RBCC

Full text data of TMEM109

TMEM109 [Confidence: medium (present in either hRBCD or BSc_CH or PM22954596)]
Transmembrane protein 109 (Mitsugumin-23; Mg23; Flags: Precursor)

hRBCD IPI00031697
IPI00031697 Hypothetical protein Hypothetical protein membrane n/a n/a n/a n/a n/a n/a n/a n/a 1 n/a n/a n/a n/a n/a n/a n/a n/a 2 n/a n/a not mentioned n/a found at its expected molecular weight found at molecular weight

UniProt Q9BVC6
ID TM109_HUMAN Reviewed; 243 AA.
AC Q9BVC6;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
read moreDT 01-JUN-2001, sequence version 1.
DT 22-JAN-2014, entry version 83.
DE RecName: Full=Transmembrane protein 109;
DE AltName: Full=Mitsugumin-23;
DE Short=Mg23;
DE Flags: Precursor;
GN Name=TMEM109;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [2]
RP PROTEIN SEQUENCE OF 48-59 AND 207-215, AND MASS SPECTROMETRY.
RC TISSUE=Platelet;
RA Bienvenut W.V., Claeys D.;
RL Submitted (NOV-2005) to UniProtKB.
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus outer membrane; Multi-pass membrane
CC protein (By similarity). Endoplasmic reticulum membrane; Multi-
CC pass membrane protein (By similarity). Sarcoplasmic reticulum
CC membrane; Multi-pass membrane protein (By similarity).
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; BC001309; AAH01309.1; -; mRNA.
DR RefSeq; NP_076997.1; NM_024092.2.
DR UniGene; Hs.13662; -.
DR ProteinModelPortal; Q9BVC6; -.
DR IntAct; Q9BVC6; 6.
DR MINT; MINT-5003515; -.
DR STRING; 9606.ENSP00000227525; -.
DR PhosphoSite; Q9BVC6; -.
DR DMDM; 74733312; -.
DR PaxDb; Q9BVC6; -.
DR PeptideAtlas; Q9BVC6; -.
DR PRIDE; Q9BVC6; -.
DR Ensembl; ENST00000227525; ENSP00000227525; ENSG00000110108.
DR Ensembl; ENST00000536171; ENSP00000443990; ENSG00000110108.
DR GeneID; 79073; -.
DR KEGG; hsa:79073; -.
DR UCSC; uc001nqg.3; human.
DR CTD; 79073; -.
DR GeneCards; GC11P060681; -.
DR HGNC; HGNC:28771; TMEM109.
DR HPA; HPA011785; -.
DR neXtProt; NX_Q9BVC6; -.
DR PharmGKB; PA142670760; -.
DR eggNOG; NOG46846; -.
DR HOGENOM; HOG000126892; -.
DR HOVERGEN; HBG083664; -.
DR InParanoid; Q9BVC6; -.
DR OMA; PGQVQTF; -.
DR OrthoDB; EOG79CZ16; -.
DR PhylomeDB; Q9BVC6; -.
DR GenomeRNAi; 79073; -.
DR NextBio; 67865; -.
DR PRO; PR:Q9BVC6; -.
DR ArrayExpress; Q9BVC6; -.
DR Bgee; Q9BVC6; -.
DR CleanEx; HS_TMEM109; -.
DR Genevestigator; Q9BVC6; -.
DR GO; GO:0005737; C:cytoplasm; IDA:HPA.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR GO; GO:0031965; C:nuclear membrane; IDA:HPA.
DR GO; GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0071480; P:cellular response to gamma radiation; IMP:MGI.
DR GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR GO; GO:0060548; P:negative regulation of cell death; IMP:MGI.
PE 1: Evidence at protein level;
KW Complete proteome; Direct protein sequencing; Endoplasmic reticulum;
KW Membrane; Nucleus; Reference proteome; Sarcoplasmic reticulum; Signal;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1 33 Potential.
FT CHAIN 34 243 Transmembrane protein 109.
FT /FTId=PRO_0000044618.
FT TRANSMEM 84 104 Helical; (Potential).
FT TRANSMEM 136 156 Helical; (Potential).
FT TRANSMEM 159 179 Helical; (Potential).
FT TRANSMEM 186 205 Helical; (Potential).
SQ SEQUENCE 243 AA; 26210 MW; E405591236B94BB3 CRC64;
MAASSISSPW GKHVFKAILM VLVALILLHS ALAQSRRDFA PPGQQKREAP VDVLTQIGRS
VRGTLDAWIG PETMHLVSES SSQVLWAISS AISVAFFALS GIAAQLLNAL GLAGDYLAQG
LKLSPGQVQT FLLWGAGALV VYWLLSLLLG LVLALLGRIL WGLKLVIFLA GFVALMRSVP
DPSTRALLLL ALLILYALLS RLTGSRASGA QLEAKVRGLE RQVEELRWRQ RRAAKGARSV
EEE
//

RBCC Red Blood Cell Collection

Full text data of TMEM109