AP1S1_HUMAN

Source: PM19886704
PM23856902
PM22954596
Marked as 'Membrane associated protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: AP1S1 , AP19, CLAPS1
Protein names and data: AP1S1_HUMAN , AP-1 complex subunit sigma-1A , Adapter-related protein complex 1 subunit sigma-1A; Adaptor protein complex AP-1 subunit sigma-1A; Clathrin assembly protein complex 1 sigma-1A small chain; Clathrin coat assembly protein AP19; Golgi adaptor HA1/AP1 adaptin sigma-1A subunit; HA1 19 kDa subunit; Sigma 1a subunit of AP-1 clathrin; Sigma-adaptin 1A; Sigma1A-adaptin Lenght: 158 a.a.
Mass: 18733 Da
fasta formatted sequence

Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Disease:
Cellular location: Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Tissue specificity: Widely expressed.

Database cross-references

UniProt: P61966
Ensembl: ENST00000337619
Ensembl: ENST00000443943
MIM: 603531
MIM: 609313
neXtProt: NX_P61966
Antibodypedia: P61966 (may not find the protein thus also not any antibody)
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