ARI2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ARIH2 , ARI2, TRIAD1 , HT005
Protein names and data: ARI2_HUMAN , E3 ubiquitin-protein ligase ARIH2; ARI-2; Protein ariadne-2 homolog; 6.3.2.- , Triad1 protein Lenght: 493 a.a.
Mass: 57819 Da
fasta formatted sequence
Function: E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys- 63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.
Pathway: Protein modification; protein ubiquitination.
Cellular location: Nucleus. Cytoplasm.
Tissue specificity: Widely expressed with higher expression in granulocytes.

Genetic variants

Database cross-references

UniProt: O95376
Ensembl: ENST00000356401
Ensembl: ENST00000449376
MIM: 605615
neXtProt: NX_O95376
Antibodypedia: O95376 (may not find the protein thus also not any antibody)
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