Full text data of H4
H4
[Confidence: low (only semi-automatic identification from reviews)]
UniProt
Q96LD9
ID Q96LD9_HUMAN Unreviewed; 390 AA.
AC Q96LD9;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
read moreDT 22-JAN-2014, entry version 64.
DE SubName: Full=Histamine receptor H4;
GN Name=H4;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11179435;
RA Nguyen T., Shapiro D.A., George S.R., Setola V., Lee D.K., Cheng R.,
RA Rauser L., Lee S.P., Lynch K.R., Roth B.L., O'Dowd B.F.;
RT "Discovery of a novel member of the histamine receptor family.";
RL Mol. Pharmacol. 59:427-433(2001).
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
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DR EMBL; AY008280; AAL09297.1; -; mRNA.
DR UniGene; Hs.287388; -.
DR ProteinModelPortal; Q96LD9; -.
DR HOVERGEN; HBG102132; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0004969; F:histamine receptor activity; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:InterPro.
DR GO; GO:0043408; P:regulation of MAPK cascade; IEA:InterPro.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR008102; Histamine_H4_rcpt.
DR PANTHER; PTHR24249:SF55; PTHR24249:SF55; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01726; HISTAMINEH4R.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW G-protein coupled receptor; Membrane; Receptor; Transducer;
KW Transmembrane.
SQ SEQUENCE 390 AA; 44470 MW; CC82B5D30D216C66 CRC64;
MADTNSTINL SLSTRVTLAF FMSLVAFAIM LGNALVILAF VVDKNLRHRS SYFFLNLAIS
DFFVGVISIP LYIPHTLFEW DFGKEICVFW LTTDYLLCTA SVYNIVLISY DRYLSVSNAV
SYRTQHTGVL KIVTLMVAVW VLAFLVNGPM ILVSESWKDE GSECEPGFFS EWYILAITSF
LEFVIPVILV AYFNMNIYWS LWKRDHLSRC QSHPGLTAVS SNICGHSFRG RLSSRRSLSA
STEVPASFHS ERQRRKSSLM FSSRTKMNSN TIASKMGSFS QSDSVALHQR EHVELLRARR
LAKSLAILLG VFAVCWAPYS LFTIVLSFYS SATGPKSVWY RIAFWLQWFN SFVNPLLYPL
CHKRFQKAFL KIFCIKKQPL PSQHSRSVSS
//
ID Q96LD9_HUMAN Unreviewed; 390 AA.
AC Q96LD9;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
read moreDT 22-JAN-2014, entry version 64.
DE SubName: Full=Histamine receptor H4;
GN Name=H4;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11179435;
RA Nguyen T., Shapiro D.A., George S.R., Setola V., Lee D.K., Cheng R.,
RA Rauser L., Lee S.P., Lynch K.R., Roth B.L., O'Dowd B.F.;
RT "Discovery of a novel member of the histamine receptor family.";
RL Mol. Pharmacol. 59:427-433(2001).
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AY008280; AAL09297.1; -; mRNA.
DR UniGene; Hs.287388; -.
DR ProteinModelPortal; Q96LD9; -.
DR HOVERGEN; HBG102132; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0004969; F:histamine receptor activity; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:InterPro.
DR GO; GO:0043408; P:regulation of MAPK cascade; IEA:InterPro.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR008102; Histamine_H4_rcpt.
DR PANTHER; PTHR24249:SF55; PTHR24249:SF55; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01726; HISTAMINEH4R.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW G-protein coupled receptor; Membrane; Receptor; Transducer;
KW Transmembrane.
SQ SEQUENCE 390 AA; 44470 MW; CC82B5D30D216C66 CRC64;
MADTNSTINL SLSTRVTLAF FMSLVAFAIM LGNALVILAF VVDKNLRHRS SYFFLNLAIS
DFFVGVISIP LYIPHTLFEW DFGKEICVFW LTTDYLLCTA SVYNIVLISY DRYLSVSNAV
SYRTQHTGVL KIVTLMVAVW VLAFLVNGPM ILVSESWKDE GSECEPGFFS EWYILAITSF
LEFVIPVILV AYFNMNIYWS LWKRDHLSRC QSHPGLTAVS SNICGHSFRG RLSSRRSLSA
STEVPASFHS ERQRRKSSLM FSSRTKMNSN TIASKMGSFS QSDSVALHQR EHVELLRARR
LAKSLAILLG VFAVCWAPYS LFTIVLSFYS SATGPKSVWY RIAFWLQWFN SFVNPLLYPL
CHKRFQKAFL KIFCIKKQPL PSQHSRSVSS
//