Full text data of ZZZZ
P04220
[Confidence: low (only semi-automatic identification from reviews)]
Ig mu heavy chain disease protein (BOT)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Ig mu heavy chain disease protein (BOT)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
P04220
ID MUCB_HUMAN Reviewed; 391 AA.
AC P04220;
DT 20-MAR-1987, integrated into UniProtKB/Swiss-Prot.
read moreDT 20-MAR-1987, sequence version 1.
DT 22-JAN-2014, entry version 80.
DE RecName: Full=Ig mu heavy chain disease protein;
DE AltName: Full=BOT;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=6425189;
RA Barnikol-Watanabe S., Mihaesco E., Mihaesco C., Barnikol H.U.,
RA Hilschmann N.;
RT "The primary structure of mu-chain-disease protein BOT. Peculiar
RT amino-acid sequence of the N-terminal 42 positions.";
RL Hoppe-Seyler's Z. Physiol. Chem. 365:105-118(1984).
RN [2]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-217, AND MASS
RP SPECTROMETRY.
RC TISSUE=Liver;
RX PubMed=19159218; DOI=10.1021/pr8008012;
RA Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.;
RT "Glycoproteomics analysis of human liver tissue by combination of
RT multiple enzyme digestion and hydrazide chemistry.";
RL J. Proteome Res. 8:651-661(2009).
CC -!- MISCELLANEOUS: This protein has no V region homology or CH1
CC region.
CC -----------------------------------------------------------------------
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DR PIR; A02163; MHHUBT.
DR ProteinModelPortal; P04220; -.
DR SMR; P04220; 14-371.
DR DMDM; 127506; -.
DR PaxDb; P04220; -.
DR PeptideAtlas; P04220; -.
DR PRIDE; P04220; -.
DR eggNOG; NOG47782; -.
DR HOVERGEN; HBG005814; -.
DR NextBio; 35537726; -.
DR Genevestigator; P04220; -.
DR GO; GO:0016020; C:membrane; NAS:UniProtKB.
DR GO; GO:0003823; F:antigen binding; TAS:UniProtKB.
DR GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR Gene3D; 2.60.40.10; -; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR Pfam; PF07654; C1-set; 3.
DR SMART; SM00407; IGc1; 2.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS00290; IG_MHC; 3.
PE 1: Evidence at protein level;
KW Complete proteome; Direct protein sequencing; Glycoprotein;
KW Immunoglobulin C region; Immunoglobulin domain; Reference proteome.
FT CHAIN 1 391 Ig mu heavy chain disease protein.
FT /FTId=PRO_0000153621.
FT REGION 1 42 Pre-C-part (no V region homology).
FT REGION 43 155 CH2.
FT REGION 156 261 CH3.
FT REGION 262 391 CH4.
FT CARBOHYD 217 217 N-linked (GlcNAc...).
SQ SEQUENCE 391 AA; 43057 MW; 9100843AF0CF021A CRC64;
DSPLEQSGHE VGILKETEAE DRIIKEEEAR LSGRDMQVTS QPVIAELPPK VSVFVPPRDG
FFGNPRKSKL ICQATGFSPR QIEVSWLREG KQVGSGVTTD EVEAEAKESG PTTYKVTSTL
TIKESDWLGQ SMFTCRVDHR GLTFQQNASS MCGPDQDTAI RVFAIPPSFA SIFLTKSTKL
TCLVTDLTTY DSVTISWTRQ DGEAVKTHTN ISESHPNATF SAVGEASICE DDWDSGERFT
CTVTHTDLPS PLKQTISRPK GVALHRPDVY LLPPAREQLN LRESATITCL VTGFSPADVF
VQWMQRGQPL SPEKYVTSAP MPEPQAPGRY FAHSILTVSE EEWNTGETYT CVVAHEALPN
RVTERTVDKS TGKPTLYNVS LVMSDTAGTC Y
//
ID MUCB_HUMAN Reviewed; 391 AA.
AC P04220;
DT 20-MAR-1987, integrated into UniProtKB/Swiss-Prot.
read moreDT 20-MAR-1987, sequence version 1.
DT 22-JAN-2014, entry version 80.
DE RecName: Full=Ig mu heavy chain disease protein;
DE AltName: Full=BOT;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=6425189;
RA Barnikol-Watanabe S., Mihaesco E., Mihaesco C., Barnikol H.U.,
RA Hilschmann N.;
RT "The primary structure of mu-chain-disease protein BOT. Peculiar
RT amino-acid sequence of the N-terminal 42 positions.";
RL Hoppe-Seyler's Z. Physiol. Chem. 365:105-118(1984).
RN [2]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-217, AND MASS
RP SPECTROMETRY.
RC TISSUE=Liver;
RX PubMed=19159218; DOI=10.1021/pr8008012;
RA Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.;
RT "Glycoproteomics analysis of human liver tissue by combination of
RT multiple enzyme digestion and hydrazide chemistry.";
RL J. Proteome Res. 8:651-661(2009).
CC -!- MISCELLANEOUS: This protein has no V region homology or CH1
CC region.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR PIR; A02163; MHHUBT.
DR ProteinModelPortal; P04220; -.
DR SMR; P04220; 14-371.
DR DMDM; 127506; -.
DR PaxDb; P04220; -.
DR PeptideAtlas; P04220; -.
DR PRIDE; P04220; -.
DR eggNOG; NOG47782; -.
DR HOVERGEN; HBG005814; -.
DR NextBio; 35537726; -.
DR Genevestigator; P04220; -.
DR GO; GO:0016020; C:membrane; NAS:UniProtKB.
DR GO; GO:0003823; F:antigen binding; TAS:UniProtKB.
DR GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR Gene3D; 2.60.40.10; -; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR Pfam; PF07654; C1-set; 3.
DR SMART; SM00407; IGc1; 2.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS00290; IG_MHC; 3.
PE 1: Evidence at protein level;
KW Complete proteome; Direct protein sequencing; Glycoprotein;
KW Immunoglobulin C region; Immunoglobulin domain; Reference proteome.
FT CHAIN 1 391 Ig mu heavy chain disease protein.
FT /FTId=PRO_0000153621.
FT REGION 1 42 Pre-C-part (no V region homology).
FT REGION 43 155 CH2.
FT REGION 156 261 CH3.
FT REGION 262 391 CH4.
FT CARBOHYD 217 217 N-linked (GlcNAc...).
SQ SEQUENCE 391 AA; 43057 MW; 9100843AF0CF021A CRC64;
DSPLEQSGHE VGILKETEAE DRIIKEEEAR LSGRDMQVTS QPVIAELPPK VSVFVPPRDG
FFGNPRKSKL ICQATGFSPR QIEVSWLREG KQVGSGVTTD EVEAEAKESG PTTYKVTSTL
TIKESDWLGQ SMFTCRVDHR GLTFQQNASS MCGPDQDTAI RVFAIPPSFA SIFLTKSTKL
TCLVTDLTTY DSVTISWTRQ DGEAVKTHTN ISESHPNATF SAVGEASICE DDWDSGERFT
CTVTHTDLPS PLKQTISRPK GVALHRPDVY LLPPAREQLN LRESATITCL VTGFSPADVF
VQWMQRGQPL SPEKYVTSAP MPEPQAPGRY FAHSILTVSE EEWNTGETYT CVVAHEALPN
RVTERTVDKS TGKPTLYNVS LVMSDTAGTC Y
//