2A5B_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: PPP2R5B
Protein names and data: 2A5B_HUMAN , Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform , PP2A B subunit isoform B'-beta; PP2A B subunit isoform B56-beta; PP2A B subunit isoform PR61-beta; PP2A B subunit isoform R5-beta Lenght: 497 a.a.
Mass: 57393 Da
fasta formatted sequence
Function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.
Cellular location: Cytoplasm.
Tissue specificity: Highest expression in brain.

Database cross-references

UniProt: Q15173
Ensembl: ENST00000164133
MIM: 601644
neXtProt: NX_Q15173
Antibodypedia: Q15173 (may not find the protein thus also not any antibody)
Local full text data: click here

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