Full text data of IRGQ
IRGQ
(IRGQ1)
[Confidence: low (only semi-automatic identification from reviews)]
Immunity-related GTPase family Q protein
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Immunity-related GTPase family Q protein
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q8WZA9
ID IRGQ_HUMAN Reviewed; 623 AA.
AC Q8WZA9; B2RNP3;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAR-2002, sequence version 1.
DT 22-JAN-2014, entry version 73.
DE RecName: Full=Immunity-related GTPase family Q protein;
GN Name=IRGQ; Synonyms=IRGQ1; ORFNames=FKSG27;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Wang Y.-G., Gong L.;
RT "Molecular cloning of FKSG27, a novel gene related to cervical
RT tumor.";
RL Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP PROTEIN SEQUENCE OF 2-20; 166-176; 178-214; 389-401; 533-544 AND
RP 596-609, AND MASS SPECTROMETRY.
RC TISSUE=Fetal brain cortex;
RA Lubec G., Chen W.-Q., Sun Y.;
RL Submitted (DEC-2008) to UniProtKB.
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-203, AND MASS
RP SPECTROMETRY.
RC TISSUE=Cervix carcinoma;
RX PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA Elledge S.J., Gygi S.P.;
RT "A quantitative atlas of mitotic phosphorylation.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
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DR EMBL; AF322648; AAL33884.1; -; mRNA.
DR EMBL; CH471126; EAW57205.1; -; Genomic_DNA.
DR EMBL; BC137020; AAI37021.1; -; mRNA.
DR EMBL; BC137021; AAI37022.1; -; mRNA.
DR RefSeq; NP_001007562.1; NM_001007561.2.
DR RefSeq; XP_005258572.1; XM_005258515.1.
DR RefSeq; XP_005258573.1; XM_005258516.1.
DR UniGene; Hs.6217; -.
DR ProteinModelPortal; Q8WZA9; -.
DR IntAct; Q8WZA9; 1.
DR STRING; 9606.ENSP00000300809; -.
DR PhosphoSite; Q8WZA9; -.
DR DMDM; 74751646; -.
DR PaxDb; Q8WZA9; -.
DR PeptideAtlas; Q8WZA9; -.
DR PRIDE; Q8WZA9; -.
DR Ensembl; ENST00000422989; ENSP00000387535; ENSG00000167378.
DR Ensembl; ENST00000602269; ENSP00000472250; ENSG00000167378.
DR GeneID; 126298; -.
DR KEGG; hsa:126298; -.
DR UCSC; uc002oww.2; human.
DR CTD; 126298; -.
DR GeneCards; GC19M044090; -.
DR HGNC; HGNC:24868; IRGQ.
DR HPA; HPA043254; -.
DR neXtProt; NX_Q8WZA9; -.
DR PharmGKB; PA142671653; -.
DR eggNOG; NOG46699; -.
DR HOGENOM; HOG000060088; -.
DR HOVERGEN; HBG081807; -.
DR InParanoid; Q8WZA9; -.
DR OMA; ALSFLWP; -.
DR OrthoDB; EOG7N37CM; -.
DR PhylomeDB; Q8WZA9; -.
DR ChiTaRS; IRGQ; human.
DR GenomeRNAi; 126298; -.
DR NextBio; 81757; -.
DR PRO; PR:Q8WZA9; -.
DR ArrayExpress; Q8WZA9; -.
DR Bgee; Q8WZA9; -.
DR CleanEx; HS_IRGQ; -.
DR Genevestigator; Q8WZA9; -.
PE 1: Evidence at protein level;
KW Coiled coil; Complete proteome; Direct protein sequencing;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1 623 Immunity-related GTPase family Q protein.
FT /FTId=PRO_0000264463.
FT COILED 155 180 Potential.
FT COMPBIAS 288 291 Poly-Ala.
FT COMPBIAS 358 361 Poly-Gly.
FT COMPBIAS 449 617 Ala-rich.
FT MOD_RES 203 203 Phosphothreonine.
SQ SEQUENCE 623 AA; 62717 MW; 6D7231134A3A799B CRC64;
MPPPQGDVTA LFLGPPGLGK SALIAALCDK DVETLEAPEG RPDSGVPSLR AAGPGLFLGE
LSCPPAAPGP WAAEANVLVL VLPGPEGNGE PLAPALGEAA LAALARGTPL LAVRNLRPGD
SQTAAQARDQ TAALLNSAGL GAADLFVLPA NCGSSDGCEE LERLRAALQS QAEALRRLLP
PAQDGFEVLG AAELEAVREA FETGGLEAAL SWVRSGLERL GSARLDLAVA GKADVGLVVD
MLLGLDPGDP GAAPASVPTA PTPFPAPERP NVVLWTVPLG HTGTATTAAA ASHPTHYDAL
ILVTPGAPTE KDWAQVQALL LPDAPLVCVR TDGEGEDPEC LGEGKMENPK GESLKNAGGG
GLENALSKGR EKCSAGSQKA GSGEGPGKAG SEGLQQVVGM KKSGGGDSER AAALSPEDET
WEVLEEAPPP VFPLRPGGLP GLCEWLRRAL PPAQAGALLL ALPPASPSAA RTKAAALRAG
AWRPALLASL AAAAAPLPGL GWACDVALLR GQLAEWRRGL GLEPTALARR ERALGLASGE
LAARAHFPGP VTRAEVEARL GAWAGEGTAG GAALGALSFL WPAGGAAATG GLGYRAAHGV
LLQALDEMRA DAEAVLAPPE PAQ
//
ID IRGQ_HUMAN Reviewed; 623 AA.
AC Q8WZA9; B2RNP3;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAR-2002, sequence version 1.
DT 22-JAN-2014, entry version 73.
DE RecName: Full=Immunity-related GTPase family Q protein;
GN Name=IRGQ; Synonyms=IRGQ1; ORFNames=FKSG27;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Wang Y.-G., Gong L.;
RT "Molecular cloning of FKSG27, a novel gene related to cervical
RT tumor.";
RL Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP PROTEIN SEQUENCE OF 2-20; 166-176; 178-214; 389-401; 533-544 AND
RP 596-609, AND MASS SPECTROMETRY.
RC TISSUE=Fetal brain cortex;
RA Lubec G., Chen W.-Q., Sun Y.;
RL Submitted (DEC-2008) to UniProtKB.
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-203, AND MASS
RP SPECTROMETRY.
RC TISSUE=Cervix carcinoma;
RX PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA Elledge S.J., Gygi S.P.;
RT "A quantitative atlas of mitotic phosphorylation.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AF322648; AAL33884.1; -; mRNA.
DR EMBL; CH471126; EAW57205.1; -; Genomic_DNA.
DR EMBL; BC137020; AAI37021.1; -; mRNA.
DR EMBL; BC137021; AAI37022.1; -; mRNA.
DR RefSeq; NP_001007562.1; NM_001007561.2.
DR RefSeq; XP_005258572.1; XM_005258515.1.
DR RefSeq; XP_005258573.1; XM_005258516.1.
DR UniGene; Hs.6217; -.
DR ProteinModelPortal; Q8WZA9; -.
DR IntAct; Q8WZA9; 1.
DR STRING; 9606.ENSP00000300809; -.
DR PhosphoSite; Q8WZA9; -.
DR DMDM; 74751646; -.
DR PaxDb; Q8WZA9; -.
DR PeptideAtlas; Q8WZA9; -.
DR PRIDE; Q8WZA9; -.
DR Ensembl; ENST00000422989; ENSP00000387535; ENSG00000167378.
DR Ensembl; ENST00000602269; ENSP00000472250; ENSG00000167378.
DR GeneID; 126298; -.
DR KEGG; hsa:126298; -.
DR UCSC; uc002oww.2; human.
DR CTD; 126298; -.
DR GeneCards; GC19M044090; -.
DR HGNC; HGNC:24868; IRGQ.
DR HPA; HPA043254; -.
DR neXtProt; NX_Q8WZA9; -.
DR PharmGKB; PA142671653; -.
DR eggNOG; NOG46699; -.
DR HOGENOM; HOG000060088; -.
DR HOVERGEN; HBG081807; -.
DR InParanoid; Q8WZA9; -.
DR OMA; ALSFLWP; -.
DR OrthoDB; EOG7N37CM; -.
DR PhylomeDB; Q8WZA9; -.
DR ChiTaRS; IRGQ; human.
DR GenomeRNAi; 126298; -.
DR NextBio; 81757; -.
DR PRO; PR:Q8WZA9; -.
DR ArrayExpress; Q8WZA9; -.
DR Bgee; Q8WZA9; -.
DR CleanEx; HS_IRGQ; -.
DR Genevestigator; Q8WZA9; -.
PE 1: Evidence at protein level;
KW Coiled coil; Complete proteome; Direct protein sequencing;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1 623 Immunity-related GTPase family Q protein.
FT /FTId=PRO_0000264463.
FT COILED 155 180 Potential.
FT COMPBIAS 288 291 Poly-Ala.
FT COMPBIAS 358 361 Poly-Gly.
FT COMPBIAS 449 617 Ala-rich.
FT MOD_RES 203 203 Phosphothreonine.
SQ SEQUENCE 623 AA; 62717 MW; 6D7231134A3A799B CRC64;
MPPPQGDVTA LFLGPPGLGK SALIAALCDK DVETLEAPEG RPDSGVPSLR AAGPGLFLGE
LSCPPAAPGP WAAEANVLVL VLPGPEGNGE PLAPALGEAA LAALARGTPL LAVRNLRPGD
SQTAAQARDQ TAALLNSAGL GAADLFVLPA NCGSSDGCEE LERLRAALQS QAEALRRLLP
PAQDGFEVLG AAELEAVREA FETGGLEAAL SWVRSGLERL GSARLDLAVA GKADVGLVVD
MLLGLDPGDP GAAPASVPTA PTPFPAPERP NVVLWTVPLG HTGTATTAAA ASHPTHYDAL
ILVTPGAPTE KDWAQVQALL LPDAPLVCVR TDGEGEDPEC LGEGKMENPK GESLKNAGGG
GLENALSKGR EKCSAGSQKA GSGEGPGKAG SEGLQQVVGM KKSGGGDSER AAALSPEDET
WEVLEEAPPP VFPLRPGGLP GLCEWLRRAL PPAQAGALLL ALPPASPSAA RTKAAALRAG
AWRPALLASL AAAAAPLPGL GWACDVALLR GQLAEWRRGL GLEPTALARR ERALGLASGE
LAARAHFPGP VTRAEVEARL GAWAGEGTAG GAALGALSFL WPAGGAAATG GLGYRAAHGV
LLQALDEMRA DAEAVLAPPE PAQ
//