AT1A1_HUMAN

Source: hRBCD ; ID: IPI00006482
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: ATP1A1
Protein names and data: AT1A1_HUMAN , Sodium/potassium-transporting ATPase subunit alpha-1; Na(+)/K(+) ATPase alpha-1 subunit; 3.6.3.9 , Sodium pump subunit alpha-1; Flags: Precursor Lenght: 1023 a.a.
Mass: 112896 Da
fasta formatted sequence
Function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Catalytic activity: ATP + H(2)O + Na(+)(In) + K(+)(Out) = ADP + phosphate + Na(+)(Out) + K(+)(In).
Cellular location: Cell membrane; Multi-pass membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Genetic variants

Database cross-references

UniProt: P05023
Ensembl: ENST00000295598
Ensembl: ENST00000369496
Ensembl: ENST00000537345
MIM: 182310
neXtProt: NX_P05023
Antibodypedia: P05023 (may not find the protein thus also not any antibody)
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