Full text data of RABL3
RABL3
[Confidence: low (only semi-automatic identification from reviews)]
Rab-like protein 3
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Rab-like protein 3
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q5HYI8
ID RABL3_HUMAN Reviewed; 236 AA.
AC Q5HYI8; Q8WUD3;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
read moreDT 15-FEB-2005, sequence version 1.
DT 22-JAN-2014, entry version 90.
DE RecName: Full=Rab-like protein 3;
GN Name=RABL3;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Bone marrow, Fetal skin, and Heart;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,
RA Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,
RA Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AK293085; BAF85774.1; -; mRNA.
DR EMBL; BX647664; CAI46059.1; -; mRNA.
DR EMBL; BX647593; CAI46064.1; -; mRNA.
DR EMBL; BX647559; CAI46095.1; -; mRNA.
DR EMBL; CH471052; EAW79521.1; -; Genomic_DNA.
DR EMBL; BC020832; AAH20832.1; -; mRNA.
DR RefSeq; NP_776186.2; NM_173825.3.
DR UniGene; Hs.444360; -.
DR ProteinModelPortal; Q5HYI8; -.
DR SMR; Q5HYI8; 6-205.
DR IntAct; Q5HYI8; 1.
DR PhosphoSite; Q5HYI8; -.
DR DMDM; 74762186; -.
DR PaxDb; Q5HYI8; -.
DR PRIDE; Q5HYI8; -.
DR DNASU; 285282; -.
DR Ensembl; ENST00000273375; ENSP00000273375; ENSG00000144840.
DR GeneID; 285282; -.
DR KEGG; hsa:285282; -.
DR UCSC; uc003edx.3; human.
DR CTD; 285282; -.
DR GeneCards; GC03M120405; -.
DR HGNC; HGNC:18072; RABL3.
DR HPA; HPA035151; -.
DR neXtProt; NX_Q5HYI8; -.
DR PharmGKB; PA34161; -.
DR eggNOG; NOG79707; -.
DR HOGENOM; HOG000006785; -.
DR HOVERGEN; HBG108392; -.
DR InParanoid; Q5HYI8; -.
DR KO; K07933; -.
DR OMA; HLLCHNQ; -.
DR OrthoDB; EOG76473G; -.
DR PhylomeDB; Q5HYI8; -.
DR GenomeRNAi; 285282; -.
DR NextBio; 95404; -.
DR PRO; PR:Q5HYI8; -.
DR ArrayExpress; Q5HYI8; -.
DR Bgee; Q5HYI8; -.
DR CleanEx; HS_RABL3; -.
DR Genevestigator; Q5HYI8; -.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001806; Small_GTPase.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51419; RAB; FALSE_NEG.
PE 1: Evidence at protein level;
KW Complete proteome; GTP-binding; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1 236 Rab-like protein 3.
FT /FTId=PRO_0000312166.
FT NP_BIND 13 20 GTP (By similarity).
FT NP_BIND 66 70 GTP (By similarity).
FT NP_BIND 147 150 GTP (By similarity).
FT REGION 1 236 Small GTPase-like.
FT CONFLICT 60 60 Y -> C (in Ref. 4; AAH20832).
FT CONFLICT 163 163 R -> T (in Ref. 4; AAH20832).
SQ SEQUENCE 236 AA; 26423 MW; B80898B1293C88C6 CRC64;
MASLDRVKVL VLGDSGVGKS SLVHLLCQNQ VLGNPSWTVG CSVDVRVHDY KEGTPEEKTY
YIELWDVGGS VGSASSVKST RAVFYNSVNG IIFVHDLTNK KSSQNLRRWS LEALNRDLVP
TGVLVTNGDY DQEQFADNQI PLLVIGTKLD QIHETKRHEV LTRTAFLAED FNPEEINLDC
TNPRYLAAGS SNAVKLSRFF DKVIEKRYFL REGNQIPGFP DRKRFGAGTL KSLHYD
//
ID RABL3_HUMAN Reviewed; 236 AA.
AC Q5HYI8; Q8WUD3;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
read moreDT 15-FEB-2005, sequence version 1.
DT 22-JAN-2014, entry version 90.
DE RecName: Full=Rab-like protein 3;
GN Name=RABL3;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Bone marrow, Fetal skin, and Heart;
RX PubMed=17974005; DOI=10.1186/1471-2164-8-399;
RA Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
RA Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,
RA Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,
RA Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;
RT "The full-ORF clone resource of the German cDNA consortium.";
RL BMC Genomics 8:399-399(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AK293085; BAF85774.1; -; mRNA.
DR EMBL; BX647664; CAI46059.1; -; mRNA.
DR EMBL; BX647593; CAI46064.1; -; mRNA.
DR EMBL; BX647559; CAI46095.1; -; mRNA.
DR EMBL; CH471052; EAW79521.1; -; Genomic_DNA.
DR EMBL; BC020832; AAH20832.1; -; mRNA.
DR RefSeq; NP_776186.2; NM_173825.3.
DR UniGene; Hs.444360; -.
DR ProteinModelPortal; Q5HYI8; -.
DR SMR; Q5HYI8; 6-205.
DR IntAct; Q5HYI8; 1.
DR PhosphoSite; Q5HYI8; -.
DR DMDM; 74762186; -.
DR PaxDb; Q5HYI8; -.
DR PRIDE; Q5HYI8; -.
DR DNASU; 285282; -.
DR Ensembl; ENST00000273375; ENSP00000273375; ENSG00000144840.
DR GeneID; 285282; -.
DR KEGG; hsa:285282; -.
DR UCSC; uc003edx.3; human.
DR CTD; 285282; -.
DR GeneCards; GC03M120405; -.
DR HGNC; HGNC:18072; RABL3.
DR HPA; HPA035151; -.
DR neXtProt; NX_Q5HYI8; -.
DR PharmGKB; PA34161; -.
DR eggNOG; NOG79707; -.
DR HOGENOM; HOG000006785; -.
DR HOVERGEN; HBG108392; -.
DR InParanoid; Q5HYI8; -.
DR KO; K07933; -.
DR OMA; HLLCHNQ; -.
DR OrthoDB; EOG76473G; -.
DR PhylomeDB; Q5HYI8; -.
DR GenomeRNAi; 285282; -.
DR NextBio; 95404; -.
DR PRO; PR:Q5HYI8; -.
DR ArrayExpress; Q5HYI8; -.
DR Bgee; Q5HYI8; -.
DR CleanEx; HS_RABL3; -.
DR Genevestigator; Q5HYI8; -.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001806; Small_GTPase.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51419; RAB; FALSE_NEG.
PE 1: Evidence at protein level;
KW Complete proteome; GTP-binding; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1 236 Rab-like protein 3.
FT /FTId=PRO_0000312166.
FT NP_BIND 13 20 GTP (By similarity).
FT NP_BIND 66 70 GTP (By similarity).
FT NP_BIND 147 150 GTP (By similarity).
FT REGION 1 236 Small GTPase-like.
FT CONFLICT 60 60 Y -> C (in Ref. 4; AAH20832).
FT CONFLICT 163 163 R -> T (in Ref. 4; AAH20832).
SQ SEQUENCE 236 AA; 26423 MW; B80898B1293C88C6 CRC64;
MASLDRVKVL VLGDSGVGKS SLVHLLCQNQ VLGNPSWTVG CSVDVRVHDY KEGTPEEKTY
YIELWDVGGS VGSASSVKST RAVFYNSVNG IIFVHDLTNK KSSQNLRRWS LEALNRDLVP
TGVLVTNGDY DQEQFADNQI PLLVIGTKLD QIHETKRHEV LTRTAFLAED FNPEEINLDC
TNPRYLAAGS SNAVKLSRFF DKVIEKRYFL REGNQIPGFP DRKRFGAGTL KSLHYD
//