APC5_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ANAPC5 , APC5
Protein names and data: APC5_HUMAN , Anaphase-promoting complex subunit 5; APC5 , Cyclosome subunit 5 Lenght: 755 a.a.
Mass: 85077 Da
fasta formatted sequence
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Pathway: Protein modification; protein ubiquitination.

Genetic variants

Database cross-references

UniProt: Q9UJX4
Ensembl: ENST00000261819
Ensembl: ENST00000344395
Ensembl: ENST00000441917
Ensembl: ENST00000536366
Ensembl: ENST00000605884
Ensembl: ENST00000605978
Ensembl: ENST00000607064
Ensembl: ENST00000607392
MIM: 606948
neXtProt: NX_Q9UJX4
Antibodypedia: Q9UJX4 (may not find the protein thus also not any antibody)
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