ADK_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: ADK
Protein names and data: ADK_HUMAN , Adenosine kinase; AK; 2.7.1.20 , Adenosine 5'-phosphotransferase Lenght: 362 a.a.
Mass: 40545 Da
fasta formatted sequence

Function: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
Catalytic activity: ATP + adenosine = ADP + AMP.
Pathway: Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine: step 1/1.
Disease:
Cellular location: Isoform 1: Nucleus. Isoform 2: Cytoplasm.
Tissue specificity: Widely expressed. Highest level in placenta, liver, muscle and kidney.

Genetic variants

Database cross-references

UniProt: P55263
Ensembl: ENST00000286621
Ensembl: ENST00000372734
Ensembl: ENST00000539909
Ensembl: ENST00000541550
MIM: 102750
MIM: 614300
neXtProt: NX_P55263
Antibodypedia: P55263 (may not find the protein thus also not any antibody)
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