RBCC

Full text data of OR10A6

OR10A6 [Confidence: low (only semi-automatic identification from reviews)]
Olfactory receptor 10A6 (Olfactory receptor OR11-96)

UniProt Q8NH74
ID O10A6_HUMAN Reviewed; 314 AA.
AC Q8NH74; Q6IF59;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-OCT-2002, sequence version 1.
DT 22-JAN-2014, entry version 97.
DE RecName: Full=Olfactory receptor 10A6;
DE AltName: Full=Olfactory receptor OR11-96;
GN Name=OR10A6;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,
RA Tsutsumi S., Aburatani H., Asai K., Akiyama Y.;
RT "Genome-wide discovery and analysis of human seven transmembrane helix
RT receptor genes.";
RL Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP IDENTIFICATION.
RX PubMed=14983052; DOI=10.1073/pnas.0307882100;
RA Malnic B., Godfrey P.A., Buck L.B.;
RT "The human olfactory receptor gene family.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:2584-2589(2004).
RN [3]
RP ERRATUM.
RA Malnic B., Godfrey P.A., Buck L.B.;
RL Proc. Natl. Acad. Sci. U.S.A. 101:7205-7205(2004).
CC -!- FUNCTION: Odorant receptor (Potential).
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC -!- WEB RESOURCE: Name=Human Olfactory Receptor Data Exploratorium
CC (HORDE);
CC URL="http://bip.weizmann.ac.il/cgi-bin/HORDE/showGene.pl?key=symbol&value;=OR10A6";
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AB065515; BAC05763.1; -; Genomic_DNA.
DR EMBL; BK004403; DAA04801.1; -; Genomic_DNA.
DR RefSeq; NP_001004461.1; NM_001004461.1.
DR UniGene; Hs.528593; -.
DR ProteinModelPortal; Q8NH74; -.
DR SMR; Q8NH74; 32-310.
DR STRING; 9606.ENSP00000312470; -.
DR PhosphoSite; Q8NH74; -.
DR DMDM; 38372823; -.
DR PaxDb; Q8NH74; -.
DR PRIDE; Q8NH74; -.
DR Ensembl; ENST00000309838; ENSP00000312470; ENSG00000175393.
DR GeneID; 390093; -.
DR KEGG; hsa:390093; -.
DR UCSC; uc010rbh.2; human.
DR CTD; 390093; -.
DR GeneCards; GC11M007949; -.
DR HGNC; HGNC:15132; OR10A6.
DR neXtProt; NX_Q8NH74; -.
DR PharmGKB; PA31954; -.
DR eggNOG; NOG150795; -.
DR HOGENOM; HOG000041365; -.
DR HOVERGEN; HBG017625; -.
DR InParanoid; Q8NH74; -.
DR KO; K04257; -.
DR OMA; GTVQTSW; -.
DR OrthoDB; EOG7SXW3S; -.
DR PhylomeDB; Q8NH74; -.
DR Reactome; REACT_111102; Signal Transduction.
DR GeneWiki; OR10A6; -.
DR GenomeRNAi; 390093; -.
DR NextBio; 103390; -.
DR PRO; PR:Q8NH74; -.
DR Bgee; Q8NH74; -.
DR CleanEx; HS_OR10A6; -.
DR Genevestigator; Q8NH74; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; TAS:Reactome.
DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; IEA:GOC.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Complete proteome; Disulfide bond;
KW G-protein coupled receptor; Glycoprotein; Membrane; Olfaction;
KW Polymorphism; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1 314 Olfactory receptor 10A6.
FT /FTId=PRO_0000150689.
FT TOPO_DOM 1 25 Extracellular (Potential).
FT TRANSMEM 26 46 Helical; Name=1; (Potential).
FT TOPO_DOM 47 54 Cytoplasmic (Potential).
FT TRANSMEM 55 75 Helical; Name=2; (Potential).
FT TOPO_DOM 76 99 Extracellular (Potential).
FT TRANSMEM 100 120 Helical; Name=3; (Potential).
FT TOPO_DOM 121 139 Cytoplasmic (Potential).
FT TRANSMEM 140 160 Helical; Name=4; (Potential).
FT TOPO_DOM 161 197 Extracellular (Potential).
FT TRANSMEM 198 217 Helical; Name=5; (Potential).
FT TOPO_DOM 218 237 Cytoplasmic (Potential).
FT TRANSMEM 238 258 Helical; Name=6; (Potential).
FT TOPO_DOM 259 271 Extracellular (Potential).
FT TRANSMEM 272 292 Helical; Name=7; (Potential).
FT TOPO_DOM 293 314 Cytoplasmic (Potential).
FT CARBOHYD 5 5 N-linked (GlcNAc...) (Potential).
FT DISULFID 97 189 By similarity.
FT VARIANT 117 117 A -> V (in dbSNP:rs7928451).
FT /FTId=VAR_053263.
FT VARIANT 140 140 V -> G (in dbSNP:rs7933807).
FT /FTId=VAR_053264.
FT VARIANT 287 287 L -> P (in dbSNP:rs4758258).
FT /FTId=VAR_053265.
SQ SEQUENCE 314 AA; 35318 MW; 22453498F86381FB CRC64;
MERQNQSCVV EFILLGFSNY PELQGQLFVA FLVIYLVTLI GNAIIIVIVS LDQSLHVPMY
LFLLNLSVVD LSFSAVIMPE MLVVLSTEKT TISFGGCFAQ MYFILLFGGA ECFLLGAMAY
DRFAAICHPL NYQMIMNKGV FMKLIIFSWA LGFMLGTVQT SWVSSFPFCG LNEINHISCE
TPAVLELACA DTFLFEIYAF TGTFLIILVP FLLILLSYIR VLFAILKMPS TTGRQKAFST
CAAHLTSVTL FYGTASMTYL QPKSGYSPET KKVMSLSYSL LTPLLNLLIY SLRNSEMKRA
LMKLWRRRVV LHTI
//

RBCC Red Blood Cell Collection

Full text data of OR10A6