AP3S1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: AP3S1 , CLAPS3
Protein names and data: AP3S1_HUMAN , AP-3 complex subunit sigma-1 , AP-3 complex subunit sigma-3A; Adapter-related protein complex 3 subunit sigma-1; Clathrin-associated/assembly/adapter protein, small 3; Sigma-3A-adaptin; Sigma3A-adaptin; Sigma-adaptin 3a Lenght: 193 a.a.
Mass: 21732 Da
fasta formatted sequence
Function: Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Cellular location: Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Tissue specificity: Present in all adult tissues examined.

Genetic variants

Database cross-references

UniProt: Q92572
Ensembl: ENST00000316788
MIM: 601507
neXtProt: NX_Q92572
Antibodypedia: Q92572 (may not find the protein thus also not any antibody)
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