ANT3_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: SERPINC1 , AT3 , PRO0309
Protein names and data: ANT3_HUMAN , Antithrombin-III; ATIII , Serpin C1; Flags: Precursor Lenght: 464 a.a.
Mass: 52602 Da
fasta formatted sequence

Function: Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
Disease:
Cellular location: Secreted, extracellular space.
Tissue specificity: Found in plasma.

Genetic variants

Database cross-references

UniProt: P01008
Ensembl: ENST00000367698
MIM: 107300
MIM: 613118
neXtProt: NX_P01008
Antibodypedia: P01008 (may not find the protein thus also not any antibody)
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