AKCL2_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: AKR1E2 , AKR1CL2, AKRDC1
Protein names and data: AKCL2_HUMAN , 1,5-anhydro-D-fructose reductase; AF reductase; 1.1.1.263 , Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; LoopADR; Testis-specific protein; hTSP Lenght: 320 a.a.
Mass: 36589 Da
fasta formatted sequence
Function: Catalyzes the NADPH-dependent reduction of 1,5-anhydro- D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones (By similarity). Has low NADPH-dependent reductase activity towards 9,10- phenanthrenequinone (in vitro).
Catalytic activity: 1,5-anhydro-D-glucitol + NADP(+) = 1,5- anhydro-D-fructose + NADPH.
Cellular location: Cytoplasm (Potential).
Tissue specificity: Testis-specific.

Genetic variants

Database cross-references

UniProt: Q96JD6
Ensembl: ENST00000298375
Ensembl: ENST00000334019
Ensembl: ENST00000345253
Ensembl: ENST00000463345
Ensembl: ENST00000532248
neXtProt: NX_Q96JD6
Antibodypedia: Q96JD6 (may not find the protein thus also not any antibody)
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