A1AG1_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ORM1 , AGP1
Protein names and data: A1AG1_HUMAN , Alpha-1-acid glycoprotein 1; AGP 1 , Orosomucoid-1; OMD 1; Flags: Precursor Lenght: 201 a.a.
Mass: 23512 Da
fasta formatted sequence
Function: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.
Cellular location: Secreted.
Tissue specificity: Expressed by the liver and secreted in plasma.

Genetic variants

Three common alleles of ORM1 are known. ORM1*F1 has Gln-38/Val-174; ORM1*F2 has Gln-38/Met-174 and ORM1*S has Arg- 38/Val-174. The sequence shown is that of allele ORM1*F1.

Database cross-references

UniProt: P02763
Ensembl: ENST00000259396
MIM: 138600
neXtProt: NX_P02763
Antibodypedia: P02763 (may not find the protein thus also not any antibody)
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