ANK3_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ANK3
Protein names and data: ANK3_HUMAN , Ankyrin-3; ANK-3 , Ankyrin-G Lenght: 4377 a.a.
Mass: 480410 Da
fasta formatted sequence
Function: In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments.
Disease:
Cellular location: Cytoplasm, cytoskeleton. Cell junction, synapse, postsynaptic cell membrane (By similarity). Lysosome (By similarity). Note=In skeletal muscle, localized at costameres and neuromuscular junctions (By similarity). In macrophages, associated with lysosomes (By similarity).
Tissue specificity: Expressed in brain, neurons and other tissues.

Genetic variants

Database cross-references

UniProt: Q12955
Ensembl: ENST00000280772
Ensembl: ENST00000355288
Ensembl: ENST00000373827
Ensembl: ENST00000503366
MIM: 600465
neXtProt: NX_Q12955
Antibodypedia: Q12955 (may not find the protein thus also not any antibody)
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