Full text data of CALM3
CALM3
(CALM1, CALM2)
[Confidence: low (only semi-automatic identification from reviews)]
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q96HY3
ID Q96HY3_HUMAN Unreviewed; 113 AA.
AC Q96HY3;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
read moreDT 22-JAN-2014, entry version 103.
DE SubName: Full=CALM1 protein;
DE SubName: Full=Calmodulin;
DE SubName: Full=Calmodulin 2 (Phosphorylase kinase, delta), isoform CRA_a;
DE SubName: Full=Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_a;
DE SubName: Full=LP7057 protein;
GN Name=CALM3; Synonyms=CALM1, CALM2; ORFNames=hCG_17033, hCG_20313;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11181995; DOI=10.1126/science.1058040;
RA Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G.,
RA Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D.,
RA Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q.,
RA Kodira C.D., Zheng X.H., Chen L., Skupski M., Subramanian G.,
RA Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S.,
RA Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J.,
RA Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R.,
RA Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A.,
RA Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K.,
RA Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V.,
RA Brandon R., Cargill M., Chandramouliswaran I., Charlab R.,
RA Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K.,
RA Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z.,
RA Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A.,
RA Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V.,
RA Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B.,
RA Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J.,
RA Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C.,
RA Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L.,
RA Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S.,
RA Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A.,
RA Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D.,
RA Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L.,
RA Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N.,
RA Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S.,
RA Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F.,
RA Kline L., Koduru S., Love A., Mann F., May D., McCawley S.,
RA McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K.,
RA Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M.,
RA Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C.,
RA Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N.,
RA Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M.,
RA Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F.,
RA Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A.,
RA Mi H., Lazareva B., Hatton T., Narechania A., Diemer K.,
RA Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R.,
RA Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J.,
RA Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H.,
RA Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D.,
RA Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A.,
RA Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S.,
RA Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L.,
RA Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W.,
RA McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M.,
RA Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J.,
RA Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E.,
RA Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.;
RT "The sequence of the human genome.";
RL Science 291:1304-1351(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RA Wan D.F., Qin W.X., Zhou X.M., Zhang P.P., Jiang H.Q., Gu J.R.;
RT "Novel human cDNA clones with function of inhibiting growth of liver
RT cancer cells.";
RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12508121; DOI=10.1038/nature01348;
RA Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA Quetier F., Waterston R., Hood L., Weissenbach J.;
RT "The DNA sequence and analysis of human chromosome 14.";
RL Nature 421:601-607(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Primary B-Cells;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M.,
RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S.,
RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F.,
RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J.,
RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N.,
RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B.,
RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B.,
RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S.,
RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R.,
RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L.,
RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E.,
RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D.,
RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G.,
RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J.,
RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L.,
RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D.,
RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A.,
RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S.,
RA Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [6]
RP NUCLEOTIDE SEQUENCE.
RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE.
RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP STRUCTURE BY NMR OF 11-78 IN COMPLEX WITH CALCIUM.
RX PubMed=17473011; DOI=10.1110/ps.072777107;
RA Lakowski T.M., Lee G.M., Okon M., Reid R.E., McIntosh L.P.;
RT "Calcium-induced folding of a fragment of calmodulin composed of EF-
RT hands 2 and 3.";
RL Protein Sci. 16:1119-1132(2007).
RN [9]
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
RN [10]
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2013) to UniProtKB.
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DR EMBL; AC093503; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL512791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC007965; AAH07965.1; -; mRNA.
DR EMBL; AY189287; AAO86731.1; -; mRNA.
DR EMBL; CH471126; EAW57425.1; -; Genomic_DNA.
DR EMBL; CH471053; EAX00220.1; -; Genomic_DNA.
DR EMBL; CH471053; EAX00221.1; -; Genomic_DNA.
DR EMBL; CH471053; EAX00222.1; -; Genomic_DNA.
DR EMBL; CH471053; EAX00223.1; -; Genomic_DNA.
DR RefSeq; XP_005259337.1; XM_005259280.1.
DR UniGene; Hs.282410; -.
DR UniGene; Hs.468442; -.
DR UniGene; Hs.515487; -.
DR PDB; 2HF5; NMR; -; A=11-78.
DR PDBsum; 2HF5; -.
DR Ensembl; ENST00000544280; ENSP00000442853; ENSG00000198668.
DR Ensembl; ENST00000553542; ENSP00000450829; ENSG00000198668.
DR Ensembl; ENST00000594523; ENSP00000468877; ENSG00000160014.
DR Ensembl; ENST00000598871; ENSP00000470502; ENSG00000160014.
DR Ensembl; ENST00000599839; ENSP00000471225; ENSG00000160014.
DR GeneID; 808; -.
DR HGNC; HGNC:1442; CALM1.
DR HGNC; HGNC:1449; CALM3.
DR PharmGKB; PA26035; -.
DR HOGENOM; HOG000233018; -.
DR HOVERGEN; HBG012180; -.
DR ChiTaRS; CALM1; human.
DR NextBio; 13645747; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR GO; GO:0051412; P:response to corticosterone stimulus; IEA:Ensembl.
DR Gene3D; 1.10.238.10; -; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 3.
DR PROSITE; PS00018; EF_HAND_1; 3.
DR PROSITE; PS50222; EF_HAND_2; 3.
PE 1: Evidence at protein level;
KW 3D-structure; Calcium; Complete proteome; Kinase; Metal-binding;
KW Reference proteome; Transferase.
FT METAL 23 23 Calcium 1.
FT METAL 25 25 Calcium 1.
FT METAL 32 32 Calcium 1.
FT METAL 58 58 Calcium 2.
FT METAL 60 60 Calcium 2.
FT METAL 62 62 Calcium 2.
FT METAL 69 69 Calcium 2.
SQ SEQUENCE 113 AA; 12876 MW; B8CDD96451018E44 CRC64;
MRSLGQNPTE AELQDMINEV DADGNGTIDF PEFLTMMARK MKDTDSEEEI REAFRVFDKD
GNGYISAAEL RHVMTNLGEK LTDEEVDEMI READIDGDGQ VNYEEFVQMM TAK
//
ID Q96HY3_HUMAN Unreviewed; 113 AA.
AC Q96HY3;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
read moreDT 22-JAN-2014, entry version 103.
DE SubName: Full=CALM1 protein;
DE SubName: Full=Calmodulin;
DE SubName: Full=Calmodulin 2 (Phosphorylase kinase, delta), isoform CRA_a;
DE SubName: Full=Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_a;
DE SubName: Full=LP7057 protein;
GN Name=CALM3; Synonyms=CALM1, CALM2; ORFNames=hCG_17033, hCG_20313;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11181995; DOI=10.1126/science.1058040;
RA Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G.,
RA Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D.,
RA Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q.,
RA Kodira C.D., Zheng X.H., Chen L., Skupski M., Subramanian G.,
RA Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S.,
RA Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J.,
RA Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R.,
RA Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A.,
RA Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K.,
RA Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V.,
RA Brandon R., Cargill M., Chandramouliswaran I., Charlab R.,
RA Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K.,
RA Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z.,
RA Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A.,
RA Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V.,
RA Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B.,
RA Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J.,
RA Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C.,
RA Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L.,
RA Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S.,
RA Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A.,
RA Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D.,
RA Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L.,
RA Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N.,
RA Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S.,
RA Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F.,
RA Kline L., Koduru S., Love A., Mann F., May D., McCawley S.,
RA McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K.,
RA Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M.,
RA Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C.,
RA Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N.,
RA Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M.,
RA Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F.,
RA Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A.,
RA Mi H., Lazareva B., Hatton T., Narechania A., Diemer K.,
RA Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R.,
RA Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J.,
RA Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H.,
RA Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D.,
RA Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A.,
RA Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S.,
RA Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L.,
RA Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W.,
RA McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M.,
RA Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J.,
RA Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E.,
RA Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.;
RT "The sequence of the human genome.";
RL Science 291:1304-1351(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RA Wan D.F., Qin W.X., Zhou X.M., Zhang P.P., Jiang H.Q., Gu J.R.;
RT "Novel human cDNA clones with function of inhibiting growth of liver
RT cancer cells.";
RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12508121; DOI=10.1038/nature01348;
RA Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA Quetier F., Waterston R., Hood L., Weissenbach J.;
RT "The DNA sequence and analysis of human chromosome 14.";
RL Nature 421:601-607(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Primary B-Cells;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M.,
RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S.,
RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F.,
RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J.,
RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N.,
RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B.,
RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B.,
RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S.,
RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R.,
RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L.,
RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E.,
RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D.,
RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G.,
RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J.,
RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L.,
RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D.,
RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A.,
RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S.,
RA Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [6]
RP NUCLEOTIDE SEQUENCE.
RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE.
RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP STRUCTURE BY NMR OF 11-78 IN COMPLEX WITH CALCIUM.
RX PubMed=17473011; DOI=10.1110/ps.072777107;
RA Lakowski T.M., Lee G.M., Okon M., Reid R.E., McIntosh L.P.;
RT "Calcium-induced folding of a fragment of calmodulin composed of EF-
RT hands 2 and 3.";
RL Protein Sci. 16:1119-1132(2007).
RN [9]
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
RN [10]
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2013) to UniProtKB.
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DR EMBL; AC093503; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL512791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC007965; AAH07965.1; -; mRNA.
DR EMBL; AY189287; AAO86731.1; -; mRNA.
DR EMBL; CH471126; EAW57425.1; -; Genomic_DNA.
DR EMBL; CH471053; EAX00220.1; -; Genomic_DNA.
DR EMBL; CH471053; EAX00221.1; -; Genomic_DNA.
DR EMBL; CH471053; EAX00222.1; -; Genomic_DNA.
DR EMBL; CH471053; EAX00223.1; -; Genomic_DNA.
DR RefSeq; XP_005259337.1; XM_005259280.1.
DR UniGene; Hs.282410; -.
DR UniGene; Hs.468442; -.
DR UniGene; Hs.515487; -.
DR PDB; 2HF5; NMR; -; A=11-78.
DR PDBsum; 2HF5; -.
DR Ensembl; ENST00000544280; ENSP00000442853; ENSG00000198668.
DR Ensembl; ENST00000553542; ENSP00000450829; ENSG00000198668.
DR Ensembl; ENST00000594523; ENSP00000468877; ENSG00000160014.
DR Ensembl; ENST00000598871; ENSP00000470502; ENSG00000160014.
DR Ensembl; ENST00000599839; ENSP00000471225; ENSG00000160014.
DR GeneID; 808; -.
DR HGNC; HGNC:1442; CALM1.
DR HGNC; HGNC:1449; CALM3.
DR PharmGKB; PA26035; -.
DR HOGENOM; HOG000233018; -.
DR HOVERGEN; HBG012180; -.
DR ChiTaRS; CALM1; human.
DR NextBio; 13645747; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR GO; GO:0051412; P:response to corticosterone stimulus; IEA:Ensembl.
DR Gene3D; 1.10.238.10; -; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 3.
DR PROSITE; PS00018; EF_HAND_1; 3.
DR PROSITE; PS50222; EF_HAND_2; 3.
PE 1: Evidence at protein level;
KW 3D-structure; Calcium; Complete proteome; Kinase; Metal-binding;
KW Reference proteome; Transferase.
FT METAL 23 23 Calcium 1.
FT METAL 25 25 Calcium 1.
FT METAL 32 32 Calcium 1.
FT METAL 58 58 Calcium 2.
FT METAL 60 60 Calcium 2.
FT METAL 62 62 Calcium 2.
FT METAL 69 69 Calcium 2.
SQ SEQUENCE 113 AA; 12876 MW; B8CDD96451018E44 CRC64;
MRSLGQNPTE AELQDMINEV DADGNGTIDF PEFLTMMARK MKDTDSEEEI REAFRVFDKD
GNGYISAAEL RHVMTNLGEK LTDEEVDEMI READIDGDGQ VNYEEFVQMM TAK
//