Full text data of RFESD
RFESD
[Confidence: low (only semi-automatic identification from reviews)]
Rieske domain-containing protein
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Rieske domain-containing protein
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q8TAC1
ID RFESD_HUMAN Reviewed; 157 AA.
AC Q8TAC1; J3KPH1;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-JUN-2002, sequence version 1.
DT 22-JAN-2014, entry version 85.
DE RecName: Full=Rieske domain-containing protein;
GN Name=RFESD;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15372022; DOI=10.1038/nature02919;
RA Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT "The DNA sequence and comparative analysis of human chromosome 5.";
RL Nature 431:268-274(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Brain, Lung, and Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-153 (ISOFORM 2).
RC TISSUE=Fetal pancreas;
RA Melton D., Brown J., Kenty G., Permutt A., Lee C., Kaestner K.,
RA Lemishka I., Scearce M., Brestelli J., Gradwohl G., Clifton S.,
RA Hillier L., Marra M., Pape D., Wylie T., Martin J., Blistain A.,
RA Schmitt A., Theising B., Ritter E., Ronko I., Bennett J., Cardenas M.,
RA Gibbons M., McCann R., Cole R., Tsagareishvili R., Williams T.,
RA Jackson Y., Bowers Y.;
RT "Endocrine pancreas consortium.";
RL Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [6]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND MASS SPECTROMETRY.
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E.,
RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K.,
RA Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-
RT terminal acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- COFACTOR: Binds 1 2Fe-2S cluster per subunit (By similarity).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8TAC1-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8TAC1-2; Sequence=VSP_044452;
CC Note=No experimental confirmation available;
CC -!- SIMILARITY: Contains 2 Rieske domains.
CC -----------------------------------------------------------------------
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CC Distributed under the Creative Commons Attribution-NoDerivs License
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DR EMBL; AC008547; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471084; EAW96043.1; -; Genomic_DNA.
DR EMBL; CH471084; EAW96045.1; -; Genomic_DNA.
DR EMBL; BC024023; AAH24023.1; -; mRNA.
DR EMBL; BC035110; AAH35110.1; -; mRNA.
DR EMBL; BC048979; AAH48979.1; -; mRNA.
DR EMBL; BM263054; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_001124537.1; NM_001131065.1.
DR RefSeq; NP_001124538.1; NM_001131066.1.
DR RefSeq; NP_775498.1; NM_173362.3.
DR RefSeq; XP_005272030.1; XM_005271973.1.
DR UniGene; Hs.399758; -.
DR ProteinModelPortal; Q8TAC1; -.
DR SMR; Q8TAC1; 14-154.
DR STRING; 9606.ENSP00000369341; -.
DR PhosphoSite; Q8TAC1; -.
DR DMDM; 74730342; -.
DR PaxDb; Q8TAC1; -.
DR PRIDE; Q8TAC1; -.
DR DNASU; 317671; -.
DR Ensembl; ENST00000311364; ENSP00000309229; ENSG00000175449.
DR Ensembl; ENST00000380005; ENSP00000369341; ENSG00000175449.
DR Ensembl; ENST00000458310; ENSP00000413592; ENSG00000175449.
DR GeneID; 317671; -.
DR KEGG; hsa:317671; -.
DR UCSC; uc003klf.3; human.
DR CTD; 317671; -.
DR GeneCards; GC05P094982; -.
DR HGNC; HGNC:29587; RFESD.
DR HPA; CAB016546; -.
DR neXtProt; NX_Q8TAC1; -.
DR PharmGKB; PA162401171; -.
DR eggNOG; NOG45762; -.
DR HOGENOM; HOG000128541; -.
DR HOVERGEN; HBG061590; -.
DR InParanoid; Q8TAC1; -.
DR OMA; WCSKGVK; -.
DR PhylomeDB; Q8TAC1; -.
DR GenomeRNAi; 317671; -.
DR NextBio; 35535124; -.
DR PRO; PR:Q8TAC1; -.
DR ArrayExpress; Q8TAC1; -.
DR Bgee; Q8TAC1; -.
DR CleanEx; HS_RFESD; -.
DR Genevestigator; Q8TAC1; -.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 2.102.10.10; -; 1.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR SUPFAM; SSF50022; SSF50022; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 1: Evidence at protein level;
KW 2Fe-2S; Acetylation; Alternative splicing; Complete proteome; Iron;
KW Iron-sulfur; Metal-binding; Reference proteome; Repeat.
FT CHAIN 1 157 Rieske domain-containing protein.
FT /FTId=PRO_0000313813.
FT DOMAIN 16 94 Rieske 1.
FT DOMAIN 17 131 Rieske 2.
FT METAL 57 57 Iron-sulfur (2Fe-2S) (By similarity).
FT METAL 59 59 Iron-sulfur (2Fe-2S); via pros nitrogen
FT (By similarity).
FT METAL 80 80 Iron-sulfur (2Fe-2S) (By similarity).
FT METAL 83 83 Iron-sulfur (2Fe-2S); via pros nitrogen
FT (By similarity).
FT MOD_RES 1 1 N-acetylmethionine.
FT VAR_SEQ 1 1 M -> MLKCFRNCLRPSSLSTLPLQYGILFPKLLACLVHLH
FT FGHFSSAVISVTSFYLSM (in isoform 2).
FT /FTId=VSP_044452.
SQ SEQUENCE 157 AA; 17762 MW; E959948673E776F8 CRC64;
MNLDGSAQDP EKREYSSVCV GREDDIKKSE RMTAVVHDRE VVIFYHKGEY HAMDIRCYHS
GGPLHLGDIE DFDGRPCIVC PWHKYKITLA TGEGLYQSIN PKDPSAKPKW CSKGIKQRIH
TVTVDNGNIY VTLSNEPFKC DSDFYATGDF KVIKSSS
//
ID RFESD_HUMAN Reviewed; 157 AA.
AC Q8TAC1; J3KPH1;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-JUN-2002, sequence version 1.
DT 22-JAN-2014, entry version 85.
DE RecName: Full=Rieske domain-containing protein;
GN Name=RFESD;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15372022; DOI=10.1038/nature02919;
RA Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT "The DNA sequence and comparative analysis of human chromosome 5.";
RL Nature 431:268-274(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Brain, Lung, and Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-153 (ISOFORM 2).
RC TISSUE=Fetal pancreas;
RA Melton D., Brown J., Kenty G., Permutt A., Lee C., Kaestner K.,
RA Lemishka I., Scearce M., Brestelli J., Gradwohl G., Clifton S.,
RA Hillier L., Marra M., Pape D., Wylie T., Martin J., Blistain A.,
RA Schmitt A., Theising B., Ritter E., Ronko I., Bennett J., Cardenas M.,
RA Gibbons M., McCann R., Cole R., Tsagareishvili R., Williams T.,
RA Jackson Y., Bowers Y.;
RT "Endocrine pancreas consortium.";
RL Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [6]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND MASS SPECTROMETRY.
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E.,
RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K.,
RA Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-
RT terminal acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- COFACTOR: Binds 1 2Fe-2S cluster per subunit (By similarity).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8TAC1-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8TAC1-2; Sequence=VSP_044452;
CC Note=No experimental confirmation available;
CC -!- SIMILARITY: Contains 2 Rieske domains.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AC008547; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471084; EAW96043.1; -; Genomic_DNA.
DR EMBL; CH471084; EAW96045.1; -; Genomic_DNA.
DR EMBL; BC024023; AAH24023.1; -; mRNA.
DR EMBL; BC035110; AAH35110.1; -; mRNA.
DR EMBL; BC048979; AAH48979.1; -; mRNA.
DR EMBL; BM263054; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_001124537.1; NM_001131065.1.
DR RefSeq; NP_001124538.1; NM_001131066.1.
DR RefSeq; NP_775498.1; NM_173362.3.
DR RefSeq; XP_005272030.1; XM_005271973.1.
DR UniGene; Hs.399758; -.
DR ProteinModelPortal; Q8TAC1; -.
DR SMR; Q8TAC1; 14-154.
DR STRING; 9606.ENSP00000369341; -.
DR PhosphoSite; Q8TAC1; -.
DR DMDM; 74730342; -.
DR PaxDb; Q8TAC1; -.
DR PRIDE; Q8TAC1; -.
DR DNASU; 317671; -.
DR Ensembl; ENST00000311364; ENSP00000309229; ENSG00000175449.
DR Ensembl; ENST00000380005; ENSP00000369341; ENSG00000175449.
DR Ensembl; ENST00000458310; ENSP00000413592; ENSG00000175449.
DR GeneID; 317671; -.
DR KEGG; hsa:317671; -.
DR UCSC; uc003klf.3; human.
DR CTD; 317671; -.
DR GeneCards; GC05P094982; -.
DR HGNC; HGNC:29587; RFESD.
DR HPA; CAB016546; -.
DR neXtProt; NX_Q8TAC1; -.
DR PharmGKB; PA162401171; -.
DR eggNOG; NOG45762; -.
DR HOGENOM; HOG000128541; -.
DR HOVERGEN; HBG061590; -.
DR InParanoid; Q8TAC1; -.
DR OMA; WCSKGVK; -.
DR PhylomeDB; Q8TAC1; -.
DR GenomeRNAi; 317671; -.
DR NextBio; 35535124; -.
DR PRO; PR:Q8TAC1; -.
DR ArrayExpress; Q8TAC1; -.
DR Bgee; Q8TAC1; -.
DR CleanEx; HS_RFESD; -.
DR Genevestigator; Q8TAC1; -.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 2.102.10.10; -; 1.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR SUPFAM; SSF50022; SSF50022; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 1: Evidence at protein level;
KW 2Fe-2S; Acetylation; Alternative splicing; Complete proteome; Iron;
KW Iron-sulfur; Metal-binding; Reference proteome; Repeat.
FT CHAIN 1 157 Rieske domain-containing protein.
FT /FTId=PRO_0000313813.
FT DOMAIN 16 94 Rieske 1.
FT DOMAIN 17 131 Rieske 2.
FT METAL 57 57 Iron-sulfur (2Fe-2S) (By similarity).
FT METAL 59 59 Iron-sulfur (2Fe-2S); via pros nitrogen
FT (By similarity).
FT METAL 80 80 Iron-sulfur (2Fe-2S) (By similarity).
FT METAL 83 83 Iron-sulfur (2Fe-2S); via pros nitrogen
FT (By similarity).
FT MOD_RES 1 1 N-acetylmethionine.
FT VAR_SEQ 1 1 M -> MLKCFRNCLRPSSLSTLPLQYGILFPKLLACLVHLH
FT FGHFSSAVISVTSFYLSM (in isoform 2).
FT /FTId=VSP_044452.
SQ SEQUENCE 157 AA; 17762 MW; E959948673E776F8 CRC64;
MNLDGSAQDP EKREYSSVCV GREDDIKKSE RMTAVVHDRE VVIFYHKGEY HAMDIRCYHS
GGPLHLGDIE DFDGRPCIVC PWHKYKITLA TGEGLYQSIN PKDPSAKPKW CSKGIKQRIH
TVTVDNGNIY VTLSNEPFKC DSDFYATGDF KVIKSSS
//