ACLY_HUMAN

Source: hRBCD ; ID: IPI00021290
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: ACLY
Protein names and data: ACLY_HUMAN , ATP-citrate synthase; 2.3.3.8 , ATP-citrate (pro-S-)-lyase; ACL; Citrate cleavage enzyme Lenght: 1101 a.a.
Mass: 120839 Da
fasta formatted sequence
Function: ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.
Catalytic activity: ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA.
Cellular location: Cytoplasm.

Genetic variants

Database cross-references

UniProt: P53396
Ensembl: ENST00000352035
Ensembl: ENST00000353196
Ensembl: ENST00000393896
Ensembl: ENST00000564506
Ensembl: ENST00000567793
Ensembl: ENST00000590151
MIM: 108728
neXtProt: NX_P53396
Antibodypedia: P53396 (may not find the protein thus also not any antibody)
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