AGFG1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: AGFG1 , HRB, RAB, RIP
Protein names and data: AGFG1_HUMAN , Arf-GAP domain and FG repeat-containing protein 1 , HIV-1 Rev-binding protein; Nucleoporin-like protein RIP; Rev-interacting protein; Rev/Rex activation domain-binding protein Lenght: 562 a.a.
Mass: 58260 Da
fasta formatted sequence
Function: Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element- containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
Cellular location: Nucleus. Cytoplasmic vesicle.
Tissue specificity: Ubiquitously expressed.

Database cross-references

UniProt: P52594
Ensembl: ENST00000310078
Ensembl: ENST00000373671
Ensembl: ENST00000409171
MIM: 600862
neXtProt: NX_P52594
Antibodypedia: P52594 (may not find the protein thus also not any antibody)
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