Full text data of SORD
SORD
[Confidence: medium (present in either hRBCD or BSc_CH or PM22954596)]
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
H0YLA4
ID H0YLA4_HUMAN Unreviewed; 336 AA.
AC H0YLA4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
read moreDT 16-OCT-2013, entry version 13.
DE SubName: Full=Sorbitol dehydrogenase;
GN Name=SORD;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16572171; DOI=10.1038/nature04601;
RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA Nusbaum C.;
RT "Analysis of the DNA sequence and duplication history of human
RT chromosome 15.";
RL Nature 440:671-675(2006).
RN [2]
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JAN-2012) to UniProtKB.
CC -!- COFACTOR: Zinc (By similarity).
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AC090888; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC091117; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR ProteinModelPortal; H0YLA4; -.
DR SMR; H0YLA4; 1-336.
DR Ensembl; ENST00000558580; ENSP00000453122; ENSG00000140263.
DR HGNC; HGNC:11184; SORD.
DR NextBio; 35524386; -.
DR ArrayExpress; H0YLA4; -.
DR Bgee; H0YLA4; -.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; -; 1.
DR Gene3D; 3.90.180.10; -; 1.
DR InterPro; IPR013149; ADH_C.
DR InterPro; IPR013154; ADH_GroES-like.
DR InterPro; IPR002085; ADH_SF_Zn-type.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR PANTHER; PTHR11695; PTHR11695; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; SSF50129; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 2: Evidence at transcript level;
KW Complete proteome; Metal-binding; Oxidoreductase; Reference proteome;
KW Zinc.
SQ SEQUENCE 336 AA; 36229 MW; 6B83DC8376E5162B CRC64;
MENYPIPEPG PNEVLLRMHS VGICGSDVHY WEYGRIGNFI VKKPMVLGHE ASGTVEKVGS
SVKHLKPGDR VAIEPGAPRE NDEFCKMGRY NLSPSIFFCA TPPDDGNLCR FYKHNAAFCY
KLPDNVTFEE GALIEPLSVG IHACRRGGVT LGHKVLVCGA GPIGMVTLLV AKAMGAAQVV
VTDLSATRLS KAKEIGADLV LQISKESPQE IARKVEGQLG CKPEVTIECT GAEASIQAGI
YATRSGGNLV LVGLGSEMTT VPLLHAAIRE VDIKGVFRYC NTWPVAISML ASKSVNVKPL
VTHRFPLEKA LEAFETFKKG LGLKIMLKCD PSDQNP
//
ID H0YLA4_HUMAN Unreviewed; 336 AA.
AC H0YLA4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
read moreDT 16-OCT-2013, entry version 13.
DE SubName: Full=Sorbitol dehydrogenase;
GN Name=SORD;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16572171; DOI=10.1038/nature04601;
RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA Nusbaum C.;
RT "Analysis of the DNA sequence and duplication history of human
RT chromosome 15.";
RL Nature 440:671-675(2006).
RN [2]
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JAN-2012) to UniProtKB.
CC -!- COFACTOR: Zinc (By similarity).
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AC090888; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC091117; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR ProteinModelPortal; H0YLA4; -.
DR SMR; H0YLA4; 1-336.
DR Ensembl; ENST00000558580; ENSP00000453122; ENSG00000140263.
DR HGNC; HGNC:11184; SORD.
DR NextBio; 35524386; -.
DR ArrayExpress; H0YLA4; -.
DR Bgee; H0YLA4; -.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; -; 1.
DR Gene3D; 3.90.180.10; -; 1.
DR InterPro; IPR013149; ADH_C.
DR InterPro; IPR013154; ADH_GroES-like.
DR InterPro; IPR002085; ADH_SF_Zn-type.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR PANTHER; PTHR11695; PTHR11695; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; SSF50129; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 2: Evidence at transcript level;
KW Complete proteome; Metal-binding; Oxidoreductase; Reference proteome;
KW Zinc.
SQ SEQUENCE 336 AA; 36229 MW; 6B83DC8376E5162B CRC64;
MENYPIPEPG PNEVLLRMHS VGICGSDVHY WEYGRIGNFI VKKPMVLGHE ASGTVEKVGS
SVKHLKPGDR VAIEPGAPRE NDEFCKMGRY NLSPSIFFCA TPPDDGNLCR FYKHNAAFCY
KLPDNVTFEE GALIEPLSVG IHACRRGGVT LGHKVLVCGA GPIGMVTLLV AKAMGAAQVV
VTDLSATRLS KAKEIGADLV LQISKESPQE IARKVEGQLG CKPEVTIECT GAEASIQAGI
YATRSGGNLV LVGLGSEMTT VPLLHAAIRE VDIKGVFRYC NTWPVAISML ASKSVNVKPL
VTHRFPLEKA LEAFETFKKG LGLKIMLKCD PSDQNP
//