanoid; A6NH11; -.
DR OMA; LCLHRVA; -.
DR OrthoDB; EOG7BW0MQ; -.
DR NextBio; 21544936; -.
DR PRO; PR:A6NH11; -.
DR Bgee; A6NH11; -.
DR CleanEx; HS_GLTPD2; -.
DR Genevestigator; A6NH11; -.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0051861; F:glycolipid binding; IEA:InterPro.
DR GO; GO:0017089; F:glycolipid transporter activity; IEA:InterPro.
DR GO; GO:0046836; P:glycolipid transport; IEA:InterPro.
DR Gene3D; 1.10.3520.10; -; 1.
DR InterPro; IPR014830; Glycolipid_transfer_prot_dom.
DR Pfam; PF08718; GLTP; 1.
DR SUPFAM; SSF110004; SSF110004; 1.
PE 1: Evidence at protein level;
KW Complete proteome; Glycoprotein; Reference proteome.
FT CHAIN 1 291 Glycolipid transfer protein domain-
FT containing protein 2.
FT /FTId=PRO_0000317162.
FT CARBOHYD 276 276 N-linked (GlcNAc...).
FT CONFLICT 152 152 V -> A (in Ref. 2; AAI50537).
FT CONFLICT 209 209 D -> E (in Ref. 2; AAI50537).
FT CONFLICT 265 265 V -> L (in Ref. 2; AAI50537).
SQ SEQUENCE 291 AA; 31642 MW; 589565F42C5AA13F CRC64;
MGVAARPPAL RHWFSHSIPL AIFALLLLYL SVRSLGARSG CGPRAQPCVP GETAPFQVRQ
ESGTLEAPER KQPPCLGPRG MLGRMMRRFH ASLKPEGDVG LSPYLAGWRA LVEFLTPLGS
VFAFATREAF TKVTDLEARV HGPDAEHYWS LVAMAAWERR AGLLEQPGAA PRDPTRSSGS
RTLLLLHRAL RWSQLCLHRV ATGALGGPDA GVQCSDAYRA ALGPHHPWLV RQTARLAFLA
FPGRRRLLEL ACPGATEAEA RAALVRAAGT LEDVYNRTQS LLAERGLLQL A
//
ID GLTD2_HUMAN Reviewed; 291 AA.
AC A6NH11; A7E2T2;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
read moreDT 31-MAY-2011, sequence version 2.
DT 22-JAN-2014, entry version 49.
DE RecName: Full=Glycolipid transfer protein domain-containing protein 2;
GN Name=GLTPD2;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT the human lineage.";
RL Nature 440:1045-1049(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 70-291.
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-276, AND MASS
RP SPECTROMETRY.
RC TISSUE=Liver;
RX PubMed=19159218; DOI=10.1021/pr8008012;
RA Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.;
RT "Glycoproteomics analysis of human liver tissue by combination of
RT multiple enzyme digestion and hydrazide chemistry.";
RL J. Proteome Res. 8:651-661(2009).
CC -!- SIMILARITY: Belongs to the GLTP family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AC109333; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC150536; AAI50537.1; -; mRNA.
DR UniGene; Hs.131035; -.
DR ProteinModelPortal; A6NH11; -.
DR IntAct; A6NH11; 1.
DR STRING; 9606.ENSP00000328070; -.
DR PhosphoSite; A6NH11; -.
DR PaxDb; A6NH11; -.
DR PRIDE; A6NH11; -.
DR Ensembl; ENST00000331264; ENSP00000328070; ENSG00000182327.
DR UCSC; uc002fza.2; human.
DR GeneCards; GC17P004692; -.
DR H-InvDB; HIX0013449; -.
DR H-InvDB; HIX0135615; -.
DR HGNC; HGNC:33756; GLTPD2.
DR neXtProt; NX_A6NH11; -.
DR PharmGKB; PA162389864; -.
DR eggNOG; NOG306612; -.
DR HOGENOM; HOG000046738; -.
DR HOVERGEN; HBG100515; -.
DR InParanoid; A6NH11; -.
DR OMA; LCLHRVA; -.
DR OrthoDB; EOG7BW0MQ; -.
DR NextBio; 21544936; -.
DR PRO; PR:A6NH11; -.
DR Bgee; A6NH11; -.
DR CleanEx; HS_GLTPD2; -.
DR Genevestigator; A6NH11; -.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0051861; F:glycolipid binding; IEA:InterPro.
DR GO; GO:0017089; F:glycolipid transporter activity; IEA:InterPro.
DR GO; GO:0046836; P:glycolipid transport; IEA:InterPro.
DR Gene3D; 1.10.3520.10; -; 1.
DR InterPro; IPR014830; Glycolipid_transfer_prot_dom.
DR Pfam; PF08718; GLTP; 1.
DR SUPFAM; SSF110004; SSF110004; 1.
PE 1: Evidence at protein level;
KW Complete proteome; Glycoprotein; Reference proteome.
FT CHAIN 1 291 Glycolipid transfer protein domain-
FT containing protein 2.
FT /FTId=PRO_0000317162.
FT CARBOHYD 276 276 N-linked (GlcNAc...).
FT CONFLICT 152 152 V -> A (in Ref. 2; AAI50537).
FT CONFLICT 209 209 D -> E (in Ref. 2; AAI50537).
FT CONFLICT 265 265 V -> L (in Ref. 2; AAI50537).
SQ SEQUENCE 291 AA; 31642 MW; 589565F42C5AA13F CRC64;
MGVAARPPAL RHWFSHSIPL AIFALLLLYL SVRSLGARSG CGPRAQPCVP GETAPFQVRQ
ESGTLEAPER KQPPCLGPRG MLGRMMRRFH ASLKPEGDVG LSPYLAGWRA LVEFLTPLGS
VFAFATREAF TKVTDLEARV HGPDAEHYWS LVAMAAWERR AGLLEQPGAA PRDPTRSSGS
RTLLLLHRAL RWSQLCLHRV ATGALGGPDA GVQCSDAYRA ALGPHHPWLV RQTARLAFLA
FPGRRRLLEL ACPGATEAEA RAALVRAAGT LEDVYNRTQS LLAERGLLQL A
//