Full text data of ZNF547
ZNF547
[Confidence: low (only semi-automatic identification from reviews)]
Zinc finger protein 547
Note: presumably soluble (membrane word is not in UniProt keywords or features)
Zinc finger protein 547
Note: presumably soluble (membrane word is not in UniProt keywords or features)
UniProt
Q8IVP9
ID ZN547_HUMAN Reviewed; 402 AA.
AC Q8IVP9; A8K5Z9; Q96NC4;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
read moreDT 07-DEC-2004, sequence version 2.
DT 22-JAN-2014, entry version 96.
DE RecName: Full=Zinc finger protein 547;
GN Name=ZNF547;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Brain, and Neuroblastoma;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus (Potential).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8IVP9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8IVP9-2; Sequence=VSP_016347, VSP_016348;
CC Note=No experimental confirmation available;
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family.
CC -!- SIMILARITY: Contains 10 C2H2-type zinc fingers.
CC -!- SIMILARITY: Contains 1 KRAB domain.
CC -!- CAUTION: The gene of ZNF547 share a non-coding exon with TRAPPC2P.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AK055662; BAB70979.1; -; mRNA.
DR EMBL; AK291464; BAF84153.1; -; mRNA.
DR EMBL; CH471135; EAW72497.1; -; Genomic_DNA.
DR EMBL; BC042681; AAH42681.2; -; mRNA.
DR RefSeq; NP_775902.2; NM_173631.2.
DR UniGene; Hs.446620; -.
DR ProteinModelPortal; Q8IVP9; -.
DR SMR; Q8IVP9; 83-402.
DR PhosphoSite; Q8IVP9; -.
DR DMDM; 74762478; -.
DR PaxDb; Q8IVP9; -.
DR PRIDE; Q8IVP9; -.
DR DNASU; 284306; -.
DR Ensembl; ENST00000282282; ENSP00000282282; ENSG00000152433.
DR GeneID; 284306; -.
DR KEGG; hsa:284306; -.
DR UCSC; uc002qol.3; human.
DR CTD; 284306; -.
DR GeneCards; GC19P057875; -.
DR HGNC; HGNC:26432; ZNF547.
DR HPA; HPA056001; -.
DR neXtProt; NX_Q8IVP9; -.
DR PharmGKB; PA134931565; -.
DR eggNOG; COG5048; -.
DR HOGENOM; HOG000234617; -.
DR HOVERGEN; HBG018163; -.
DR InParanoid; Q8IVP9; -.
DR KO; K09228; -.
DR OMA; FMERSTL; -.
DR Reactome; REACT_71; Gene Expression.
DR GenomeRNAi; 284306; -.
DR NextBio; 94707; -.
DR PRO; PR:Q8IVP9; -.
DR ArrayExpress; Q8IVP9; -.
DR Bgee; Q8IVP9; -.
DR CleanEx; HS_ZNF547; -.
DR Genevestigator; Q8IVP9; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; -; 9.
DR InterPro; IPR001909; Krueppel-associated_box.
DR InterPro; IPR007087; Znf_C2H2.
DR InterPro; IPR015880; Znf_C2H2-like.
DR InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF109640; SSF109640; 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE 2: Evidence at transcript level;
KW Alternative splicing; Complete proteome; DNA-binding; Metal-binding;
KW Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1 402 Zinc finger protein 547.
FT /FTId=PRO_0000047644.
FT DOMAIN 11 82 KRAB.
FT ZN_FING 87 109 C2H2-type 1.
FT ZN_FING 156 178 C2H2-type 2.
FT ZN_FING 184 206 C2H2-type 3.
FT ZN_FING 212 234 C2H2-type 4.
FT ZN_FING 240 262 C2H2-type 5.
FT ZN_FING 268 290 C2H2-type 6.
FT ZN_FING 296 318 C2H2-type 7.
FT ZN_FING 324 346 C2H2-type 8.
FT ZN_FING 352 374 C2H2-type 9.
FT ZN_FING 378 400 C2H2-type 10.
FT VAR_SEQ 346 353 HTGERPYE -> YTEEESFQ (in isoform 2).
FT /FTId=VSP_016347.
FT VAR_SEQ 354 402 Missing (in isoform 2).
FT /FTId=VSP_016348.
SQ SEQUENCE 402 AA; 45956 MW; 5085F3EBA203C411 CRC64;
MAEMNPAQGH VVFEDVAIYF SQEEWGHLDE AQRLLYRDVM LENLALLSSL GCCHGAEDEE
APLEPGVSVG VSQVMAPKPC LSTQNTQPCE TCSSLLKDIL RLAEHDGTHP EQGLYTCPAH
LHQHQKEQIR EKLSRGDGGR PTFVKNHRVH MAGKTFLCSE CGKAFSHKHK LSDHQKIHTG
ERTYKCSKCG ILFMERSTLN RHQRTHTGER PYECNECGKA FLCKSHLVRH QTIHSGERPY
ECSECGKLFM WSSTLITHQR VHTGKRPYGC SECGKFFKCN SNLFRHYRIH TGKRSYGCSE
CGKFFMERST LSRHQRVHTG ERPYECNECG KFFSLKSVLI QHQRVHTGER PYECSECGKA
FLTKSHLICH QTVHTAAKQC SECGKFFRYN STLLRHQKVH TG
//
ID ZN547_HUMAN Reviewed; 402 AA.
AC Q8IVP9; A8K5Z9; Q96NC4;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
read moreDT 07-DEC-2004, sequence version 2.
DT 22-JAN-2014, entry version 96.
DE RecName: Full=Zinc finger protein 547;
GN Name=ZNF547;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Brain, and Neuroblastoma;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus (Potential).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8IVP9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8IVP9-2; Sequence=VSP_016347, VSP_016348;
CC Note=No experimental confirmation available;
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family.
CC -!- SIMILARITY: Contains 10 C2H2-type zinc fingers.
CC -!- SIMILARITY: Contains 1 KRAB domain.
CC -!- CAUTION: The gene of ZNF547 share a non-coding exon with TRAPPC2P.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AK055662; BAB70979.1; -; mRNA.
DR EMBL; AK291464; BAF84153.1; -; mRNA.
DR EMBL; CH471135; EAW72497.1; -; Genomic_DNA.
DR EMBL; BC042681; AAH42681.2; -; mRNA.
DR RefSeq; NP_775902.2; NM_173631.2.
DR UniGene; Hs.446620; -.
DR ProteinModelPortal; Q8IVP9; -.
DR SMR; Q8IVP9; 83-402.
DR PhosphoSite; Q8IVP9; -.
DR DMDM; 74762478; -.
DR PaxDb; Q8IVP9; -.
DR PRIDE; Q8IVP9; -.
DR DNASU; 284306; -.
DR Ensembl; ENST00000282282; ENSP00000282282; ENSG00000152433.
DR GeneID; 284306; -.
DR KEGG; hsa:284306; -.
DR UCSC; uc002qol.3; human.
DR CTD; 284306; -.
DR GeneCards; GC19P057875; -.
DR HGNC; HGNC:26432; ZNF547.
DR HPA; HPA056001; -.
DR neXtProt; NX_Q8IVP9; -.
DR PharmGKB; PA134931565; -.
DR eggNOG; COG5048; -.
DR HOGENOM; HOG000234617; -.
DR HOVERGEN; HBG018163; -.
DR InParanoid; Q8IVP9; -.
DR KO; K09228; -.
DR OMA; FMERSTL; -.
DR Reactome; REACT_71; Gene Expression.
DR GenomeRNAi; 284306; -.
DR NextBio; 94707; -.
DR PRO; PR:Q8IVP9; -.
DR ArrayExpress; Q8IVP9; -.
DR Bgee; Q8IVP9; -.
DR CleanEx; HS_ZNF547; -.
DR Genevestigator; Q8IVP9; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; -; 9.
DR InterPro; IPR001909; Krueppel-associated_box.
DR InterPro; IPR007087; Znf_C2H2.
DR InterPro; IPR015880; Znf_C2H2-like.
DR InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF109640; SSF109640; 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE 2: Evidence at transcript level;
KW Alternative splicing; Complete proteome; DNA-binding; Metal-binding;
KW Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1 402 Zinc finger protein 547.
FT /FTId=PRO_0000047644.
FT DOMAIN 11 82 KRAB.
FT ZN_FING 87 109 C2H2-type 1.
FT ZN_FING 156 178 C2H2-type 2.
FT ZN_FING 184 206 C2H2-type 3.
FT ZN_FING 212 234 C2H2-type 4.
FT ZN_FING 240 262 C2H2-type 5.
FT ZN_FING 268 290 C2H2-type 6.
FT ZN_FING 296 318 C2H2-type 7.
FT ZN_FING 324 346 C2H2-type 8.
FT ZN_FING 352 374 C2H2-type 9.
FT ZN_FING 378 400 C2H2-type 10.
FT VAR_SEQ 346 353 HTGERPYE -> YTEEESFQ (in isoform 2).
FT /FTId=VSP_016347.
FT VAR_SEQ 354 402 Missing (in isoform 2).
FT /FTId=VSP_016348.
SQ SEQUENCE 402 AA; 45956 MW; 5085F3EBA203C411 CRC64;
MAEMNPAQGH VVFEDVAIYF SQEEWGHLDE AQRLLYRDVM LENLALLSSL GCCHGAEDEE
APLEPGVSVG VSQVMAPKPC LSTQNTQPCE TCSSLLKDIL RLAEHDGTHP EQGLYTCPAH
LHQHQKEQIR EKLSRGDGGR PTFVKNHRVH MAGKTFLCSE CGKAFSHKHK LSDHQKIHTG
ERTYKCSKCG ILFMERSTLN RHQRTHTGER PYECNECGKA FLCKSHLVRH QTIHSGERPY
ECSECGKLFM WSSTLITHQR VHTGKRPYGC SECGKFFKCN SNLFRHYRIH TGKRSYGCSE
CGKFFMERST LSRHQRVHTG ERPYECNECG KFFSLKSVLI QHQRVHTGER PYECSECGKA
FLTKSHLICH QTVHTAAKQC SECGKFFRYN STLLRHQKVH TG
//