AMPL_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: LAP3 , LAPEP, PEPS
Protein names and data: AMPL_HUMAN , Cytosol aminopeptidase; 3.4.11.1 , Leucine aminopeptidase 3; LAP-3; Leucyl aminopeptidase; Peptidase S; Proline aminopeptidase; 3.4.11.5; Prolyl aminopeptidase Lenght: 519 a.a.
Mass: 56166 Da
fasta formatted sequence

Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
Catalytic activity: Release of an N-terminal amino acid, Xaa-|- Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low. Release of N-terminal proline from a peptide.
Cellular location: Cytoplasm.

Database cross-references

UniProt: P28838
Ensembl: ENST00000226299
Ensembl: ENST00000606142
MIM: 170250
neXtProt: NX_P28838
Antibodypedia: P28838 (may not find the protein thus also not any antibody)
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