RBCC Red Blood Cell Collection

ALDR_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: AKR1B1 , ALDR1
Protein names and data: ALDR_HUMAN , Aldose reductase; AR; 1.1.1.21 , Aldehyde reductase; Aldo-keto reductase family 1 member B1 Lenght: 316 a.a.
Mass: 35853 Da
fasta formatted sequence
Function: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Catalytic activity: Alditol + NAD(P)(+) = aldose + NAD(P)H.
Cellular location: Cytoplasm.
Tissue specificity: Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress.

Genetic variants

15 - 15 I -> F (in dbSNP:rs5054). VAR_014743 5054
42 - 42 H -> L (in dbSNP:rs5056). VAR_014744 5056
73 - 73 L -> V (in dbSNP:rs5057). VAR_014745 5057
90 - 90 K -> E (in dbSNP:rs2229542). VAR_048213 2229542
204 - 204 G -> S (in dbSNP:rs5061). VAR_014746 5061
288 - 288 T -> I (in dbSNP:rs5062). VAR_014747 5062

Database cross-references

UniProt: P15121
Ensembl: ENST00000285930
MIM: 103880
neXtProt: NX_P15121
Antibodypedia: P15121 (may not find the protein thus also not any antibody)
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