AN13A_HUMAN

Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ANKRD13A , ANKRD13
Protein names and data: AN13A_HUMAN , Ankyrin repeat domain-containing protein 13A , Protein KE03 Lenght: 590 a.a.
Mass: 67619 Da
fasta formatted sequence
Function: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand- activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
Cellular location: Cell membrane. Late endosome. Note=Interaction with EGFR may enhance association with the cell membrane.

Genetic variants

Database cross-references

UniProt: Q8IZ07
Ensembl: ENST00000261739
MIM: 615123
neXtProt: NX_Q8IZ07
Antibodypedia: Q8IZ07 (may not find the protein thus also not any antibody)
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