Full text data of METTL7A
METTL7A
[Confidence: medium (present in either hRBCD or BSc_CH or PM22954596)]
Methyltransferase-like protein 7A; 2.1.1.- (Protein AAM-B; Flags: Precursor)
Methyltransferase-like protein 7A; 2.1.1.- (Protein AAM-B; Flags: Precursor)
hRBCD
IPI00022300
IPI00022300 Hypothetical protein FLJ14347 Hypothetical protein FLJ14347 membrane n/a 1 2 2 2 n/a 2 n/a 2 n/a n/a 1 1 n/a n/a n/a 2 2 1 1 not mentioned n/a found at its expected molecular weight found at molecular weight
IPI00022300 Hypothetical protein FLJ14347 Hypothetical protein FLJ14347 membrane n/a 1 2 2 2 n/a 2 n/a 2 n/a n/a 1 1 n/a n/a n/a 2 2 1 1 not mentioned n/a found at its expected molecular weight found at molecular weight
UniProt
Q9H8H3
ID MET7A_HUMAN Reviewed; 244 AA.
AC Q9H8H3; Q9H7R3; Q9UHZ7; Q9Y422;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAR-2001, sequence version 1.
DT 22-JAN-2014, entry version 101.
DE RecName: Full=Methyltransferase-like protein 7A;
DE EC=2.1.1.-;
DE AltName: Full=Protein AAM-B;
DE Flags: Precursor;
GN Name=METTL7A; ORFNames=PRO0066, UNQ1902/PRO4348;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Gratchev A., Kzhyhskowska J., Utikal J., Goerdt S.;
RT "Expression profiling of alternatively activated macrophages.";
RL Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=12975309; DOI=10.1101/gr.1293003;
RA Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J.,
RA Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P.,
RA Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S.,
RA Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J.,
RA Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J.,
RA Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A.,
RA Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H.,
RA Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D.,
RA Wood W.I., Godowski P.J., Gray A.M.;
RT "The secreted protein discovery initiative (SPDI), a large-scale
RT effort to identify novel human secreted and transmembrane proteins: a
RT bioinformatics assessment.";
RL Genome Res. 13:2265-2270(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Placenta, and Thyroid;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Pancreas, and Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-244.
RC TISSUE=Uterus;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,
RA Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,
RA Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 14-244.
RC TISSUE=Fetal liver;
RA Zhang C., Yu Y., Zhang S., Ouyang S., Luo L., Wei H., Zhou G., Liu M.,
RA He F.;
RT "Functional prediction of the coding sequences of 14 new genes deduced
RT by analysis of cDNA clones from human fetal liver.";
RL Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP SUBCELLULAR LOCATION, SUBUNIT, AND REGION.
RX PubMed=18477614; DOI=10.1242/jcs.012013;
RA Zehmer J.K., Bartz R., Liu P., Anderson R.G.W.;
RT "Identification of a novel N-terminal hydrophobic sequence that
RT targets proteins to lipid droplets.";
RL J. Cell Sci. 121:1852-1860(2008).
RN [8]
RP SUBCELLULAR LOCATION.
RX PubMed=19773358; DOI=10.1242/jcs.054700;
RA Zehmer J.K., Bartz R., Bisel B., Liu P., Seemann J., Anderson R.G.W.;
RT "Targeting sequences of UBXD8 and AAM-B reveal that the ER has a
RT direct role in the emergence and regression of lipid droplets.";
RL J. Cell Sci. 122:3694-3702(2009).
RN [9]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- FUNCTION: Probable methyltransferase (By similarity).
CC -!- SUBUNIT: Self-associates.
CC -!- SUBCELLULAR LOCATION: Lipid droplet. Endoplasmic reticulum.
CC Membrane.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF20268.1; Type=Erroneous initiation;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AJ536233; CAD60207.1; -; mRNA.
DR EMBL; AY358797; AAQ89157.1; -; mRNA.
DR EMBL; AK023693; BAB14643.1; -; mRNA.
DR EMBL; AK024409; BAB14913.1; -; mRNA.
DR EMBL; BC004492; AAH04492.1; -; mRNA.
DR EMBL; BC008180; AAH08180.1; -; mRNA.
DR EMBL; AL050159; CAB43300.1; -; mRNA.
DR EMBL; AF113007; AAF20268.1; ALT_INIT; mRNA.
DR PIR; T08785; T08785.
DR RefSeq; NP_054752.3; NM_014033.3.
DR RefSeq; XP_005268839.1; XM_005268782.1.
DR UniGene; Hs.711113; -.
DR UniGene; Hs.744021; -.
DR ProteinModelPortal; Q9H8H3; -.
DR IntAct; Q9H8H3; 1.
DR PhosphoSite; Q9H8H3; -.
DR DMDM; 74761529; -.
DR PaxDb; Q9H8H3; -.
DR PeptideAtlas; Q9H8H3; -.
DR PRIDE; Q9H8H3; -.
DR DNASU; 25840; -.
DR Ensembl; ENST00000332160; ENSP00000331787; ENSG00000185432.
DR Ensembl; ENST00000546513; ENSP00000447184; ENSG00000185432.
DR Ensembl; ENST00000547104; ENSP00000447542; ENSG00000185432.
DR Ensembl; ENST00000548553; ENSP00000448785; ENSG00000185432.
DR GeneID; 25840; -.
DR KEGG; hsa:25840; -.
DR UCSC; uc001rxb.3; human.
DR CTD; 25840; -.
DR GeneCards; GC12P051318; -.
DR HGNC; HGNC:24550; METTL7A.
DR HPA; HPA017434; -.
DR neXtProt; NX_Q9H8H3; -.
DR PharmGKB; PA128394635; -.
DR eggNOG; COG0500; -.
DR HOGENOM; HOG000236770; -.
DR HOVERGEN; HBG054283; -.
DR InParanoid; Q9H8H3; -.
DR OMA; WYYFGDG; -.
DR OrthoDB; EOG73RBCN; -.
DR PhylomeDB; Q9H8H3; -.
DR ChiTaRS; METTL7A; human.
DR GenomeRNAi; 25840; -.
DR NextBio; 47155; -.
DR PRO; PR:Q9H8H3; -.
DR ArrayExpress; Q9H8H3; -.
DR Bgee; Q9H8H3; -.
DR CleanEx; HS_METTL7A; -.
DR Genevestigator; Q9H8H3; -.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR InterPro; IPR013216; Methyltransf_11.
DR Pfam; PF08241; Methyltransf_11; 1.
PE 1: Evidence at protein level;
KW Complete proteome; Endoplasmic reticulum; Lipid droplet; Membrane;
KW Methyltransferase; Polymorphism; Reference proteome; Signal;
KW Transferase.
FT SIGNAL 1 29 Potential.
FT CHAIN 30 244 Methyltransferase-like protein 7A.
FT /FTId=PRO_0000251921.
FT REGION 1 28 Targeting to lipid droplets.
FT VARIANT 134 134 A -> T (in dbSNP:rs28372674).
FT /FTId=VAR_050296.
FT CONFLICT 39 39 F -> L (in Ref. 3; BAB14913).
SQ SEQUENCE 244 AA; 28319 MW; 6967783BAB2348BE CRC64;
MELTIFILRL AIYILTFPLY LLNFLGLWSW ICKKWFPYFL VRFTVIYNEQ MASKKRELFS
NLQEFAGPSG KLSLLEVGCG TGANFKFYPP GCRVTCIDPN PNFEKFLIKS IAENRHLQFE
RFVVAAGENM HQVADGSVDV VVCTLVLCSV KNQERILREV CRVLRPGGAF YFMEHVAAEC
STWNYFWQQV LDPAWHLLFD GCNLTRESWK ALERASFSKL KLQHIQAPLS WELVRPHIYG
YAVK
//
ID MET7A_HUMAN Reviewed; 244 AA.
AC Q9H8H3; Q9H7R3; Q9UHZ7; Q9Y422;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAR-2001, sequence version 1.
DT 22-JAN-2014, entry version 101.
DE RecName: Full=Methyltransferase-like protein 7A;
DE EC=2.1.1.-;
DE AltName: Full=Protein AAM-B;
DE Flags: Precursor;
GN Name=METTL7A; ORFNames=PRO0066, UNQ1902/PRO4348;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Gratchev A., Kzhyhskowska J., Utikal J., Goerdt S.;
RT "Expression profiling of alternatively activated macrophages.";
RL Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=12975309; DOI=10.1101/gr.1293003;
RA Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J.,
RA Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P.,
RA Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S.,
RA Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J.,
RA Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J.,
RA Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A.,
RA Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H.,
RA Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D.,
RA Wood W.I., Godowski P.J., Gray A.M.;
RT "The secreted protein discovery initiative (SPDI), a large-scale
RT effort to identify novel human secreted and transmembrane proteins: a
RT bioinformatics assessment.";
RL Genome Res. 13:2265-2270(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Placenta, and Thyroid;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Pancreas, and Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-244.
RC TISSUE=Uterus;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,
RA Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,
RA Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 14-244.
RC TISSUE=Fetal liver;
RA Zhang C., Yu Y., Zhang S., Ouyang S., Luo L., Wei H., Zhou G., Liu M.,
RA He F.;
RT "Functional prediction of the coding sequences of 14 new genes deduced
RT by analysis of cDNA clones from human fetal liver.";
RL Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP SUBCELLULAR LOCATION, SUBUNIT, AND REGION.
RX PubMed=18477614; DOI=10.1242/jcs.012013;
RA Zehmer J.K., Bartz R., Liu P., Anderson R.G.W.;
RT "Identification of a novel N-terminal hydrophobic sequence that
RT targets proteins to lipid droplets.";
RL J. Cell Sci. 121:1852-1860(2008).
RN [8]
RP SUBCELLULAR LOCATION.
RX PubMed=19773358; DOI=10.1242/jcs.054700;
RA Zehmer J.K., Bartz R., Bisel B., Liu P., Seemann J., Anderson R.G.W.;
RT "Targeting sequences of UBXD8 and AAM-B reveal that the ER has a
RT direct role in the emergence and regression of lipid droplets.";
RL J. Cell Sci. 122:3694-3702(2009).
RN [9]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- FUNCTION: Probable methyltransferase (By similarity).
CC -!- SUBUNIT: Self-associates.
CC -!- SUBCELLULAR LOCATION: Lipid droplet. Endoplasmic reticulum.
CC Membrane.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF20268.1; Type=Erroneous initiation;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AJ536233; CAD60207.1; -; mRNA.
DR EMBL; AY358797; AAQ89157.1; -; mRNA.
DR EMBL; AK023693; BAB14643.1; -; mRNA.
DR EMBL; AK024409; BAB14913.1; -; mRNA.
DR EMBL; BC004492; AAH04492.1; -; mRNA.
DR EMBL; BC008180; AAH08180.1; -; mRNA.
DR EMBL; AL050159; CAB43300.1; -; mRNA.
DR EMBL; AF113007; AAF20268.1; ALT_INIT; mRNA.
DR PIR; T08785; T08785.
DR RefSeq; NP_054752.3; NM_014033.3.
DR RefSeq; XP_005268839.1; XM_005268782.1.
DR UniGene; Hs.711113; -.
DR UniGene; Hs.744021; -.
DR ProteinModelPortal; Q9H8H3; -.
DR IntAct; Q9H8H3; 1.
DR PhosphoSite; Q9H8H3; -.
DR DMDM; 74761529; -.
DR PaxDb; Q9H8H3; -.
DR PeptideAtlas; Q9H8H3; -.
DR PRIDE; Q9H8H3; -.
DR DNASU; 25840; -.
DR Ensembl; ENST00000332160; ENSP00000331787; ENSG00000185432.
DR Ensembl; ENST00000546513; ENSP00000447184; ENSG00000185432.
DR Ensembl; ENST00000547104; ENSP00000447542; ENSG00000185432.
DR Ensembl; ENST00000548553; ENSP00000448785; ENSG00000185432.
DR GeneID; 25840; -.
DR KEGG; hsa:25840; -.
DR UCSC; uc001rxb.3; human.
DR CTD; 25840; -.
DR GeneCards; GC12P051318; -.
DR HGNC; HGNC:24550; METTL7A.
DR HPA; HPA017434; -.
DR neXtProt; NX_Q9H8H3; -.
DR PharmGKB; PA128394635; -.
DR eggNOG; COG0500; -.
DR HOGENOM; HOG000236770; -.
DR HOVERGEN; HBG054283; -.
DR InParanoid; Q9H8H3; -.
DR OMA; WYYFGDG; -.
DR OrthoDB; EOG73RBCN; -.
DR PhylomeDB; Q9H8H3; -.
DR ChiTaRS; METTL7A; human.
DR GenomeRNAi; 25840; -.
DR NextBio; 47155; -.
DR PRO; PR:Q9H8H3; -.
DR ArrayExpress; Q9H8H3; -.
DR Bgee; Q9H8H3; -.
DR CleanEx; HS_METTL7A; -.
DR Genevestigator; Q9H8H3; -.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR InterPro; IPR013216; Methyltransf_11.
DR Pfam; PF08241; Methyltransf_11; 1.
PE 1: Evidence at protein level;
KW Complete proteome; Endoplasmic reticulum; Lipid droplet; Membrane;
KW Methyltransferase; Polymorphism; Reference proteome; Signal;
KW Transferase.
FT SIGNAL 1 29 Potential.
FT CHAIN 30 244 Methyltransferase-like protein 7A.
FT /FTId=PRO_0000251921.
FT REGION 1 28 Targeting to lipid droplets.
FT VARIANT 134 134 A -> T (in dbSNP:rs28372674).
FT /FTId=VAR_050296.
FT CONFLICT 39 39 F -> L (in Ref. 3; BAB14913).
SQ SEQUENCE 244 AA; 28319 MW; 6967783BAB2348BE CRC64;
MELTIFILRL AIYILTFPLY LLNFLGLWSW ICKKWFPYFL VRFTVIYNEQ MASKKRELFS
NLQEFAGPSG KLSLLEVGCG TGANFKFYPP GCRVTCIDPN PNFEKFLIKS IAENRHLQFE
RFVVAAGENM HQVADGSVDV VVCTLVLCSV KNQERILREV CRVLRPGGAF YFMEHVAAEC
STWNYFWQQV LDPAWHLLFD GCNLTRESWK ALERASFSKL KLQHIQAPLS WELVRPHIYG
YAVK
//