Full text data of PRRC1
PRRC1
[Confidence: low (only semi-automatic identification from reviews)]
Protein PRRC1 (Proline-rich and coiled-coil-containing protein 1)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Protein PRRC1 (Proline-rich and coiled-coil-containing protein 1)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q96M27
ID PRRC1_HUMAN Reviewed; 445 AA.
AC Q96M27; Q69YM8; Q7L2U7; Q86Y42; Q8IVJ4; Q8IVL4; Q8NEZ7; Q96AJ3;
read moreDT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 22-JAN-2014, entry version 82.
DE RecName: Full=Protein PRRC1;
DE AltName: Full=Proline-rich and coiled-coil-containing protein 1;
GN Name=PRRC1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4), SUBCELLULAR
RP LOCATION, AND TISSUE SPECIFICITY.
RC TISSUE=Heart, Liver, and Peripheral blood;
RX PubMed=15541471; DOI=10.1016/j.leukres.2004.04.019;
RA Kamakari S., Roussou A., Jefferson A., Ragoussis I., Anagnou N.P.;
RT "Structural analysis and expression profile of a novel gene on
RT chromosome 5q23 encoding a Golgi-associated protein with six splice
RT variants, and involved within the 5q deletion of a Ph(-) CML
RT patient.";
RL Leuk. Res. 29:17-31(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Spleen;
RA Jikuya H., Takano J., Kikuno R., Nagase T., Ohara O.;
RT "The nucleotide sequence of a long cDNA clone isolated from human
RT spleen.";
RL Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 5).
RC TISSUE=Skeletal muscle, and Spinal cord;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,
RA Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,
RA Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Uterus;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [7]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-408, AND MASS
RP SPECTROMETRY.
RC TISSUE=Cervix carcinoma;
RX PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA Elledge S.J., Gygi S.P.;
RT "A quantitative atlas of mitotic phosphorylation.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=5;
CC Name=1;
CC IsoId=Q96M27-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q96M27-2; Sequence=VSP_028724;
CC Name=3;
CC IsoId=Q96M27-3; Sequence=VSP_028725;
CC Name=4;
CC IsoId=Q96M27-4; Sequence=VSP_028720, VSP_028721;
CC Name=5;
CC IsoId=Q96M27-5; Sequence=VSP_028722, VSP_028723;
CC Note=No experimental confirmation available;
CC -!- TISSUE SPECIFICITY: Isoform 4 is specifically expressed in liver.
CC Ubiquitously expressed with higher expression in kidney, liver and
CC placenta.
CC -!- SIMILARITY: Belongs to the PRRC1 family.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH17066.1; Type=Erroneous initiation;
CC Sequence=BAC03467.1; Type=Frameshift; Positions=156;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AJ427339; CAD22113.1; -; mRNA.
DR EMBL; AJ441110; CAD29585.2; -; mRNA.
DR EMBL; AJ496322; CAD42881.1; -; mRNA.
DR EMBL; AJ515158; CAD56470.1; -; mRNA.
DR EMBL; AJ515428; CAD56438.1; -; mRNA.
DR EMBL; AJ515429; CAD56439.1; -; mRNA.
DR EMBL; AK090486; BAC03467.1; ALT_FRAME; mRNA.
DR EMBL; AK057437; BAB71487.1; -; mRNA.
DR EMBL; AL831963; CAD38605.1; -; mRNA.
DR EMBL; AL832600; CAH10384.1; ALT_TERM; mRNA.
DR EMBL; CH471062; EAW62402.1; -; Genomic_DNA.
DR EMBL; CH471062; EAW62405.1; -; Genomic_DNA.
DR EMBL; BC017066; AAH17066.1; ALT_INIT; mRNA.
DR RefSeq; NP_570721.1; NM_130809.4.
DR RefSeq; XP_005271935.1; XM_005271878.1.
DR RefSeq; XP_005271936.1; XM_005271879.1.
DR UniGene; Hs.483259; -.
DR ProteinModelPortal; Q96M27; -.
DR IntAct; Q96M27; 2.
DR MINT; MINT-5001825; -.
DR STRING; 9606.ENSP00000296666; -.
DR PhosphoSite; Q96M27; -.
DR DMDM; 74732288; -.
DR PaxDb; Q96M27; -.
DR PRIDE; Q96M27; -.
DR DNASU; 133619; -.
DR Ensembl; ENST00000296666; ENSP00000296666; ENSG00000164244.
DR Ensembl; ENST00000442138; ENSP00000392873; ENSG00000164244.
DR Ensembl; ENST00000512635; ENSP00000421965; ENSG00000164244.
DR GeneID; 133619; -.
DR KEGG; hsa:133619; -.
DR UCSC; uc003kuk.3; human.
DR CTD; 133619; -.
DR GeneCards; GC05P126882; -.
DR H-InvDB; HIX0005138; -.
DR HGNC; HGNC:28164; PRRC1.
DR HPA; HPA039212; -.
DR neXtProt; NX_Q96M27; -.
DR PharmGKB; PA162400175; -.
DR eggNOG; NOG78160; -.
DR HOVERGEN; HBG055574; -.
DR OMA; AIAGMYK; -.
DR OrthoDB; EOG73BVCZ; -.
DR ChiTaRS; PRRC1; human.
DR GenomeRNAi; 133619; -.
DR NextBio; 83254; -.
DR PRO; PR:Q96M27; -.
DR Bgee; Q96M27; -.
DR CleanEx; HS_PRRC1; -.
DR Genevestigator; Q96M27; -.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR InterPro; IPR026533; NTPase/PRRC1.
DR InterPro; IPR026534; PRRC1.
DR PANTHER; PTHR23276; PTHR23276; 1.
DR Pfam; PF01931; NTPase_I-T; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Complete proteome; Golgi apparatus;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1 445 Protein PRRC1.
FT /FTId=PRO_0000307338.
FT COMPBIAS 11 129 Pro-rich.
FT MOD_RES 408 408 Phosphoserine.
FT VAR_SEQ 311 311 E -> A (in isoform 4).
FT /FTId=VSP_028720.
FT VAR_SEQ 312 445 Missing (in isoform 4).
FT /FTId=VSP_028721.
FT VAR_SEQ 377 377 A -> VGFLLCFFIMLQRNLHYCFQNKNLFGFFVRNMFLIL
FT FQSFFF (in isoform 5).
FT /FTId=VSP_028722.
FT VAR_SEQ 378 445 Missing (in isoform 5).
FT /FTId=VSP_028723.
FT VAR_SEQ 433 445 AGMYKQRLPPRTV -> ENPQRAVAVHGLVEARNFPAPGDL
FT VSLLLGTV (in isoform 2).
FT /FTId=VSP_028724.
FT VAR_SEQ 434 445 GMYKQRLPPRTV -> DDYFPRIPKEQWQSMAWLKLEIFLP
FT LVTW (in isoform 3).
FT /FTId=VSP_028725.
FT CONFLICT 70 70 A -> T (in Ref. 4; CAH10384).
FT CONFLICT 338 338 L -> S (in Ref. 4; CAH10384).
SQ SEQUENCE 445 AA; 46701 MW; 68FFE2C1992A2361 CRC64;
MMEESGIETT PPGTPPPNPA GLAATAMSST PVPLAATSSF SSPNVSSMES FPPLAYSTPQ
PPLPPVRPSA PLPFVPPPAV PSVPPLVTSM PPPVSPSTAA AFGNPPVSHF PPSTSAPNTL
LPAPPSGPPI SGFSVGSTYD ITRGHAGRAP QTPLMPSFSA PSGTGLLPTP ITQQASLTSL
AQGTGTTSAI TFPEEQEDPR ITRGQDEASA GGIWGFIKGV AGNPMVKSVL DKTKHSVESM
ITTLDPGMAP YIKSGGELDI VVTSNKEVKV AAVRDAFQEV FGLAVVVGEA GQSNIAPQPV
GYAAGLKGAQ ERIDSLRRTG VIHEKQTAVS VENFIAELLP DKWFDIGCLV VEDPVHGIHL
ETFTQATPVP LEFVQQAQSL TPQDYNLRWS GLLVTVGEVL EKSLLNVSRT DWHMAFTGMS
RRQMIYSAAR AIAGMYKQRL PPRTV
//
ID PRRC1_HUMAN Reviewed; 445 AA.
AC Q96M27; Q69YM8; Q7L2U7; Q86Y42; Q8IVJ4; Q8IVL4; Q8NEZ7; Q96AJ3;
read moreDT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 22-JAN-2014, entry version 82.
DE RecName: Full=Protein PRRC1;
DE AltName: Full=Proline-rich and coiled-coil-containing protein 1;
GN Name=PRRC1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4), SUBCELLULAR
RP LOCATION, AND TISSUE SPECIFICITY.
RC TISSUE=Heart, Liver, and Peripheral blood;
RX PubMed=15541471; DOI=10.1016/j.leukres.2004.04.019;
RA Kamakari S., Roussou A., Jefferson A., Ragoussis I., Anagnou N.P.;
RT "Structural analysis and expression profile of a novel gene on
RT chromosome 5q23 encoding a Golgi-associated protein with six splice
RT variants, and involved within the 5q deletion of a Ph(-) CML
RT patient.";
RL Leuk. Res. 29:17-31(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Spleen;
RA Jikuya H., Takano J., Kikuno R., Nagase T., Ohara O.;
RT "The nucleotide sequence of a long cDNA clone isolated from human
RT spleen.";
RL Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 5).
RC TISSUE=Skeletal muscle, and Spinal cord;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,
RA Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,
RA Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Uterus;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [7]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-408, AND MASS
RP SPECTROMETRY.
RC TISSUE=Cervix carcinoma;
RX PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA Elledge S.J., Gygi S.P.;
RT "A quantitative atlas of mitotic phosphorylation.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=5;
CC Name=1;
CC IsoId=Q96M27-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q96M27-2; Sequence=VSP_028724;
CC Name=3;
CC IsoId=Q96M27-3; Sequence=VSP_028725;
CC Name=4;
CC IsoId=Q96M27-4; Sequence=VSP_028720, VSP_028721;
CC Name=5;
CC IsoId=Q96M27-5; Sequence=VSP_028722, VSP_028723;
CC Note=No experimental confirmation available;
CC -!- TISSUE SPECIFICITY: Isoform 4 is specifically expressed in liver.
CC Ubiquitously expressed with higher expression in kidney, liver and
CC placenta.
CC -!- SIMILARITY: Belongs to the PRRC1 family.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH17066.1; Type=Erroneous initiation;
CC Sequence=BAC03467.1; Type=Frameshift; Positions=156;
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AJ427339; CAD22113.1; -; mRNA.
DR EMBL; AJ441110; CAD29585.2; -; mRNA.
DR EMBL; AJ496322; CAD42881.1; -; mRNA.
DR EMBL; AJ515158; CAD56470.1; -; mRNA.
DR EMBL; AJ515428; CAD56438.1; -; mRNA.
DR EMBL; AJ515429; CAD56439.1; -; mRNA.
DR EMBL; AK090486; BAC03467.1; ALT_FRAME; mRNA.
DR EMBL; AK057437; BAB71487.1; -; mRNA.
DR EMBL; AL831963; CAD38605.1; -; mRNA.
DR EMBL; AL832600; CAH10384.1; ALT_TERM; mRNA.
DR EMBL; CH471062; EAW62402.1; -; Genomic_DNA.
DR EMBL; CH471062; EAW62405.1; -; Genomic_DNA.
DR EMBL; BC017066; AAH17066.1; ALT_INIT; mRNA.
DR RefSeq; NP_570721.1; NM_130809.4.
DR RefSeq; XP_005271935.1; XM_005271878.1.
DR RefSeq; XP_005271936.1; XM_005271879.1.
DR UniGene; Hs.483259; -.
DR ProteinModelPortal; Q96M27; -.
DR IntAct; Q96M27; 2.
DR MINT; MINT-5001825; -.
DR STRING; 9606.ENSP00000296666; -.
DR PhosphoSite; Q96M27; -.
DR DMDM; 74732288; -.
DR PaxDb; Q96M27; -.
DR PRIDE; Q96M27; -.
DR DNASU; 133619; -.
DR Ensembl; ENST00000296666; ENSP00000296666; ENSG00000164244.
DR Ensembl; ENST00000442138; ENSP00000392873; ENSG00000164244.
DR Ensembl; ENST00000512635; ENSP00000421965; ENSG00000164244.
DR GeneID; 133619; -.
DR KEGG; hsa:133619; -.
DR UCSC; uc003kuk.3; human.
DR CTD; 133619; -.
DR GeneCards; GC05P126882; -.
DR H-InvDB; HIX0005138; -.
DR HGNC; HGNC:28164; PRRC1.
DR HPA; HPA039212; -.
DR neXtProt; NX_Q96M27; -.
DR PharmGKB; PA162400175; -.
DR eggNOG; NOG78160; -.
DR HOVERGEN; HBG055574; -.
DR OMA; AIAGMYK; -.
DR OrthoDB; EOG73BVCZ; -.
DR ChiTaRS; PRRC1; human.
DR GenomeRNAi; 133619; -.
DR NextBio; 83254; -.
DR PRO; PR:Q96M27; -.
DR Bgee; Q96M27; -.
DR CleanEx; HS_PRRC1; -.
DR Genevestigator; Q96M27; -.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR InterPro; IPR026533; NTPase/PRRC1.
DR InterPro; IPR026534; PRRC1.
DR PANTHER; PTHR23276; PTHR23276; 1.
DR Pfam; PF01931; NTPase_I-T; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Complete proteome; Golgi apparatus;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1 445 Protein PRRC1.
FT /FTId=PRO_0000307338.
FT COMPBIAS 11 129 Pro-rich.
FT MOD_RES 408 408 Phosphoserine.
FT VAR_SEQ 311 311 E -> A (in isoform 4).
FT /FTId=VSP_028720.
FT VAR_SEQ 312 445 Missing (in isoform 4).
FT /FTId=VSP_028721.
FT VAR_SEQ 377 377 A -> VGFLLCFFIMLQRNLHYCFQNKNLFGFFVRNMFLIL
FT FQSFFF (in isoform 5).
FT /FTId=VSP_028722.
FT VAR_SEQ 378 445 Missing (in isoform 5).
FT /FTId=VSP_028723.
FT VAR_SEQ 433 445 AGMYKQRLPPRTV -> ENPQRAVAVHGLVEARNFPAPGDL
FT VSLLLGTV (in isoform 2).
FT /FTId=VSP_028724.
FT VAR_SEQ 434 445 GMYKQRLPPRTV -> DDYFPRIPKEQWQSMAWLKLEIFLP
FT LVTW (in isoform 3).
FT /FTId=VSP_028725.
FT CONFLICT 70 70 A -> T (in Ref. 4; CAH10384).
FT CONFLICT 338 338 L -> S (in Ref. 4; CAH10384).
SQ SEQUENCE 445 AA; 46701 MW; 68FFE2C1992A2361 CRC64;
MMEESGIETT PPGTPPPNPA GLAATAMSST PVPLAATSSF SSPNVSSMES FPPLAYSTPQ
PPLPPVRPSA PLPFVPPPAV PSVPPLVTSM PPPVSPSTAA AFGNPPVSHF PPSTSAPNTL
LPAPPSGPPI SGFSVGSTYD ITRGHAGRAP QTPLMPSFSA PSGTGLLPTP ITQQASLTSL
AQGTGTTSAI TFPEEQEDPR ITRGQDEASA GGIWGFIKGV AGNPMVKSVL DKTKHSVESM
ITTLDPGMAP YIKSGGELDI VVTSNKEVKV AAVRDAFQEV FGLAVVVGEA GQSNIAPQPV
GYAAGLKGAQ ERIDSLRRTG VIHEKQTAVS VENFIAELLP DKWFDIGCLV VEDPVHGIHL
ETFTQATPVP LEFVQQAQSL TPQDYNLRWS GLLVTVGEVL EKSLLNVSRT DWHMAFTGMS
RRQMIYSAAR AIAGMYKQRL PPRTV
//