Full text data of OR1G1
OR1G1
(OR1G2)
[Confidence: low (only semi-automatic identification from reviews)]
Olfactory receptor 1G1 (Olfactory receptor 17-209; OR17-209; Olfactory receptor 1G2; Olfactory receptor OR17-8)
Olfactory receptor 1G1 (Olfactory receptor 17-209; OR17-209; Olfactory receptor 1G2; Olfactory receptor OR17-8)
UniProt
P47890
ID OR1G1_HUMAN Reviewed; 313 AA.
AC P47890; Q4VBM1; Q6IFL9; Q9UM76;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-DEC-2000, sequence version 2.
DT 22-JAN-2014, entry version 116.
DE RecName: Full=Olfactory receptor 1G1;
DE AltName: Full=Olfactory receptor 17-209;
DE Short=OR17-209;
DE AltName: Full=Olfactory receptor 1G2;
DE AltName: Full=Olfactory receptor OR17-8;
GN Name=OR1G1; Synonyms=OR1G2;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10673334; DOI=10.1006/geno.1999.6030;
RA Glusman G., Sosinsky A., Ben-Asher E., Avidan N., Sonkin D., Bahar A.,
RA Rosenthal A., Clifton S., Roe B., Ferraz C., Demaille J.G., Lancet D.;
RT "Sequence, structure, and evolution of a complete human olfactory
RT receptor gene cluster.";
RL Genomics 63:227-245(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Ferraz C., Demaille J.G.;
RT "Sequence of cosmid ICRF105cF06137 of the human chromosome 17p13.3
RT olfactory receptor gene cluster.";
RL Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 68-283.
RX PubMed=8004088; DOI=10.1093/hmg/3.2.229;
RA Ben-Arie N., Lancet D., Taylor C., Khen M., Walker N., Ledbetter D.H.,
RA Carrozzo R., Patel K., Sheer D., Lehrach H., North M.A.;
RT "Olfactory receptor gene cluster on human chromosome 17: possible
RT duplication of an ancestral receptor repertoire.";
RL Hum. Mol. Genet. 3:229-235(1994).
RN [5]
RP IDENTIFICATION.
RX PubMed=14983052; DOI=10.1073/pnas.0307882100;
RA Malnic B., Godfrey P.A., Buck L.B.;
RT "The human olfactory receptor gene family.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:2584-2589(2004).
RN [6]
RP ERRATUM.
RA Malnic B., Godfrey P.A., Buck L.B.;
RL Proc. Natl. Acad. Sci. U.S.A. 101:7205-7205(2004).
CC -!- FUNCTION: Odorant receptor (Potential).
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC -!- SEQUENCE CAUTION:
CC Sequence=DAA04641.1; Type=Erroneous initiation;
CC -!- WEB RESOURCE: Name=Human Olfactory Receptor Data Exploratorium
CC (HORDE);
CC URL="http://bip.weizmann.ac.il/cgi-bin/HORDE/showGene.pl?key=symbol&value;=OR1G1";
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AF087928; AAF37317.1; -; Genomic_DNA.
DR EMBL; U53583; AAC99556.1; -; Genomic_DNA.
DR EMBL; BC069379; AAH69379.1; -; mRNA.
DR EMBL; BC095520; AAH95520.1; -; mRNA.
DR EMBL; U04689; AAA18352.1; -; Genomic_DNA.
DR EMBL; BK004243; DAA04641.1; ALT_INIT; Genomic_DNA.
DR PIR; I38481; I38481.
DR RefSeq; NP_003546.1; NM_003555.1.
DR UniGene; Hs.248183; -.
DR ProteinModelPortal; P47890; -.
DR SMR; P47890; 33-305.
DR STRING; 9606.ENSP00000331545; -.
DR DMDM; 9297118; -.
DR Ensembl; ENST00000328890; ENSP00000331545; ENSG00000183024.
DR GeneID; 8390; -.
DR KEGG; hsa:8390; -.
DR UCSC; uc002fvc.1; human.
DR CTD; 8390; -.
DR GeneCards; GC17M003029; -.
DR HGNC; HGNC:8204; OR1G1.
DR neXtProt; NX_P47890; -.
DR PharmGKB; PA32076; -.
DR eggNOG; NOG148217; -.
DR HOGENOM; HOG000041364; -.
DR HOVERGEN; HBG017625; -.
DR InParanoid; P47890; -.
DR KO; K04257; -.
DR OMA; SASWIMN; -.
DR OrthoDB; EOG71K63J; -.
DR PhylomeDB; P47890; -.
DR Reactome; REACT_111102; Signal Transduction.
DR GeneWiki; OR1G1; -.
DR GenomeRNAi; 8390; -.
DR NextBio; 31406; -.
DR PRO; PR:P47890; -.
DR Bgee; P47890; -.
DR CleanEx; HS_OR1G1; -.
DR Genevestigator; P47890; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; TAS:Reactome.
DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; IEA:GOC.
DR GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; FALSE_NEG.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Complete proteome; Disulfide bond;
KW G-protein coupled receptor; Glycoprotein; Membrane; Olfaction;
KW Polymorphism; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1 313 Olfactory receptor 1G1.
FT /FTId=PRO_0000150434.
FT TOPO_DOM 1 25 Extracellular (Potential).
FT TRANSMEM 26 49 Helical; Name=1; (Potential).
FT TOPO_DOM 50 57 Cytoplasmic (Potential).
FT TRANSMEM 58 79 Helical; Name=2; (Potential).
FT TOPO_DOM 80 100 Extracellular (Potential).
FT TRANSMEM 101 120 Helical; Name=3; (Potential).
FT TOPO_DOM 121 140 Cytoplasmic (Potential).
FT TRANSMEM 141 158 Helical; Name=4; (Potential).
FT TOPO_DOM 159 196 Extracellular (Potential).
FT TRANSMEM 197 219 Helical; Name=5; (Potential).
FT TOPO_DOM 220 236 Cytoplasmic (Potential).
FT TRANSMEM 237 259 Helical; Name=6; (Potential).
FT TOPO_DOM 260 272 Extracellular (Potential).
FT TRANSMEM 273 292 Helical; Name=7; (Potential).
FT TOPO_DOM 293 313 Cytoplasmic (Potential).
FT CARBOHYD 5 5 N-linked (GlcNAc...) (Potential).
FT DISULFID 97 189 By similarity.
FT VARIANT 88 88 Q -> H (in dbSNP:rs9892491).
FT /FTId=VAR_053122.
FT CONFLICT 95 95 S -> L (in Ref. 4; AAA18352).
FT CONFLICT 125 125 A -> G (in Ref. 4; AAA18352).
SQ SEQUENCE 313 AA; 34924 MW; 556C28EB731FD003 CRC64;
MEGKNLTSIS ECFLLGFSEQ LEEQKPLFGS FLFMYLVTVA GNLLIILVII TDTQLHTPMY
FFLANLSLAD ACFVSTTVPK MLANIQIQSQ AISYSGCLLQ LYFFMLFVML EAFLLAVMAY
DCYVAICHPL HYILIMSPGL CIFLVSASWI MNALHSLLHT LLMNSLSFCA NHEIPHFFCD
INPLLSLSCT DPFTNELVIF ITGGLTGLIC VLCLIISYTN VFSTILKIPS AQGKRKAFST
CSSHLSVVSL FFGTSFCVDF SSPSTHSAQK DTVASVMYTV VTPMLNPFIY SLRNQEIKSS
LRKLIWVRKI HSP
//
ID OR1G1_HUMAN Reviewed; 313 AA.
AC P47890; Q4VBM1; Q6IFL9; Q9UM76;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-DEC-2000, sequence version 2.
DT 22-JAN-2014, entry version 116.
DE RecName: Full=Olfactory receptor 1G1;
DE AltName: Full=Olfactory receptor 17-209;
DE Short=OR17-209;
DE AltName: Full=Olfactory receptor 1G2;
DE AltName: Full=Olfactory receptor OR17-8;
GN Name=OR1G1; Synonyms=OR1G2;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10673334; DOI=10.1006/geno.1999.6030;
RA Glusman G., Sosinsky A., Ben-Asher E., Avidan N., Sonkin D., Bahar A.,
RA Rosenthal A., Clifton S., Roe B., Ferraz C., Demaille J.G., Lancet D.;
RT "Sequence, structure, and evolution of a complete human olfactory
RT receptor gene cluster.";
RL Genomics 63:227-245(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Ferraz C., Demaille J.G.;
RT "Sequence of cosmid ICRF105cF06137 of the human chromosome 17p13.3
RT olfactory receptor gene cluster.";
RL Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 68-283.
RX PubMed=8004088; DOI=10.1093/hmg/3.2.229;
RA Ben-Arie N., Lancet D., Taylor C., Khen M., Walker N., Ledbetter D.H.,
RA Carrozzo R., Patel K., Sheer D., Lehrach H., North M.A.;
RT "Olfactory receptor gene cluster on human chromosome 17: possible
RT duplication of an ancestral receptor repertoire.";
RL Hum. Mol. Genet. 3:229-235(1994).
RN [5]
RP IDENTIFICATION.
RX PubMed=14983052; DOI=10.1073/pnas.0307882100;
RA Malnic B., Godfrey P.A., Buck L.B.;
RT "The human olfactory receptor gene family.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:2584-2589(2004).
RN [6]
RP ERRATUM.
RA Malnic B., Godfrey P.A., Buck L.B.;
RL Proc. Natl. Acad. Sci. U.S.A. 101:7205-7205(2004).
CC -!- FUNCTION: Odorant receptor (Potential).
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC -!- SEQUENCE CAUTION:
CC Sequence=DAA04641.1; Type=Erroneous initiation;
CC -!- WEB RESOURCE: Name=Human Olfactory Receptor Data Exploratorium
CC (HORDE);
CC URL="http://bip.weizmann.ac.il/cgi-bin/HORDE/showGene.pl?key=symbol&value;=OR1G1";
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AF087928; AAF37317.1; -; Genomic_DNA.
DR EMBL; U53583; AAC99556.1; -; Genomic_DNA.
DR EMBL; BC069379; AAH69379.1; -; mRNA.
DR EMBL; BC095520; AAH95520.1; -; mRNA.
DR EMBL; U04689; AAA18352.1; -; Genomic_DNA.
DR EMBL; BK004243; DAA04641.1; ALT_INIT; Genomic_DNA.
DR PIR; I38481; I38481.
DR RefSeq; NP_003546.1; NM_003555.1.
DR UniGene; Hs.248183; -.
DR ProteinModelPortal; P47890; -.
DR SMR; P47890; 33-305.
DR STRING; 9606.ENSP00000331545; -.
DR DMDM; 9297118; -.
DR Ensembl; ENST00000328890; ENSP00000331545; ENSG00000183024.
DR GeneID; 8390; -.
DR KEGG; hsa:8390; -.
DR UCSC; uc002fvc.1; human.
DR CTD; 8390; -.
DR GeneCards; GC17M003029; -.
DR HGNC; HGNC:8204; OR1G1.
DR neXtProt; NX_P47890; -.
DR PharmGKB; PA32076; -.
DR eggNOG; NOG148217; -.
DR HOGENOM; HOG000041364; -.
DR HOVERGEN; HBG017625; -.
DR InParanoid; P47890; -.
DR KO; K04257; -.
DR OMA; SASWIMN; -.
DR OrthoDB; EOG71K63J; -.
DR PhylomeDB; P47890; -.
DR Reactome; REACT_111102; Signal Transduction.
DR GeneWiki; OR1G1; -.
DR GenomeRNAi; 8390; -.
DR NextBio; 31406; -.
DR PRO; PR:P47890; -.
DR Bgee; P47890; -.
DR CleanEx; HS_OR1G1; -.
DR Genevestigator; P47890; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; TAS:Reactome.
DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; IEA:GOC.
DR GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; FALSE_NEG.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Complete proteome; Disulfide bond;
KW G-protein coupled receptor; Glycoprotein; Membrane; Olfaction;
KW Polymorphism; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1 313 Olfactory receptor 1G1.
FT /FTId=PRO_0000150434.
FT TOPO_DOM 1 25 Extracellular (Potential).
FT TRANSMEM 26 49 Helical; Name=1; (Potential).
FT TOPO_DOM 50 57 Cytoplasmic (Potential).
FT TRANSMEM 58 79 Helical; Name=2; (Potential).
FT TOPO_DOM 80 100 Extracellular (Potential).
FT TRANSMEM 101 120 Helical; Name=3; (Potential).
FT TOPO_DOM 121 140 Cytoplasmic (Potential).
FT TRANSMEM 141 158 Helical; Name=4; (Potential).
FT TOPO_DOM 159 196 Extracellular (Potential).
FT TRANSMEM 197 219 Helical; Name=5; (Potential).
FT TOPO_DOM 220 236 Cytoplasmic (Potential).
FT TRANSMEM 237 259 Helical; Name=6; (Potential).
FT TOPO_DOM 260 272 Extracellular (Potential).
FT TRANSMEM 273 292 Helical; Name=7; (Potential).
FT TOPO_DOM 293 313 Cytoplasmic (Potential).
FT CARBOHYD 5 5 N-linked (GlcNAc...) (Potential).
FT DISULFID 97 189 By similarity.
FT VARIANT 88 88 Q -> H (in dbSNP:rs9892491).
FT /FTId=VAR_053122.
FT CONFLICT 95 95 S -> L (in Ref. 4; AAA18352).
FT CONFLICT 125 125 A -> G (in Ref. 4; AAA18352).
SQ SEQUENCE 313 AA; 34924 MW; 556C28EB731FD003 CRC64;
MEGKNLTSIS ECFLLGFSEQ LEEQKPLFGS FLFMYLVTVA GNLLIILVII TDTQLHTPMY
FFLANLSLAD ACFVSTTVPK MLANIQIQSQ AISYSGCLLQ LYFFMLFVML EAFLLAVMAY
DCYVAICHPL HYILIMSPGL CIFLVSASWI MNALHSLLHT LLMNSLSFCA NHEIPHFFCD
INPLLSLSCT DPFTNELVIF ITGGLTGLIC VLCLIISYTN VFSTILKIPS AQGKRKAFST
CSSHLSVVSL FFGTSFCVDF SSPSTHSAQK DTVASVMYTV VTPMLNPFIY SLRNQEIKSS
LRKLIWVRKI HSP
//