AT12A_HUMAN

Source: PM19886704
PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ATP12A , ATP1AL1
Protein names and data: AT12A_HUMAN , Potassium-transporting ATPase alpha chain 2; 3.6.3.10 , Non-gastric H(+)/K(+) ATPase subunit alpha; Proton pump Lenght: 1039 a.a.
Mass: 115511 Da
fasta formatted sequence
Function: Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues.
Catalytic activity: ATP + H(2)O + H(+)(In) + K(+)(Out) = ADP + phosphate + H(+)(Out) + K(+)(In).
Cellular location: Membrane; Multi-pass membrane protein.
Tissue specificity: Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level).

Genetic variants

Database cross-references

UniProt: P54707
Ensembl: ENST00000218548
Ensembl: ENST00000381946
MIM: 182360
neXtProt: NX_P54707
Antibodypedia: P54707 (may not find the protein thus also not any antibody)
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