Full text data of TBC1D17
TBC1D17
[Confidence: low (only semi-automatic identification from reviews)]
TBC1 domain family member 17
Note: presumably soluble (membrane word is not in UniProt keywords or features)
TBC1 domain family member 17
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q9HA65
ID TBC17_HUMAN Reviewed; 648 AA.
AC Q9HA65; B4DT12; F5H1W7;
DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
read moreDT 18-MAY-2010, sequence version 2.
DT 22-JAN-2014, entry version 86.
DE RecName: Full=TBC1 domain family member 17;
GN Name=TBC1D17;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), AND
RP VARIANTS GLY-84 AND PRO-99.
RC TISSUE=Mammary gland;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), AND VARIANTS
RP GLY-84 AND PRO-99.
RC TISSUE=Skin;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Cervix carcinoma;
RX PubMed=20068231; DOI=10.1126/scisignal.2000475;
RA Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L.,
RA Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S.,
RA Mann M.;
RT "Quantitative phosphoproteomics reveals widespread full
RT phosphorylation site occupancy during mitosis.";
RL Sci. Signal. 3:RA3-RA3(2010).
CC -!- FUNCTION: May act as a GTPase-activating protein for Rab family
CC protein(s).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9HA65-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9HA65-2; Sequence=VSP_047344;
CC Note=No experimental confirmation available;
CC -!- SIMILARITY: Contains 1 Rab-GAP TBC domain.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AK022230; BAB13991.1; -; mRNA.
DR EMBL; AK300007; BAG61824.1; -; mRNA.
DR EMBL; AC118341; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC118342; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC003516; AAH03516.1; -; mRNA.
DR RefSeq; NP_001161694.1; NM_001168222.1.
DR RefSeq; NP_078958.2; NM_024682.2.
DR UniGene; Hs.631587; -.
DR ProteinModelPortal; Q9HA65; -.
DR SMR; Q9HA65; 313-546.
DR IntAct; Q9HA65; 13.
DR MINT; MINT-1409083; -.
DR STRING; 9606.ENSP00000221543; -.
DR PhosphoSite; Q9HA65; -.
DR DMDM; 296452920; -.
DR PaxDb; Q9HA65; -.
DR PRIDE; Q9HA65; -.
DR Ensembl; ENST00000221543; ENSP00000221543; ENSG00000104946.
DR Ensembl; ENST00000535102; ENSP00000446323; ENSG00000104946.
DR GeneID; 79735; -.
DR KEGG; hsa:79735; -.
DR UCSC; uc010ybg.2; human.
DR CTD; 79735; -.
DR GeneCards; GC19P050380; -.
DR HGNC; HGNC:25699; TBC1D17.
DR neXtProt; NX_Q9HA65; -.
DR PharmGKB; PA134922509; -.
DR eggNOG; COG5210; -.
DR HOGENOM; HOG000012710; -.
DR HOVERGEN; HBG057668; -.
DR InParanoid; Q9HA65; -.
DR OMA; QGSWAFS; -.
DR OrthoDB; EOG7HTHHR; -.
DR PhylomeDB; Q9HA65; -.
DR ChiTaRS; TBC1D17; human.
DR GenomeRNAi; 79735; -.
DR NextBio; 35508298; -.
DR PRO; PR:Q9HA65; -.
DR ArrayExpress; Q9HA65; -.
DR Bgee; Q9HA65; -.
DR CleanEx; HS_TBC1D17; -.
DR Genevestigator; Q9HA65; -.
DR GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR GO; GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC.
DR InterPro; IPR021935; DUF3548.
DR InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR Pfam; PF12068; DUF3548; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF47923; SSF47923; 2.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Complete proteome; GTPase activation;
KW Polymorphism; Reference proteome.
FT CHAIN 1 648 TBC1 domain family member 17.
FT /FTId=PRO_0000208045.
FT DOMAIN 310 520 Rab-GAP TBC.
FT COMPBIAS 596 631 Pro-rich.
FT VAR_SEQ 8 40 Missing (in isoform 2).
FT /FTId=VSP_047344.
FT VARIANT 84 84 D -> G (in dbSNP:rs8109661).
FT /FTId=VAR_060276.
FT VARIANT 99 99 L -> P (in dbSNP:rs3745486).
FT /FTId=VAR_024655.
SQ SEQUENCE 648 AA; 72728 MW; 1C09D2272FA95496 CRC64;
MEGAGYRVVF EKGGVYLHTS AKKYQDRDSL IAGVIRVVEK DNDVLLHWAP VEEAGDSTQI
LFSKKDSSGG DSCASEEEPT FDPDYEPDWA VISTVRPQLC HSEPTRGAEP SCPQGSWAFS
VSLGELKSIR RSKPGLSWAY LVLVTQAGGS LPALHFHRGG TRALLRVLSR YLLLASSPQD
SRLYLVFPHD SSALSNSFHH LQLFDQDSSN VVSRFLQDPY STTFSSFSRV TNFFRGALQP
QPEGAASDLP PPPDDEPEPG FEVISCVELG PRPTVERGPP VTEEEWARHV GPEGRLQQVP
ELKNRIFSGG LSPSLRREAW KFLLGYLSWE GTAEEHKAHI RKKTDEYFRM KLQWKSVSPE
QERRNSLLHG YRSLIERDVS RTDRTNKFYE GPENPGLGLL NDILLTYCMY HFDLGYVQGM
SDLLSPILYV IQNEVDAFWC FCGFMELVQG NFEESQETMK RQLGRLLLLL RVLDPLLCDF
LDSQDSGSLC FCFRWLLIWF KREFPFPDVL RLWEVLWTGL PGPNLHLLVA CAILDMERDT
LMLSGFGSNE ILKHINELTM KLSVEDVLTR AEALHRQLTA CPELPHNVQE ILGLAPPAEP
HSPSPTASPL PLSPTRAPPT PPPSTDTAPQ PDSSLEILPE EEDEGADS
//
ID TBC17_HUMAN Reviewed; 648 AA.
AC Q9HA65; B4DT12; F5H1W7;
DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
read moreDT 18-MAY-2010, sequence version 2.
DT 22-JAN-2014, entry version 86.
DE RecName: Full=TBC1 domain family member 17;
GN Name=TBC1D17;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), AND
RP VARIANTS GLY-84 AND PRO-99.
RC TISSUE=Mammary gland;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), AND VARIANTS
RP GLY-84 AND PRO-99.
RC TISSUE=Skin;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Cervix carcinoma;
RX PubMed=20068231; DOI=10.1126/scisignal.2000475;
RA Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L.,
RA Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S.,
RA Mann M.;
RT "Quantitative phosphoproteomics reveals widespread full
RT phosphorylation site occupancy during mitosis.";
RL Sci. Signal. 3:RA3-RA3(2010).
CC -!- FUNCTION: May act as a GTPase-activating protein for Rab family
CC protein(s).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9HA65-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9HA65-2; Sequence=VSP_047344;
CC Note=No experimental confirmation available;
CC -!- SIMILARITY: Contains 1 Rab-GAP TBC domain.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AK022230; BAB13991.1; -; mRNA.
DR EMBL; AK300007; BAG61824.1; -; mRNA.
DR EMBL; AC118341; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC118342; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC003516; AAH03516.1; -; mRNA.
DR RefSeq; NP_001161694.1; NM_001168222.1.
DR RefSeq; NP_078958.2; NM_024682.2.
DR UniGene; Hs.631587; -.
DR ProteinModelPortal; Q9HA65; -.
DR SMR; Q9HA65; 313-546.
DR IntAct; Q9HA65; 13.
DR MINT; MINT-1409083; -.
DR STRING; 9606.ENSP00000221543; -.
DR PhosphoSite; Q9HA65; -.
DR DMDM; 296452920; -.
DR PaxDb; Q9HA65; -.
DR PRIDE; Q9HA65; -.
DR Ensembl; ENST00000221543; ENSP00000221543; ENSG00000104946.
DR Ensembl; ENST00000535102; ENSP00000446323; ENSG00000104946.
DR GeneID; 79735; -.
DR KEGG; hsa:79735; -.
DR UCSC; uc010ybg.2; human.
DR CTD; 79735; -.
DR GeneCards; GC19P050380; -.
DR HGNC; HGNC:25699; TBC1D17.
DR neXtProt; NX_Q9HA65; -.
DR PharmGKB; PA134922509; -.
DR eggNOG; COG5210; -.
DR HOGENOM; HOG000012710; -.
DR HOVERGEN; HBG057668; -.
DR InParanoid; Q9HA65; -.
DR OMA; QGSWAFS; -.
DR OrthoDB; EOG7HTHHR; -.
DR PhylomeDB; Q9HA65; -.
DR ChiTaRS; TBC1D17; human.
DR GenomeRNAi; 79735; -.
DR NextBio; 35508298; -.
DR PRO; PR:Q9HA65; -.
DR ArrayExpress; Q9HA65; -.
DR Bgee; Q9HA65; -.
DR CleanEx; HS_TBC1D17; -.
DR Genevestigator; Q9HA65; -.
DR GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR GO; GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC.
DR InterPro; IPR021935; DUF3548.
DR InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR Pfam; PF12068; DUF3548; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF47923; SSF47923; 2.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Complete proteome; GTPase activation;
KW Polymorphism; Reference proteome.
FT CHAIN 1 648 TBC1 domain family member 17.
FT /FTId=PRO_0000208045.
FT DOMAIN 310 520 Rab-GAP TBC.
FT COMPBIAS 596 631 Pro-rich.
FT VAR_SEQ 8 40 Missing (in isoform 2).
FT /FTId=VSP_047344.
FT VARIANT 84 84 D -> G (in dbSNP:rs8109661).
FT /FTId=VAR_060276.
FT VARIANT 99 99 L -> P (in dbSNP:rs3745486).
FT /FTId=VAR_024655.
SQ SEQUENCE 648 AA; 72728 MW; 1C09D2272FA95496 CRC64;
MEGAGYRVVF EKGGVYLHTS AKKYQDRDSL IAGVIRVVEK DNDVLLHWAP VEEAGDSTQI
LFSKKDSSGG DSCASEEEPT FDPDYEPDWA VISTVRPQLC HSEPTRGAEP SCPQGSWAFS
VSLGELKSIR RSKPGLSWAY LVLVTQAGGS LPALHFHRGG TRALLRVLSR YLLLASSPQD
SRLYLVFPHD SSALSNSFHH LQLFDQDSSN VVSRFLQDPY STTFSSFSRV TNFFRGALQP
QPEGAASDLP PPPDDEPEPG FEVISCVELG PRPTVERGPP VTEEEWARHV GPEGRLQQVP
ELKNRIFSGG LSPSLRREAW KFLLGYLSWE GTAEEHKAHI RKKTDEYFRM KLQWKSVSPE
QERRNSLLHG YRSLIERDVS RTDRTNKFYE GPENPGLGLL NDILLTYCMY HFDLGYVQGM
SDLLSPILYV IQNEVDAFWC FCGFMELVQG NFEESQETMK RQLGRLLLLL RVLDPLLCDF
LDSQDSGSLC FCFRWLLIWF KREFPFPDVL RLWEVLWTGL PGPNLHLLVA CAILDMERDT
LMLSGFGSNE ILKHINELTM KLSVEDVLTR AEALHRQLTA CPELPHNVQE ILGLAPPAEP
HSPSPTASPL PLSPTRAPPT PPPSTDTAPQ PDSSLEILPE EEDEGADS
//