ACBP_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: DBI
Protein names and data: ACBP_HUMAN , Acyl-CoA-binding protein; ACBP , Diazepam-binding inhibitor; DBI; Endozepine; EP Lenght: 87 a.a.
Mass: 10044 Da
fasta formatted sequence
Function: Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
Cellular location: Endoplasmic reticulum. Golgi apparatus. Note=Golgi localization is dependent on ligand binding.
Tissue specificity: Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart.

Genetic variants

Database cross-references

UniProt: P07108
Ensembl: ENST00000311521
Ensembl: ENST00000355857
Ensembl: ENST00000393103
Ensembl: ENST00000409094
Ensembl: ENST00000535617
Ensembl: ENST00000535757
Ensembl: ENST00000542275
MIM: 125950
neXtProt: NX_P07108
Antibodypedia: P07108 (may not find the protein thus also not any antibody)
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