AIDA_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: AIDA , C1orf80
Protein names and data: AIDA_HUMAN , Axin interactor, dorsalization-associated protein , Axin interaction partner and dorsalization antagonist Lenght: 306 a.a.
Mass: 35023 Da
fasta formatted sequence
Function: Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
Tissue specificity: Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle.

Database cross-references

UniProt: Q96BJ3
Ensembl: ENST00000340020
Ensembl: ENST00000355727
MIM: 612375
neXtProt: NX_Q96BJ3
Antibodypedia: Q96BJ3 (may not find the protein thus also not any antibody)
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