AMPB_HUMAN
Source: PM19886704PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: RNPEP , APB
Protein names and data: AMPB_HUMAN , Aminopeptidase B; AP-B; 3.4.11.6 , Arginine aminopeptidase; Arginyl aminopeptidase Lenght: 650 a.a.
Mass: 72596 Da
fasta formatted sequence
Function: Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(- 1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4) (By similarity).
Catalytic activity: Release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys.
Cellular location: Secreted (By similarity).
Genetic variants
Database cross-references
UniProt: Q9H4A4Ensembl: ENST00000295640
MIM: 602675
neXtProt: NX_Q9H4A4
Antibodypedia: Q9H4A4 (may not find the protein thus also not any antibody)
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