Full text data of RPS25
RPS25
[Confidence: low (only semi-automatic identification from reviews)]
40S ribosomal protein S25
Note: presumably soluble (membrane word is not in UniProt keywords or features)
40S ribosomal protein S25
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
P62851
ID RS25_HUMAN Reviewed; 125 AA.
AC P62851; B2R4M7; P25111;
DT 16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
read moreDT 16-AUG-2004, sequence version 1.
DT 22-JAN-2014, entry version 97.
DE RecName: Full=40S ribosomal protein S25;
GN Name=RPS25;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1748303; DOI=10.1016/0378-1119(91)90335-9;
RA Li M., Latoud C., Center M.S.;
RT "Cloning and sequencing a cDNA encoding human ribosomal protein S25.";
RL Gene 107:329-333(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875025; DOI=10.1101/gr.214202;
RA Yoshihama M., Uechi T., Asakawa S., Kawasaki K., Kato S., Higa S.,
RA Maeda N., Minoshima S., Tanaka T., Shimizu N., Kenmochi N.;
RT "The human ribosomal protein genes: sequencing and comparative
RT analysis of 73 genes.";
RL Genome Res. 12:379-390(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Tongue;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Pancreas, and Skin;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [6]
RP PROTEIN SEQUENCE OF 103-114.
RC TISSUE=Placenta;
RX PubMed=8706699; DOI=10.1111/j.1432-1033.1996.0144u.x;
RA Vladimirov S.N., Ivanov A.V., Karpova G.G., Musolyamov A.K.,
RA Egorov T.A., Thiede B., Wittmann-Liebold B., Otto A.;
RT "Characterization of the human small-ribosomal-subunit proteins by N-
RT terminal and internal sequencing, and mass spectrometry.";
RL Eur. J. Biochem. 239:144-149(1996).
RN [7]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-52; LYS-60; LYS-66 AND
RP LYS-94, AND MASS SPECTROMETRY.
RX PubMed=19608861; DOI=10.1126/science.1175371;
RA Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M.,
RA Walther T.C., Olsen J.V., Mann M.;
RT "Lysine acetylation targets protein complexes and co-regulates major
RT cellular functions.";
RL Science 325:834-840(2009).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [9]
RP STRUCTURE BY ELECTRON MICROSCOPY (5.0 ANGSTROMS).
RX PubMed=23636399; DOI=10.1038/nature12104;
RA Anger A.M., Armache J.P., Berninghausen O., Habeck M., Subklewe M.,
RA Wilson D.N., Beckmann R.;
RT "Structures of the human and Drosophila 80S ribosome.";
RL Nature 497:80-85(2013).
CC -!- INTERACTION:
CC Q9HAU5:UPF2; NbExp=1; IntAct=EBI-353054, EBI-372073;
CC -!- SIMILARITY: Belongs to the ribosomal protein S25e family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; M64716; AAA16105.1; -; mRNA.
DR EMBL; AB061844; BAB79482.1; -; Genomic_DNA.
DR EMBL; AK311883; BAG34824.1; -; mRNA.
DR EMBL; CH471065; EAW67426.1; -; Genomic_DNA.
DR EMBL; BC003537; AAH03537.1; -; mRNA.
DR EMBL; BC004294; AAH04294.1; -; mRNA.
DR EMBL; BC004986; AAH04986.1; -; mRNA.
DR PIR; JQ1347; JQ1347.
DR RefSeq; NP_001019.1; NM_001028.2.
DR UniGene; Hs.512676; -.
DR PDB; 3J3A; EM; 5.00 A; Z=1-125.
DR PDBsum; 3J3A; -.
DR ProteinModelPortal; P62851; -.
DR SMR; P62851; 41-115.
DR IntAct; P62851; 15.
DR MINT; MINT-5000124; -.
DR STRING; 9606.ENSP00000236900; -.
DR PhosphoSite; P62851; -.
DR DMDM; 51338648; -.
DR PaxDb; P62851; -.
DR PRIDE; P62851; -.
DR DNASU; 6230; -.
DR Ensembl; ENST00000527673; ENSP00000435096; ENSG00000118181.
DR Ensembl; ENST00000573464; ENSP00000460242; ENSG00000262088.
DR GeneID; 6230; -.
DR KEGG; hsa:6230; -.
DR UCSC; uc001pun.2; human.
DR CTD; 6230; -.
DR GeneCards; GC11M118886; -.
DR HGNC; HGNC:10413; RPS25.
DR HPA; HPA031801; -.
DR MIM; 180465; gene.
DR neXtProt; NX_P62851; -.
DR PharmGKB; PA34817; -.
DR eggNOG; COG4901; -.
DR HOGENOM; HOG000203673; -.
DR HOVERGEN; HBG054579; -.
DR InParanoid; P62851; -.
DR KO; K02975; -.
DR OMA; QLIYTRS; -.
DR PhylomeDB; P62851; -.
DR Reactome; REACT_116125; Disease.
DR Reactome; REACT_17015; Metabolism of proteins.
DR Reactome; REACT_1762; 3' -UTR-mediated translational regulation.
DR Reactome; REACT_21257; Metabolism of RNA.
DR Reactome; REACT_71; Gene Expression.
DR ChiTaRS; RPS25; human.
DR GeneWiki; RPS25; -.
DR GenomeRNAi; 6230; -.
DR NextBio; 24185; -.
DR PRO; PR:P62851; -.
DR ArrayExpress; P62851; -.
DR Bgee; P62851; -.
DR CleanEx; HS_RPS25; -.
DR Genevestigator; P62851; -.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0005730; C:nucleolus; IDA:UniProtKB.
DR GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:Ensembl.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR GO; GO:0000028; P:ribosomal small subunit assembly; IEA:Ensembl.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR GO; GO:0006415; P:translational termination; TAS:Reactome.
DR GO; GO:0019083; P:viral transcription; TAS:Reactome.
DR InterPro; IPR004977; Ribosomal_S25.
DR PANTHER; PTHR12850; PTHR12850; 1.
DR Pfam; PF03297; Ribosomal_S25; 1.
DR ProDom; PD012268; Ribosomal_S25; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Complete proteome;
KW Direct protein sequencing; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT CHAIN 1 125 40S ribosomal protein S25.
FT /FTId=PRO_0000192869.
FT MOD_RES 52 52 N6-acetyllysine.
FT MOD_RES 60 60 N6-acetyllysine.
FT MOD_RES 66 66 N6-acetyllysine.
FT MOD_RES 94 94 N6-acetyllysine.
SQ SEQUENCE 125 AA; 13742 MW; B8E05F04FCF2F1A9 CRC64;
MPPKDDKKKK DAGKSAKKDK DPVNKSGGKA KKKKWSKGKV RDKLNNLVLF DKATYDKLCK
EVPNYKLITP AVVSERLKIR GSLARAALQE LLSKGLIKLV SKHRAQVIYT RNTKGGDAPA
AGEDA
//
ID RS25_HUMAN Reviewed; 125 AA.
AC P62851; B2R4M7; P25111;
DT 16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
read moreDT 16-AUG-2004, sequence version 1.
DT 22-JAN-2014, entry version 97.
DE RecName: Full=40S ribosomal protein S25;
GN Name=RPS25;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1748303; DOI=10.1016/0378-1119(91)90335-9;
RA Li M., Latoud C., Center M.S.;
RT "Cloning and sequencing a cDNA encoding human ribosomal protein S25.";
RL Gene 107:329-333(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875025; DOI=10.1101/gr.214202;
RA Yoshihama M., Uechi T., Asakawa S., Kawasaki K., Kato S., Higa S.,
RA Maeda N., Minoshima S., Tanaka T., Shimizu N., Kenmochi N.;
RT "The human ribosomal protein genes: sequencing and comparative
RT analysis of 73 genes.";
RL Genome Res. 12:379-390(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Tongue;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Pancreas, and Skin;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [6]
RP PROTEIN SEQUENCE OF 103-114.
RC TISSUE=Placenta;
RX PubMed=8706699; DOI=10.1111/j.1432-1033.1996.0144u.x;
RA Vladimirov S.N., Ivanov A.V., Karpova G.G., Musolyamov A.K.,
RA Egorov T.A., Thiede B., Wittmann-Liebold B., Otto A.;
RT "Characterization of the human small-ribosomal-subunit proteins by N-
RT terminal and internal sequencing, and mass spectrometry.";
RL Eur. J. Biochem. 239:144-149(1996).
RN [7]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-52; LYS-60; LYS-66 AND
RP LYS-94, AND MASS SPECTROMETRY.
RX PubMed=19608861; DOI=10.1126/science.1175371;
RA Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M.,
RA Walther T.C., Olsen J.V., Mann M.;
RT "Lysine acetylation targets protein complexes and co-regulates major
RT cellular functions.";
RL Science 325:834-840(2009).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [9]
RP STRUCTURE BY ELECTRON MICROSCOPY (5.0 ANGSTROMS).
RX PubMed=23636399; DOI=10.1038/nature12104;
RA Anger A.M., Armache J.P., Berninghausen O., Habeck M., Subklewe M.,
RA Wilson D.N., Beckmann R.;
RT "Structures of the human and Drosophila 80S ribosome.";
RL Nature 497:80-85(2013).
CC -!- INTERACTION:
CC Q9HAU5:UPF2; NbExp=1; IntAct=EBI-353054, EBI-372073;
CC -!- SIMILARITY: Belongs to the ribosomal protein S25e family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; M64716; AAA16105.1; -; mRNA.
DR EMBL; AB061844; BAB79482.1; -; Genomic_DNA.
DR EMBL; AK311883; BAG34824.1; -; mRNA.
DR EMBL; CH471065; EAW67426.1; -; Genomic_DNA.
DR EMBL; BC003537; AAH03537.1; -; mRNA.
DR EMBL; BC004294; AAH04294.1; -; mRNA.
DR EMBL; BC004986; AAH04986.1; -; mRNA.
DR PIR; JQ1347; JQ1347.
DR RefSeq; NP_001019.1; NM_001028.2.
DR UniGene; Hs.512676; -.
DR PDB; 3J3A; EM; 5.00 A; Z=1-125.
DR PDBsum; 3J3A; -.
DR ProteinModelPortal; P62851; -.
DR SMR; P62851; 41-115.
DR IntAct; P62851; 15.
DR MINT; MINT-5000124; -.
DR STRING; 9606.ENSP00000236900; -.
DR PhosphoSite; P62851; -.
DR DMDM; 51338648; -.
DR PaxDb; P62851; -.
DR PRIDE; P62851; -.
DR DNASU; 6230; -.
DR Ensembl; ENST00000527673; ENSP00000435096; ENSG00000118181.
DR Ensembl; ENST00000573464; ENSP00000460242; ENSG00000262088.
DR GeneID; 6230; -.
DR KEGG; hsa:6230; -.
DR UCSC; uc001pun.2; human.
DR CTD; 6230; -.
DR GeneCards; GC11M118886; -.
DR HGNC; HGNC:10413; RPS25.
DR HPA; HPA031801; -.
DR MIM; 180465; gene.
DR neXtProt; NX_P62851; -.
DR PharmGKB; PA34817; -.
DR eggNOG; COG4901; -.
DR HOGENOM; HOG000203673; -.
DR HOVERGEN; HBG054579; -.
DR InParanoid; P62851; -.
DR KO; K02975; -.
DR OMA; QLIYTRS; -.
DR PhylomeDB; P62851; -.
DR Reactome; REACT_116125; Disease.
DR Reactome; REACT_17015; Metabolism of proteins.
DR Reactome; REACT_1762; 3' -UTR-mediated translational regulation.
DR Reactome; REACT_21257; Metabolism of RNA.
DR Reactome; REACT_71; Gene Expression.
DR ChiTaRS; RPS25; human.
DR GeneWiki; RPS25; -.
DR GenomeRNAi; 6230; -.
DR NextBio; 24185; -.
DR PRO; PR:P62851; -.
DR ArrayExpress; P62851; -.
DR Bgee; P62851; -.
DR CleanEx; HS_RPS25; -.
DR Genevestigator; P62851; -.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0005730; C:nucleolus; IDA:UniProtKB.
DR GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:Ensembl.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR GO; GO:0000028; P:ribosomal small subunit assembly; IEA:Ensembl.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR GO; GO:0006415; P:translational termination; TAS:Reactome.
DR GO; GO:0019083; P:viral transcription; TAS:Reactome.
DR InterPro; IPR004977; Ribosomal_S25.
DR PANTHER; PTHR12850; PTHR12850; 1.
DR Pfam; PF03297; Ribosomal_S25; 1.
DR ProDom; PD012268; Ribosomal_S25; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Complete proteome;
KW Direct protein sequencing; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT CHAIN 1 125 40S ribosomal protein S25.
FT /FTId=PRO_0000192869.
FT MOD_RES 52 52 N6-acetyllysine.
FT MOD_RES 60 60 N6-acetyllysine.
FT MOD_RES 66 66 N6-acetyllysine.
FT MOD_RES 94 94 N6-acetyllysine.
SQ SEQUENCE 125 AA; 13742 MW; B8E05F04FCF2F1A9 CRC64;
MPPKDDKKKK DAGKSAKKDK DPVNKSGGKA KKKKWSKGKV RDKLNNLVLF DKATYDKLCK
EVPNYKLITP AVVSERLKIR GSLARAALQE LLSKGLIKLV SKHRAQVIYT RNTKGGDAPA
AGEDA
//
MIM
180465
*RECORD*
*FIELD* NO
180465
*FIELD* TI
*180465 RIBOSOMAL PROTEIN S25; RPS25
*FIELD* TX
The mammalian ribosome is composed of 4 RNA species (see 180450) and
read moreapproximately 80 different proteins.
Li et al. (1991) isolated a full-length cDNA clone encoding human
ribosomal protein S25 (RPS25). The cDNA encoded a polypeptide of 125
amino acids with a deduced relative molecular weight of 13,750.
Through generation of sequence tagged sites for chromosome 11, Miwa et
al. (1993) found that 1 cosmid marker contained part of the RPS25 gene.
Imai et al. (1994) further validated its identity and, by direct
fluorescence in situ hybridization, mapped it to 11q23.3. Kenmochi et
al. (1998) confirmed the RPS25 mapping assignment reported by Imai et
al. (1994).
*FIELD* RF
1. Imai, T.; Sudo, K.; Miwa, T.: Assignment of the human ribosomal
protein S25 gene (RPS25) to chromosome 11q23.3 by sequence analysis
of the marker D11S456. Genomics 20: 142-143, 1994.
2. Kenmochi, N.; Kawaguchi, T.; Rozen, S.; Davis, E.; Goodman, N.;
Hudson, T. J.; Tanaka, T.; Page, D. C.: A map of 75 human ribosomal
protein genes. Genome Res. 8: 509-523, 1998.
3. Li, M.; Latoud, C.; Center, M. S.: Cloning and sequencing a cDNA
encoding human ribosomal protein S25. Gene 107: 329-333, 1991.
4. Miwa, T.; Sudo, K.; Nakamura, Y.; Imai, T.: Fifty sequenced-tagged
sites on human chromosome 11. Genomics 17: 211-214, 1993.
*FIELD* CN
Patti M. Sherman - updated: 4/6/1999
*FIELD* CD
Victor A. McKusick: 2/13/1992
*FIELD* ED
carol: 04/16/1999
carol: 4/6/1994
supermim: 3/16/1992
carol: 2/13/1992
*RECORD*
*FIELD* NO
180465
*FIELD* TI
*180465 RIBOSOMAL PROTEIN S25; RPS25
*FIELD* TX
The mammalian ribosome is composed of 4 RNA species (see 180450) and
read moreapproximately 80 different proteins.
Li et al. (1991) isolated a full-length cDNA clone encoding human
ribosomal protein S25 (RPS25). The cDNA encoded a polypeptide of 125
amino acids with a deduced relative molecular weight of 13,750.
Through generation of sequence tagged sites for chromosome 11, Miwa et
al. (1993) found that 1 cosmid marker contained part of the RPS25 gene.
Imai et al. (1994) further validated its identity and, by direct
fluorescence in situ hybridization, mapped it to 11q23.3. Kenmochi et
al. (1998) confirmed the RPS25 mapping assignment reported by Imai et
al. (1994).
*FIELD* RF
1. Imai, T.; Sudo, K.; Miwa, T.: Assignment of the human ribosomal
protein S25 gene (RPS25) to chromosome 11q23.3 by sequence analysis
of the marker D11S456. Genomics 20: 142-143, 1994.
2. Kenmochi, N.; Kawaguchi, T.; Rozen, S.; Davis, E.; Goodman, N.;
Hudson, T. J.; Tanaka, T.; Page, D. C.: A map of 75 human ribosomal
protein genes. Genome Res. 8: 509-523, 1998.
3. Li, M.; Latoud, C.; Center, M. S.: Cloning and sequencing a cDNA
encoding human ribosomal protein S25. Gene 107: 329-333, 1991.
4. Miwa, T.; Sudo, K.; Nakamura, Y.; Imai, T.: Fifty sequenced-tagged
sites on human chromosome 11. Genomics 17: 211-214, 1993.
*FIELD* CN
Patti M. Sherman - updated: 4/6/1999
*FIELD* CD
Victor A. McKusick: 2/13/1992
*FIELD* ED
carol: 04/16/1999
carol: 4/6/1994
supermim: 3/16/1992
carol: 2/13/1992