Source: PM19886704
Marked as 'Membrane associated protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: ANXA2 , ANX2, ANX2L4, CAL1H, LPC2D
Protein names and data: ANXA2_HUMAN , Annexin A2 , Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36 Lenght: 339 a.a.
Mass: 38604 Da
fasta formatted sequence

Function: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
Cellular location: Secreted, extracellular space, extracellular matrix, basement membrane. Melanosome. Note=In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.

Genetic variants

Database cross-references

UniProt: P07355
Ensembl: ENST00000332680
Ensembl: ENST00000396024
Ensembl: ENST00000421017
Ensembl: ENST00000451270
MIM: 151740
neXtProt: NX_P07355
Antibodypedia: P07355 (may not find the protein thus also not any antibody)
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