Full text data of SH3BGRL3
SH3BGRL3
[Confidence: medium (present in either hRBCD or BSc_CH or PM22954596)]
SH3 domain-binding glutamic acid-rich-like protein 3 (SH3 domain-binding protein 1; SH3BP-1)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
SH3 domain-binding glutamic acid-rich-like protein 3 (SH3 domain-binding protein 1; SH3BP-1)
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q9H299
ID SH3L3_HUMAN Reviewed; 93 AA.
AC Q9H299; Q5T122;
DT 01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAR-2001, sequence version 1.
DT 22-JAN-2014, entry version 105.
DE RecName: Full=SH3 domain-binding glutamic acid-rich-like protein 3;
DE AltName: Full=SH3 domain-binding protein 1;
DE Short=SH3BP-1;
GN Name=SH3BGRL3; ORFNames=P1725;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, AND TISSUE
RP SPECIFICITY.
RC TISSUE=Pancreas;
RX PubMed=11444877; DOI=10.1006/bbrc.2001.5169;
RA Mazzocco M., Arrigo P., Egeo A., Maffei M., Vergano A., Di Lisi R.,
RA Ghiotto F., Ciccone E., Cinti R., Ravazzolo R., Scartezzini P.;
RT "A novel human homologue of the SH3BGR gene encodes a small protein
RT similar to glutaredoxin 1 of Escherichia coli.";
RL Biochem. Biophys. Res. Commun. 285:540-545(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Li N., Wan T., Zhang W., Cao X.;
RT "Novel human SH3 domain binding protein SH3BP-1.";
RL Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Hair follicle dermal papilla;
RA Seo J.M., Kim M.K., Kim Y.H., Lee H.M., Hwang S.Y., Farooq M.,
RA Im S.U., Chung J.E., Kim J.C.;
RT "A catalog of genes in the human dermal papilla cells as identified by
RT expressed sequence tags.";
RL Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A.,
RA Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K.,
RA Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D.,
RA Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G.,
RA Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M.,
RA Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J.,
RA Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M.,
RA Loveland J., Lovell J., Lush M.J., Lyne R., Martin S.,
RA Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S.,
RA Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C.,
RA Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z.,
RA Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E.,
RA Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A.,
RA Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R.,
RA Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V.,
RA Beck S., Rogers J., Bentley D.R.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Lung;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [6]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, MASS SPECTROMETRY, AND
RP CLEAVAGE OF INITIATOR METHIONINE.
RX PubMed=19413330; DOI=10.1021/ac9004309;
RA Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,
RA Mohammed S.;
RT "Lys-N and trypsin cover complementary parts of the phosphoproteome in
RT a refined SCX-based approach.";
RL Anal. Chem. 81:4493-4501(2009).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Leukemic T-cell;
RX PubMed=19690332; DOI=10.1126/scisignal.2000007;
RA Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,
RA Rodionov V., Han D.K.;
RT "Quantitative phosphoproteomic analysis of T cell receptor signaling
RT reveals system-wide modulation of protein-protein interactions.";
RL Sci. Signal. 2:RA46-RA46(2009).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [9]
RP STRUCTURE BY NMR, AND SUBCELLULAR LOCATION.
RX PubMed=15907482; DOI=10.1016/j.febslet.2005.04.011;
RA Xu C., Zheng P., Shen S., Xu Y., Wei L., Gao H., Wang S., Zhu C.,
RA Tang Y., Wu J., Zhang Q., Shi Y.;
RT "NMR structure and regulated expression in APL cell of human
RT SH3BGRL3.";
RL FEBS Lett. 579:2788-2794(2005).
CC -!- FUNCTION: Could act as a modulator of glutaredoxin biological
CC activity.
CC -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
CC -!- TISSUE SPECIFICITY: Ubiquitous.
CC -!- SIMILARITY: Belongs to the SH3BGR family.
CC -!- SIMILARITY: Contains 1 glutaredoxin domain.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AJ297915; CAC35770.1; -; mRNA.
DR EMBL; AF247790; AAL95695.1; -; mRNA.
DR EMBL; AF304163; AAG41412.1; -; mRNA.
DR EMBL; AL451139; CAI15827.1; -; Genomic_DNA.
DR EMBL; BC030135; AAH30135.1; -; mRNA.
DR PIR; JC7711; JC7711.
DR RefSeq; NP_112576.1; NM_031286.3.
DR UniGene; Hs.109051; -.
DR PDB; 1SJ6; NMR; -; A=1-93.
DR PDBsum; 1SJ6; -.
DR ProteinModelPortal; Q9H299; -.
DR SMR; Q9H299; 1-93.
DR IntAct; Q9H299; 1.
DR MINT; MINT-1547823; -.
DR PhosphoSite; Q9H299; -.
DR DMDM; 24638222; -.
DR PaxDb; Q9H299; -.
DR PRIDE; Q9H299; -.
DR DNASU; 83442; -.
DR Ensembl; ENST00000270792; ENSP00000270792; ENSG00000142669.
DR GeneID; 83442; -.
DR KEGG; hsa:83442; -.
DR UCSC; uc001blu.3; human.
DR CTD; 83442; -.
DR GeneCards; GC01P026605; -.
DR HGNC; HGNC:15568; SH3BGRL3.
DR HPA; HPA030848; -.
DR neXtProt; NX_Q9H299; -.
DR PharmGKB; PA37979; -.
DR eggNOG; NOG302258; -.
DR HOGENOM; HOG000095212; -.
DR HOVERGEN; HBG054781; -.
DR InParanoid; Q9H299; -.
DR OMA; IKLYYTT; -.
DR OrthoDB; EOG7GTT63; -.
DR PhylomeDB; Q9H299; -.
DR ChiTaRS; SH3BGRL3; human.
DR EvolutionaryTrace; Q9H299; -.
DR GeneWiki; SH3BGRL3; -.
DR GenomeRNAi; 83442; -.
DR NextBio; 72322; -.
DR PRO; PR:Q9H299; -.
DR ArrayExpress; Q9H299; -.
DR Bgee; Q9H299; -.
DR CleanEx; HS_SH3BGRL3; -.
DR Genevestigator; Q9H299; -.
DR GO; GO:0005737; C:cytoplasm; IDA:HPA.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR Gene3D; 3.40.30.10; -; 1.
DR InterPro; IPR006993; Glut_rich_SH3-bd.
DR InterPro; IPR002109; Glutaredoxin.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR PANTHER; PTHR12232; PTHR12232; 1.
DR Pfam; PF04908; SH3BGR; 1.
DR PIRSF; PIRSF008142; SH3-bind_E-rich_L; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Complete proteome; Cytoplasm; Nucleus;
KW Reference proteome.
FT INIT_MET 1 1 Removed.
FT CHAIN 2 93 SH3 domain-binding glutamic acid-rich-
FT like protein 3.
FT /FTId=PRO_0000220749.
FT DOMAIN 1 93 Glutaredoxin.
FT MOD_RES 2 2 N-acetylserine.
FT STRAND 5 8
FT STRAND 14 16
FT HELIX 17 30
FT STRAND 36 39
FT HELIX 44 53
FT STRAND 63 73
FT HELIX 74 81
FT TURN 82 84
FT HELIX 86 90
SQ SEQUENCE 93 AA; 10438 MW; C30BE3251D5B82CC CRC64;
MSGLRVYSTS VTGSREIKSQ QSEVTRILDG KRIQYQLVDI SQDNALRDEM RALAGNPKAT
PPQIVNGDQY CGDYELFVEA VEQNTLQEFL KLA
//
ID SH3L3_HUMAN Reviewed; 93 AA.
AC Q9H299; Q5T122;
DT 01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-MAR-2001, sequence version 1.
DT 22-JAN-2014, entry version 105.
DE RecName: Full=SH3 domain-binding glutamic acid-rich-like protein 3;
DE AltName: Full=SH3 domain-binding protein 1;
DE Short=SH3BP-1;
GN Name=SH3BGRL3; ORFNames=P1725;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, AND TISSUE
RP SPECIFICITY.
RC TISSUE=Pancreas;
RX PubMed=11444877; DOI=10.1006/bbrc.2001.5169;
RA Mazzocco M., Arrigo P., Egeo A., Maffei M., Vergano A., Di Lisi R.,
RA Ghiotto F., Ciccone E., Cinti R., Ravazzolo R., Scartezzini P.;
RT "A novel human homologue of the SH3BGR gene encodes a small protein
RT similar to glutaredoxin 1 of Escherichia coli.";
RL Biochem. Biophys. Res. Commun. 285:540-545(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Li N., Wan T., Zhang W., Cao X.;
RT "Novel human SH3 domain binding protein SH3BP-1.";
RL Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Hair follicle dermal papilla;
RA Seo J.M., Kim M.K., Kim Y.H., Lee H.M., Hwang S.Y., Farooq M.,
RA Im S.U., Chung J.E., Kim J.C.;
RT "A catalog of genes in the human dermal papilla cells as identified by
RT expressed sequence tags.";
RL Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A.,
RA Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K.,
RA Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D.,
RA Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G.,
RA Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M.,
RA Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J.,
RA Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M.,
RA Loveland J., Lovell J., Lush M.J., Lyne R., Martin S.,
RA Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S.,
RA Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C.,
RA Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z.,
RA Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E.,
RA Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A.,
RA Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R.,
RA Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V.,
RA Beck S., Rogers J., Bentley D.R.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Lung;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [6]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, MASS SPECTROMETRY, AND
RP CLEAVAGE OF INITIATOR METHIONINE.
RX PubMed=19413330; DOI=10.1021/ac9004309;
RA Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,
RA Mohammed S.;
RT "Lys-N and trypsin cover complementary parts of the phosphoproteome in
RT a refined SCX-based approach.";
RL Anal. Chem. 81:4493-4501(2009).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Leukemic T-cell;
RX PubMed=19690332; DOI=10.1126/scisignal.2000007;
RA Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,
RA Rodionov V., Han D.K.;
RT "Quantitative phosphoproteomic analysis of T cell receptor signaling
RT reveals system-wide modulation of protein-protein interactions.";
RL Sci. Signal. 2:RA46-RA46(2009).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [9]
RP STRUCTURE BY NMR, AND SUBCELLULAR LOCATION.
RX PubMed=15907482; DOI=10.1016/j.febslet.2005.04.011;
RA Xu C., Zheng P., Shen S., Xu Y., Wei L., Gao H., Wang S., Zhu C.,
RA Tang Y., Wu J., Zhang Q., Shi Y.;
RT "NMR structure and regulated expression in APL cell of human
RT SH3BGRL3.";
RL FEBS Lett. 579:2788-2794(2005).
CC -!- FUNCTION: Could act as a modulator of glutaredoxin biological
CC activity.
CC -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
CC -!- TISSUE SPECIFICITY: Ubiquitous.
CC -!- SIMILARITY: Belongs to the SH3BGR family.
CC -!- SIMILARITY: Contains 1 glutaredoxin domain.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AJ297915; CAC35770.1; -; mRNA.
DR EMBL; AF247790; AAL95695.1; -; mRNA.
DR EMBL; AF304163; AAG41412.1; -; mRNA.
DR EMBL; AL451139; CAI15827.1; -; Genomic_DNA.
DR EMBL; BC030135; AAH30135.1; -; mRNA.
DR PIR; JC7711; JC7711.
DR RefSeq; NP_112576.1; NM_031286.3.
DR UniGene; Hs.109051; -.
DR PDB; 1SJ6; NMR; -; A=1-93.
DR PDBsum; 1SJ6; -.
DR ProteinModelPortal; Q9H299; -.
DR SMR; Q9H299; 1-93.
DR IntAct; Q9H299; 1.
DR MINT; MINT-1547823; -.
DR PhosphoSite; Q9H299; -.
DR DMDM; 24638222; -.
DR PaxDb; Q9H299; -.
DR PRIDE; Q9H299; -.
DR DNASU; 83442; -.
DR Ensembl; ENST00000270792; ENSP00000270792; ENSG00000142669.
DR GeneID; 83442; -.
DR KEGG; hsa:83442; -.
DR UCSC; uc001blu.3; human.
DR CTD; 83442; -.
DR GeneCards; GC01P026605; -.
DR HGNC; HGNC:15568; SH3BGRL3.
DR HPA; HPA030848; -.
DR neXtProt; NX_Q9H299; -.
DR PharmGKB; PA37979; -.
DR eggNOG; NOG302258; -.
DR HOGENOM; HOG000095212; -.
DR HOVERGEN; HBG054781; -.
DR InParanoid; Q9H299; -.
DR OMA; IKLYYTT; -.
DR OrthoDB; EOG7GTT63; -.
DR PhylomeDB; Q9H299; -.
DR ChiTaRS; SH3BGRL3; human.
DR EvolutionaryTrace; Q9H299; -.
DR GeneWiki; SH3BGRL3; -.
DR GenomeRNAi; 83442; -.
DR NextBio; 72322; -.
DR PRO; PR:Q9H299; -.
DR ArrayExpress; Q9H299; -.
DR Bgee; Q9H299; -.
DR CleanEx; HS_SH3BGRL3; -.
DR Genevestigator; Q9H299; -.
DR GO; GO:0005737; C:cytoplasm; IDA:HPA.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR Gene3D; 3.40.30.10; -; 1.
DR InterPro; IPR006993; Glut_rich_SH3-bd.
DR InterPro; IPR002109; Glutaredoxin.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR PANTHER; PTHR12232; PTHR12232; 1.
DR Pfam; PF04908; SH3BGR; 1.
DR PIRSF; PIRSF008142; SH3-bind_E-rich_L; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Complete proteome; Cytoplasm; Nucleus;
KW Reference proteome.
FT INIT_MET 1 1 Removed.
FT CHAIN 2 93 SH3 domain-binding glutamic acid-rich-
FT like protein 3.
FT /FTId=PRO_0000220749.
FT DOMAIN 1 93 Glutaredoxin.
FT MOD_RES 2 2 N-acetylserine.
FT STRAND 5 8
FT STRAND 14 16
FT HELIX 17 30
FT STRAND 36 39
FT HELIX 44 53
FT STRAND 63 73
FT HELIX 74 81
FT TURN 82 84
FT HELIX 86 90
SQ SEQUENCE 93 AA; 10438 MW; C30BE3251D5B82CC CRC64;
MSGLRVYSTS VTGSREIKSQ QSEVTRILDG KRIQYQLVDI SQDNALRDEM RALAGNPKAT
PPQIVNGDQY CGDYELFVEA VEQNTLQEFL KLA
//