Full text data of IGKV1-5
IGKV1-5
[Confidence: low (only semi-automatic identification from reviews)]
Ig kappa chain V-I region HK102; Flags: Precursor; Fragment
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Ig kappa chain V-I region HK102; Flags: Precursor; Fragment
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
P01602
ID KV110_HUMAN Reviewed; 117 AA.
AC P01602;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
read moreDT 21-JUL-1986, sequence version 1.
DT 22-JAN-2014, entry version 102.
DE RecName: Full=Ig kappa chain V-I region HK102;
DE Flags: Precursor; Fragment;
GN Name=IGKV1-5;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=6779204; DOI=10.1038/288730a0;
RA Bentley D.L., Rabbitts T.H.;
RT "Human immunoglobulin variable region genes -- DNA sequences of two V
RT kappa genes and a pseudogene.";
RL Nature 288:730-733(1980).
CC -!- WEB RESOURCE: Name=IMGT/GENE-DB;
CC URL="http://www.imgt.org/IMGT_GENE-DB/GENElect?query=2+IGKV1-5&species;=Homo+sapiens";
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CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
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DR EMBL; J00245; AAA59087.1; -; Genomic_DNA.
DR EMBL; Z00001; CAA77292.1; -; Genomic_DNA.
DR PIR; A01882; K1HU12.
DR UniGene; Hs.449609; -.
DR ProteinModelPortal; P01602; -.
DR SMR; P01602; 23-117.
DR IntAct; P01602; 3.
DR STRING; 9606.ENSP00000420436; -.
DR DMDM; 125766; -.
DR PaxDb; P01602; -.
DR PRIDE; P01602; -.
DR GeneCards; GC02M089246; -.
DR HGNC; HGNC:5741; IGKV1-5.
DR eggNOG; NOG327611; -.
DR HOGENOM; HOG000059537; -.
DR HOVERGEN; HBG018013; -.
DR InParanoid; P01602; -.
DR Reactome; REACT_160300; Binding and Uptake of Ligands by Scavenger Receptors.
DR Reactome; REACT_6900; Immune System.
DR Genevestigator; P01602; -.
DR GO; GO:0005576; C:extracellular region; NAS:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; TAS:Reactome.
DR GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR003596; Ig_V-set_subgr.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00406; IGv; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Complete proteome; Disulfide bond; Immunoglobulin domain;
KW Immunoglobulin V region; Reference proteome; Signal.
FT SIGNAL 1 22
FT CHAIN 23 >117 Ig kappa chain V-I region HK102.
FT /FTId=PRO_0000015169.
FT REGION 23 45 Framework-1.
FT REGION 46 56 Complementarity-determining-1.
FT REGION 57 71 Framework-2.
FT REGION 72 78 Complementarity-determining-2.
FT REGION 79 110 Framework-3.
FT REGION 111 >117 Complementarity-determining-3.
FT DISULFID 45 110 By similarity.
FT NON_TER 117 117
SQ SEQUENCE 117 AA; 12768 MW; AD1DF3A40AF1A49B CRC64;
MDMRVPAQLL GLLLLWLPGA KCDIQMTQSP STLSASVGDR VTITCRASQS ISSWLAWYQQ
KPGKAPKLLI YDASSLESGV PSRFSGSGSG TEFTLTISSL QPDDFATYYC QQYNSYS
//
ID KV110_HUMAN Reviewed; 117 AA.
AC P01602;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
read moreDT 21-JUL-1986, sequence version 1.
DT 22-JAN-2014, entry version 102.
DE RecName: Full=Ig kappa chain V-I region HK102;
DE Flags: Precursor; Fragment;
GN Name=IGKV1-5;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=6779204; DOI=10.1038/288730a0;
RA Bentley D.L., Rabbitts T.H.;
RT "Human immunoglobulin variable region genes -- DNA sequences of two V
RT kappa genes and a pseudogene.";
RL Nature 288:730-733(1980).
CC -!- WEB RESOURCE: Name=IMGT/GENE-DB;
CC URL="http://www.imgt.org/IMGT_GENE-DB/GENElect?query=2+IGKV1-5&species;=Homo+sapiens";
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; J00245; AAA59087.1; -; Genomic_DNA.
DR EMBL; Z00001; CAA77292.1; -; Genomic_DNA.
DR PIR; A01882; K1HU12.
DR UniGene; Hs.449609; -.
DR ProteinModelPortal; P01602; -.
DR SMR; P01602; 23-117.
DR IntAct; P01602; 3.
DR STRING; 9606.ENSP00000420436; -.
DR DMDM; 125766; -.
DR PaxDb; P01602; -.
DR PRIDE; P01602; -.
DR GeneCards; GC02M089246; -.
DR HGNC; HGNC:5741; IGKV1-5.
DR eggNOG; NOG327611; -.
DR HOGENOM; HOG000059537; -.
DR HOVERGEN; HBG018013; -.
DR InParanoid; P01602; -.
DR Reactome; REACT_160300; Binding and Uptake of Ligands by Scavenger Receptors.
DR Reactome; REACT_6900; Immune System.
DR Genevestigator; P01602; -.
DR GO; GO:0005576; C:extracellular region; NAS:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; TAS:Reactome.
DR GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR003596; Ig_V-set_subgr.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00406; IGv; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Complete proteome; Disulfide bond; Immunoglobulin domain;
KW Immunoglobulin V region; Reference proteome; Signal.
FT SIGNAL 1 22
FT CHAIN 23 >117 Ig kappa chain V-I region HK102.
FT /FTId=PRO_0000015169.
FT REGION 23 45 Framework-1.
FT REGION 46 56 Complementarity-determining-1.
FT REGION 57 71 Framework-2.
FT REGION 72 78 Complementarity-determining-2.
FT REGION 79 110 Framework-3.
FT REGION 111 >117 Complementarity-determining-3.
FT DISULFID 45 110 By similarity.
FT NON_TER 117 117
SQ SEQUENCE 117 AA; 12768 MW; AD1DF3A40AF1A49B CRC64;
MDMRVPAQLL GLLLLWLPGA KCDIQMTQSP STLSASVGDR VTITCRASQS ISSWLAWYQQ
KPGKAPKLLI YDASSLESGV PSRFSGSGSG TEFTLTISSL QPDDFATYYC QQYNSYS
//