AL3A1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ALDH3A1 , ALDH3
Protein names and data: AL3A1_HUMAN , Aldehyde dehydrogenase, dimeric NADP-preferring; 1.2.1.5 , ALDHIII; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase family 3 member A1 Lenght: 453 a.a.
Mass: 50395 Da
fasta formatted sequence
Function: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
Catalytic activity: An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H.
Cellular location: Cytoplasm.
Tissue specificity: High levels in stomach, esophagus and lung; low level in the liver and kidney.

Genetic variants

Database cross-references

UniProt: P30838
Ensembl: ENST00000225740
Ensembl: ENST00000444455
Ensembl: ENST00000457500
MIM: 100660
neXtProt: NX_P30838
Antibodypedia: P30838 (may not find the protein thus also not any antibody)
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