AN32B_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ANP32B , APRIL, PHAPI2
Protein names and data: AN32B_HUMAN , Acidic leucine-rich nuclear phosphoprotein 32 family member B , Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; PHAPI2; Silver-stainable protein SSP29 Lenght: 251 a.a.
Mass: 28788 Da
fasta formatted sequence
Function: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
Cellular location: Isoform 1: Nucleus. Note=Accumulates in the nuclei at the S phase (By similarity). Isoform 2: Cytoplasm. Note=Lacks a nuclear localization signal.
Tissue specificity: Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.

Database cross-references

UniProt: Q92688
Ensembl: ENST00000339399
neXtProt: NX_Q92688
Antibodypedia: Q92688 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.